Produkte von Chimerigen Laboratories

Chimerigen

Chimerigen entwickelt und produziert einzigartige, Immunglobulin-basierte, chimäre Fusionsproteine und verwandte Forschungsprodukte mit Hilfe modernster zell- und molekularbiologischen Techniken. Diese Reagenzien werden erfolgreich in der biomedizinischen Grundlagen- und in angewandter Forschung eingesetzt.

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IL-10 (human) (rec.) (His)
IL-10 (human) (rec.) (His)

Artikelnummer: CHI-HF-20110-C010

Interleukin-10 (IL-10) is a cytokine produced by activated Th2 cells, B cells, keratinocytes and monocytes/macrophages. In vitro murine and human IL-10 inhibits cytokine synthesis by Th1 cells, natural killer cells and monocytes/macrophages. Several studies have suggested the potential application of IL-10 as an...
Schlagworte: IL10, CSIF, IL-10, Interleukin-10, Cytokine synthesis inhibitory factor, Interleukin-10, Cytokine Synthesis Inhibitory...
Anwendung: Bioassays
Exprimiert in: Human cells
Ursprungsart: human
MW: ~18 kD
248,00 €
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EGF (human) (rec.) (His)
EGF (human) (rec.) (His)

Artikelnummer: CHI-HF-201EGF-C010

Epidermal growth factor (EGF) is a growth factor and the founding member of the EGF family. All EGF family members are synthesized as type I transmembrane precursor proteins that may contain several EGF domains in the extracellular region. The mature proteins are released from the cell surface by regulated...
Schlagworte: EGF, Pro-Epidermal Growth Factor, HOMG4, URG
Anwendung: Bioassays
Exprimiert in: Human cells
Ursprungsart: human
MW: ~10 kD
209,00 €
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SCF (human):Fc (human) (rec.)
SCF (human):Fc (human) (rec.)

Artikelnummer: CHI-HF-210SCF-C010

The extracellular domain of human SCF (aa 26-187) is fused at the C-terminus to the Fc portion of human IgG1. Stem cell factor (SCF), also known as cKit ligand (KL), mast cell growth factor (MGF) and steel factor (SLF), is a widely expressed 28-40 kDa type I transmembrane glycoprotein. It promotes the survival,...
Schlagworte: Stem Cell Factor, c-Kit Ligand, Kit Ligand, Mast Cell Grow Factor, MGF
Anwendung: Bioassays
Exprimiert in: Hamster cells
Ursprungsart: human
187,00 €
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IL-4 (human):Fc (human) (rec.) (non-lytic)
IL-4 (human):Fc (human) (rec.) (non-lytic)

Artikelnummer: CHI-HF-22004-C010

The extracellular domain of human IL-4 (aa 25-153) is fused at the C-terminus to the Fc portion of a mutant human IgG1. Lyophilized from 0.2µm-filtered solution in PBS. Shows the biological function of the IL-4 moiety and exerts a prolonged circulating half-life caused by the modified Fc domain. Interleukin-4 (IL-4)...
Schlagworte: IL4, IL-4, BSF-1, Pitrakinra, Binetrakin, Interleukin-4, B-cell stimulatory factor 1, Lymphocyte stimulatory factor 1
Anwendung: Bioassays
Exprimiert in: Mouse cells
Ursprungsart: human
ab 248,00 €
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IL-10 (human) (rec.) (His)
IL-10 (human) (rec.) (His)

Artikelnummer: CHI-HR-20010-C010

Interleukin-10 (IL-10) is a cytokine produced by activated Th2 cells, B cells, keratinocytes and monocytes/macrophages. In vitro murine and human IL-10 inhibits cytokine synthesis by Th1 cells, natural killer cells and monocytes/macrophages. Several studies have suggested the potential application of IL-10 as an...
Schlagworte: IL10, CSIF, IL-10, Interleukin-10, Cytokine synthesis inhibitory factor, Interleukin-10, Cytokine Synthesis Inhibitory...
Anwendung: Bioassays
Exprimiert in: E.coli
Ursprungsart: human
248,00 €
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IL-22 (mouse):Fc (mouse) (rec.)
IL-22 (mouse):Fc (mouse) (rec.)

