Produkte von Chimerigen Laboratories
Chimerigen entwickelt und produziert einzigartige, Immunglobulin-basierte, chimäre Fusionsproteine und verwandte Forschungsprodukte mit Hilfe modernster zell- und molekularbiologischen Techniken. Diese Reagenzien werden erfolgreich in der biomedizinischen Grundlagen- und in angewandter Forschung eingesetzt.
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IL-4 (human):Fc (human) (rec.) MultiPack
Artikelnummer: CHI-HF-21004-C010
Interleukin-4 (IL-4) is a cytokine produced by type 2 helper T cells, the Th2 cells. These cells tends to make a specific set of lymphokines including IL-4, IL-5, IL-6, IL-10, IL-13, IL-3 and GM-CSF and fail to produce IL-2, IFN-gamma, and lymphotoxin (TNF-beta). In addition, mast cells can produce IL-4. IL-4 exerts...
| Schlagworte: | IL4, IL-4, BSF-1, Binetrakin, Pitrakinra, Interleukin-4, B-cell stimulatory factor 1, Lymphocyte stimulatory factor 1,... |
| Anwendung: | Bioassays |
| Exprimiert in: | Hamster cells |
| Ursprungsart: | human |
ab 209,00 €
IL-10 (human):Fc (human) (rec.) (non-lytic)
Artikelnummer: CHI-HF-22010-C010
The extracellular domain of human IL-10 (aa 19-178) is fused at the C-terminus to the Fc portion of a mutant human IgG1. Lyophilized from 0.2µm-filtered solution in PBS. Shows the biological function of the IL-10 moiety and exerts a prolonged circulating half-life caused by the modified Fc domain. Interleukin-10...
| Schlagworte: | IL10, CSIF, IL-10, Interleukin-10, Cytokine synthesis inhibitory factor |
| Anwendung: | Bioassays |
| Exprimiert in: | Hamster cells |
| Ursprungsart: | human |
ab 264,00 €
IL-1alpha (human) (rec.) (His)
Artikelnummer: CHI-HR-20001A-C010
The most prominent members of the interleukin-1 (IL-1) superfamily are IL-1alpha and IL-1beta. They lack a signal peptide and are secreted by an unconventional, endoplasmic reticulum-Golgi-independent mechanism. IL-1alpha was reported to be more widely and constitutively expressed and has intracellular functions,...
| Schlagworte: | IL1A, IL1F1, IL-1 alpha, Hematopoietin-1, Interleukin-1 alpha, Interleukin-1alpha, IL-1F1, IL-1A |
| Anwendung: | Bioassays |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
ab 209,00 €
Interleukin-8, human recombinant (rHuIL-8) (His)
Artikelnummer: CHI-HR-20008-C010
Interleukin-8 (IL-8) was originally discovered as a neutrophil chemotactic and activating factor and is a member of the alpha (CXC) subfamily of chemokines (including also platelet factor 4, GRO, IP-10, etc.). Many cell types, including monocyte/macrophages, T cells, neutrophils, fibroblasts, endothelial cells,...
| Schlagworte: | Interleukin-8, CXCL8, C-X-C Motif Chemokine 8, Emoctakin, GCP-1, LAI, MDNCF, MONAP, NAP-1, NCF, TCF |
| Anwendung: | Bioassays |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
ab 187,00 €
IL-15 (human) (rec.) (His)
Artikelnummer: CHI-HR-20015-C010
Interleukin-15 (IL-15) has a broad spectrum of biological activities. It is crucial for the development, proliferation, survival and differentiation of multiple cells from both innate and adaptive immune systems. IL-15 up-regulation has a central role in the development of several autoimmune or chronic inflammatory...
| Schlagworte: | IL15, IL-15, Interleukin-15, Interleukin-15 |
| Anwendung: | Bioassays |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | ~14 kD |
ab 187,00 €
IL-6 (human) (rec.) (His)
Artikelnummer: CHI-HF-20106-C010
Interleukin 6 (IL-6) is a pleiotropic alpha-helical cytokine that plays important roles in acute phase reactions, inflammation, hematopoiesis, bone metabolism and cancer progression. IL-6 activity is essential for the transition from acute inflammation to either acquired immunity or chronic inflammatory disease. It...
