Produkte von DIMA Biotech
DIMA Biotechnology ist auf präklinische Forschungs- und Entwicklungslösungen für die Biopharmaindustrie spezialisiert. Das umfangreiche Portfolio umfasst mehr als 1.200 Antikörper sowie über 1.500 Proteine und Zytokine. Zu den Proteinen zählt auch eine große Auswahl an vollständigen Transmembranproteinen, für die DIMA mehrere Plattformen entwickelt hat, darunter Nanodisc, virusähnliche Partikel, Membran-Nanopartikel und Exosome. Alle Plattformen basieren auf Säugetier-Expressionssystemen und stellen Membranproteine in voller Länge als lösliche Proteinprodukte mit nativer Konformation und Aktivität her.
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Anti-TEM1(ontuxizumab biosimilar) mAb
Artikelnummer: DIM-BME100216.100
Protein function: May play a role in tumor angiogenesis. [The UniProt Consortium]
| Schlagworte: | Anti-CD248, Anti-CD164L1, Anti-TEM1(ontuxizumab biosimilar) mAb |
| Wirt: | Chimeric Humanized |
| Spezies-Reaktivität: | human |
ab 120,00 €
Anti-CD73(oleclumab biosimilar) mAb
Artikelnummer: DIM-BME100217.100
Protein function: Hydrolyzes extracellular nucleotides into membrane permeable nucleosides. Exhibits AMP-, NAD-, and NMN-nucleosidase activities. [The UniProt Consortium]
| Schlagworte: | Anti-NT5E, Anti-5'-Nucleotidase, Anti-5'-NT, Anti-NT5, Anti-NTE, Anti-CD73(oleclumab biosimilar) mAb |
| Wirt: | Human |
| Spezies-Reaktivität: | human |
ab 120,00 €
Anti-CD73(BMS 986179) mAb
Artikelnummer: DIM-BME100218.100
Protein function: Hydrolyzes extracellular nucleotides into membrane permeable nucleosides. Exhibits AMP-, NAD-, and NMN-nucleosidase activities. [The UniProt Consortium]
| Schlagworte: | Anti-NT5E, Anti-5'-Nucleotidase, Anti-5'-NT, Anti-NT5, Anti-NTE, Anti-CD73(BMS 986179) mAb |
| Wirt: | Human |
| Spezies-Reaktivität: | human |
ab 120,00 €
Anti-CD39(perenostobart biosimilar) mAb
Artikelnummer: DIM-BME100219.100
Protein function: In the nervous system, could hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission. Could also be implicated in the prevention of platelet aggregation by hydrolyzing platelet-activating ADP to AMP. Hydrolyzes ATP and ADP equally well. [The UniProt Consortium]
| Schlagworte: | Anti-ENTPD1, Anti-CD39(perenostobart biosimilar) mAb |
| Wirt: | Human |
| Spezies-Reaktivität: | human |
ab 120,00 €
Anti-FGFR3(vofatamab biosimilar) mAb
Artikelnummer: DIM-BME100220.100
Protein function: Tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of cell proliferation, differentiation and apoptosis. Plays an essential role in the regulation of chondrocyte differentiation, proliferation and apoptosis, and is...
| Schlagworte: | Anti-FGFR-3, Anti-CD333, Anti-JTK4, Anti-FGFR3(vofatamab biosimilar) mAb |
| Wirt: | Humanized |
| Spezies-Reaktivität: | human |
ab 120,00 €
Anti-IL5RA(benralizumab biosimilar) mAb
Artikelnummer: DIM-BME100221.100
Protein function: This is the receptor for interleukin-5. The alpha chain binds to IL5. [The UniProt Consortium]
| Schlagworte: | Anti-CDw125, Anti-CD125, Anti-IL5R, Anti-IL5RA(benralizumab biosimilar) mAb |
| Wirt: | Humanized |
| Spezies-Reaktivität: | human |
ab 120,00 €
Anti-TNFSF15(PF-06480605 biosimilar) mAb
Artikelnummer: DIM-BME100222.100
Protein function: Receptor for TNFRSF25 and TNFRSF6B. Mediates activation of NF-kappa-B. Inhibits vascular endothelial growth and angiogenesis (in vitro). Promotes activation of caspases and apoptosis. [The UniProt Consortium]
| Schlagworte: | Anti-TL1, Anti-VEGI, Anti-TNFSF15(PF-06480605 biosimilar) mAb |
| Wirt: | Humanized |
| Spezies-Reaktivität: | human |
ab 120,00 €
Anti-IL12B(ebdarokimab biosimilar) mAb
Artikelnummer: DIM-BME100223.100
Protein function: Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. [The UniProt Consortium]
| Schlagworte: | Anti-IL-12B, Anti-CLMF p40, Anti-IL-12 subunit p40, Anti-NKSF2, Anti-IL12B(ebdarokimab biosimilar) mAb |
| Wirt: | Humanized |
| Spezies-Reaktivität: | human |
ab 120,00 €
Anti-LY6E(RG7841 biosimilar) mAb
Artikelnummer: DIM-BME100224.100
Protein function: GPI-anchored cell surface protein that regulates T- lymphocytes proliferation, differentiation, and activation. Regulates the T-cell receptor (TCR) signaling by interacting with component CD3Z/CD247 at the plasma membrane, leading to CD3Z/CD247 phosphorylation modulation. Restricts the entry of...
| Schlagworte: | Anti-RIGE, Anti-SCA2, Anti-RIG-E, Anti-SCA-2, Anti-TSA-1, Anti-LY6E(RG7841 biosimilar) mAb |
| Wirt: | Humanized |
| Spezies-Reaktivität: | human |
ab 120,00 €
Anti-CD79B (polatuzumab biosimilar) antibody, Rabbit IgG...
Artikelnummer: DIM-BME100225.100
Protein function: Required in cooperation with CD79A for initiation of the signal transduction cascade activated by the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Enhances phosphorylation of CD79A, possibly by...
| Schlagworte: | Anti-AGM6, Anti-B29, Anti-IGB, Anti-CD79B (polatuzumab biosimilar) antibody, Rabbit IgG Chimeric mAb |
| Wirt: | Chimeric Rabbit |
| Spezies-Reaktivität: | human |
ab 120,00 €
Anti-CRTAM(Oxford Biotherapeutics 5A11) mAb
Artikelnummer: DIM-BME100226.100
Protein function: Mediates heterophilic cell-cell adhesion which regulates the activation, differentiation and tissue retention of various T-cell subsets. Interaction with CADM1 promotes natural killer (NK) cell cytotoxicity and IFNG/interferon-gamma secretion by CD8+ T- cells in vitro as well as NK cell-mediated...
| Schlagworte: | Anti-CD355, Anti-CRTAM(Oxford Biotherapeutics 5A11) mAb |
| Wirt: | Humanized |
| Spezies-Reaktivität: | human |
ab 120,00 €
Anti-CRTAM(HuC110-34 biosimilar) mAb
Artikelnummer: DIM-BME100227.100
Protein function: Mediates heterophilic cell-cell adhesion which regulates the activation, differentiation and tissue retention of various T-cell subsets. Interaction with CADM1 promotes natural killer (NK) cell cytotoxicity and IFNG/interferon-gamma secretion by CD8+ T- cells in vitro as well as NK cell-mediated...
| Schlagworte: | Anti-CD355, Anti-CRTAM(HuC110-34 biosimilar) mAb |
| Wirt: | Humanized |
| Spezies-Reaktivität: | human |
ab 120,00 €