Artikelnummer: CHI-MF-11022-C025

The extracellular domain of mouse IL-22 (aa 34-179) is fused at the C-terminus to the Fc portion of mouse IgG2a. Lyophilized from 0.2µm-filtered solution in PBS. Interleukin-22 (IL-22), also known as IL-10 related T cell derived inducible factor (ILTIF) was initially identified as a gene induced by IL-9 in mouse T...
Schlagworte: Il22, Il22a, IL-22, IL-TIF, IL-22a, IL-TIF alpha, Interleukin-22, Interleukin-22a, IL-10-related T-cell-derived-inducible...
Anwendung: Bioassays
Exprimiert in: Hamster cells
Ursprungsart: mouse
ab 314,00 €
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IL-2 (mouse):Fc (mouse) (rec.) (non-lytic)
IL-2 (mouse):Fc (mouse) (rec.) (non-lytic)

Artikelnummer: CHI-MF-12002-C010

The extracellular domain of mouse IL-2 (aa 21-169) is fused at the C-terminus to the Fc portion of a mutant mouse IgG2a. Lyophilized from 0.2µm-filtered solution in PBS. Shows the biological function of the IL-2 moiety and exerts a prolonged circulating half-life caused by the modified Fc domain. Blocks diabetogenic...
Schlagworte: Il2, TCGF, IL-2, Interleukin-2, T-cell growth factor
Anwendung: Bioassays
Exprimiert in: Mouse cells
Ursprungsart: mouse
ab 248,00 €
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IL-21R (mouse):Fc (mouse) (rec.) (nonlytic)
IL-21R (mouse):Fc (mouse) (rec.) (nonlytic)

Artikelnummer: CHI-MF-12021R-C025

Interleukin-21 receptor (IL-21R) is a type I transmembrane glycoprotein within the class I cytokine receptor family, type 4 subfamily. Complex formation between IL-21R and the common gamma chain (gamma-c) is required for signaling. IL-21R is expressed mainly on B cells (highest on mature, activated, follicular and...
Schlagworte: Interleukin-21 Receptor, CD360, NILR
Anwendung: Bioassays
Exprimiert in: Hamster cells
Ursprungsart: mouse
209,00 €
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IL-4 (mouse) (rec.) (His)
IL-4 (mouse) (rec.) (His)

Artikelnummer: CHI-MR-10004-C010

Interleukin-4 (IL-4) is a cytokine produced by type 2 helper T cells, the Th2 cells. These cells tends to make a specific set of lymphokines including IL-4, IL-5, IL-6, IL-10, IL-13, IL-3 and GM-CSF and fail to produce IL-2, IFN-gamma, and lymphotoxin (TNF-beta). In addition, mast cells can produce IL-4. IL-4 exerts...
Schlagworte: Il4, Il-4, IL-4, BSF-1, Interleukin-4, IGG1 induction factor, B-cell growth factor 1, B-cell stimulatory factor 1,...
Anwendung: Bioassays
Exprimiert in: E.coli
Ursprungsart: mouse
ab 226,00 €
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IL-2 (rat) (rec.) (His)
IL-2 (rat) (rec.) (His)

Artikelnummer: CHI-RR-30002-C010

Protein function: Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells....
Schlagworte: Il2, TCGF, IL-2, Interleukin-2, T-cell growth factor
Anwendung: Bioassays
Exprimiert in: E.coli
Ursprungsart: rat
209,00 €
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IL-23 (human) (rec.)
IL-23 (human) (rec.)

Artikelnummer: CHI-AG-40A-0038-C010

Interleukin-23 (IL-23) is a heterodimeric cytokine and a member of the IL-12 family involved in innate and adaptive immunity. It is composed of the IL-12 p40 chain covalently linked to p19, a chain related to the IL-12 p35 subunit. IL-23 signals through the IL-23 receptor complex, which is composed of the...
Schlagworte: SGRF, IL23A, IL-23-A, IL-23p19, IL-23 subunit alpha, Interleukin-23 subunit p19, Interleukin-23 subunit alpha
Anwendung: Bioassays
Exprimiert in: Human cells
Ursprungsart: human
MW: ~70 kD
286,00 €
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IL-12 (human) (rec.) (His)
IL-12 (human) (rec.) (His)

Artikelnummer: CHI-HF-20112-C010

Interleukin-12 (IL-12), also known as Natural Killer Cell Stimulatory Factor (NKSF) or Cytotoxic Lymphocyte Maturation Factor (CLMF), is a heterodimeric pleiotropic cytokine made up of a 40 kDa (p40) subunit and a 35 kDa (p35) subunit. IL-12 is produced by macrophages and B lymphocytes and has been shown to have...
Schlagworte: IL12A, NKSF1, IL-12A, CLMF p35, IL-12 subunit p35, Interleukin-12 subunit alpha, NK cell stimulatory factor chain 1,...
Anwendung: Bioassays
Exprimiert in: Human cells
Ursprungsart: human
MW: ~85 kD
ab 248,00 €
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