| Schlagworte: | CDF, IL6, IL-6, BSF-2, IFNB2, IFN-beta-2, Interleukin-6, Interferon beta-2, Hybridoma growth factor, CTL differentiation... |
| Anwendung: | Bioassays |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | ~22 kD |
ab 132,00 €
IL-21 (mutant) (human) (rec.) (His)
Artikelnummer: CHI-HR-20021M-C010
Interleukin-21 (IL-21) is a key factor in the transition between innate and adaptive immune responses secreted by activated T cells. The IL-21 receptor (IL-21R) is expressed in lymphoid tissue, in particular by NK, B, T and dendritic cells, macrophages and endothelial cells. Recent evidence suggests that IL-21 plays...
| Schlagworte: | IL21, Za11, IL-21, Interleukin-21 |
| Anwendung: | Bioassays |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
ab 209,00 €
BMP-2, human recombinant (rHuBMP-2) (His)
Artikelnummer: CHI-HR-200BMP2-C010
The extracellular domain of human BMP-2 (aa 289-396) is fused at the C-terminus to a His-tag. Bone morphogenetic protein 2 (BMP-2) is a member of the BMP subgroup of the TGF-beta superfamily. It plays a dominant role in embryonic dorsalventral patterning, organogenesis, limb bud formation and bone formation and...
| Schlagworte: | BMP2, Bone Morphogenetic Protein 2 |
| Anwendung: | Bioassays |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
ab 209,00 €
IL-1alpha (human) (rec.)
Artikelnummer: CHI-HF-20001A-C010
The most prominent members of the interleukin-1 (IL-1) superfamily are IL-1alpha and IL-1beta. They lack a signal peptide and are secreted by an unconventional, endoplasmic reticulum-Golgi-independent mechanism. IL-1alpha was reported to be more widely and constitutively expressed and has intracellular functions,...
| Schlagworte: | IL1A, IL1F1, IL-1 alpha, Hematopoietin-1, Interleukin-1 alpha, Interleukin-1alpha, IL-1F1, IL-1A |
| Anwendung: | Bioassays |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | ~19 kD |
248,00 €
IL-21 (human) (rec.) (His)
Artikelnummer: CHI-HF-20121-C010
Interleukin-21 (IL-21) is a key factor in the transition between innate and adaptive immune responses secreted by activated T cells. The IL-21 receptor (IL-21R) is expressed in lymphoid tissue, in particular by NK, B, T and dendritic cells, macrophages and endothelial cells. Recent evidence suggests that IL-21 plays...
| Schlagworte: | IL21, Za11, IL-21, Interleukin-21, Interleukin-21 |
| Anwendung: | Bioassays |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | ~18 kD |
248,00 €
FLT3 Ligand (human) (rec.) (His)
Artikelnummer: CHI-HF-201FLT3L-C010
FMS-like tyrosine kinase 3 ligand (FLT3L) acts as a growth factor that increases the number of immune cells (lymphocytes (B cells and T cells)) by activating the hematopoietic progenitors. It binds to FLT3 (CD135) which is found on multipotent progenitor (MPP) and common lymphoid progenitor (CLP) cells in mice....
| Schlagworte: | Flt3L, FLT3LG, SL cytokine, Flt3 ligand, Fms-related tyrosine kinase 3 ligand, FLT3L, FMS-like Tyrosine Kinase 3 Ligand |
| Anwendung: | Bioassays |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | ~25 kD |
248,00 €
IL-10 (human): Fc (human) (rec.)
Artikelnummer: CHI-HF-21010-C010
Unfortunately, most cytokines have short circulating half-lives. With the creation of a group of new immunoglobulin- based cytokine fusion proteins, in which a cytokine sequence had been genetically fused to the hinge, CH2 and CH3 regions of an immunoglobulin, these cytokine fusion proteins possess both the...
| Schlagworte: | IL10, CSIF, IL-10, Interleukin-10, Cytokine synthesis inhibitory factor |
| Anwendung: | Bioassays |
| Exprimiert in: | Hamster cells |
| Ursprungsart: | human |
264,00 €