Produkte von Chimerigen Laboratories
Chimerigen entwickelt und produziert einzigartige, Immunglobulin-basierte, chimäre Fusionsproteine und verwandte Forschungsprodukte mit Hilfe modernster zell- und molekularbiologischen Techniken. Diese Reagenzien werden erfolgreich in der biomedizinischen Grundlagen- und in angewandter Forschung eingesetzt.
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![CD272 [BTLA] (human):Fc (mouse) (rec.)](/custom/plugins/NetiThemeBiomol/Resources/Themes/Frontend/Biomol/frontend/_public/src/img/no-picture.jpg "CD272 [BTLA] (human):Fc (mouse) (rec.)")
CD272 [BTLA] (human):Fc (mouse) (rec.)
Artikelnummer: CHI-HF-211CD272-C100
BTLA is a type I transmembrane glycoprotein of the CD28 family of T cell costimulatory molecules. BTLA functions as a coinhibitor on activated T cells and on B cells and dendritic cells. The extracellular domain (ECD) of this Ig superfamily protein contains one V-type Ig-like domain, which interacts with HVEM.
| Schlagworte: | BTLA, CD272, B- and T-lymphocyte attenuator, B- and T-lymphocyte-associated protein, BTLA, B- and T-lymphocyte attenuator |
| Anwendung: | Bioassays |
| Exprimiert in: | Hamster cells |
| Ursprungsart: | human |
457,00 €
CD38 (human):Fc (mouse) (rec.)
Artikelnummer: CHI-HF-211CD38-C100
CD38, also known as cyclic ADP ribose hydrolase is a glycoprotein found on the surface of many immune cells (white blood cells), including CD4+, CD8+, B lymphocytes and natural killer cells. CD38 also functions in cell adhesion, signal transduction and calcium signaling.CD38 is a multifunctional ectoenzyme that...
| Schlagworte: | T10, CD38, ADPRC 1, EC=3.2.2.6, EC=2.4.99.20, cADPr hydrolase 1, ADP-ribosyl cyclase 1, Cyclic ADP-ribose hydrolase 1,... |
| Anwendung: | Bioassays |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | ~70 kD |
429,00 €
CD45 (human):Fc (mouse) (rec.)
Artikelnummer: CHI-HF-211CD45-C050
Protein tyrosine phosphatase, receptor type C (CD45), also known as PTPRC is a member of the protein tyrosine phosphatase (PTP) family which is known for its function to serve as signaling molecules and to regulate a variety of cellular processes such as cell proliferation, differentiation, mitotic cycle and...
| Schlagworte: | CD45, T200, L-CA, PTPRC, EC=3.1.3.48, Leukocyte common antigen, Receptor-type tyrosine-protein phosphatase C, LCA, LY5,... |
| Anwendung: | Bioassays |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | ~65 kD |
391,00 €
CD56 [NCAM] (human):Fc (mouse) (rec.)
Artikelnummer: CHI-HF-211CD56-C050
Human CD56 is an adhesion molecule from the Ig superfamily which is restricted to NK cells in the immune system. It is believed that NK cells form a first line of defense against tumor cells and cells infected with bacteria and viruses.
| Schlagworte: | CD56, NCAM, NCAM1, NCAM-1, N-CAM-1, Neural cell adhesion molecule 1, NCAM |
| Anwendung: | Bioassays |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | ~140 kD |
391,00 €
CD80 (human):Fc (mouse) (rec.)
Artikelnummer: CHI-HF-211CD80-C100
CD80 (B7-1) and CD86 (B7-2) together with their receptors CD28 and CTLA-4 constitute one of the dominant costimulatory pathways that regulate T cell and B cell responses. Although both CTLA-4 and CD28 can bind to the same ligands, CTLA-4 binds to B7-1 and B7-2 with a 20-100 fold higher affinity than CD28 and is...
| Schlagworte: | B7, BB1, CD80, CD28LG, Activation B7-1 antigen, CTLA-4 counter-receptor B7.1, T-lymphocyte activation antigen CD80, B7-1 |
| Anwendung: | Bioassays |
| Exprimiert in: | Hamster cells |
| Ursprungsart: | human |
429,00 €
CD86 (human):Fc (mouse) (rec.)
Artikelnummer: CHI-HF-211CD86-C100
CD86 (B7-2) is a 60-100 kDa variably glycosylated protein in the B7 family. B7 family members are transmembrane cell surface molecules that play important roles in immune activation and the maintenance of immune tolerance. B7-2 is highly expressed on activated antigen presenting cells (APC), e.g. B cells, dendritic...
| Schlagworte: | B70, BU63, CD86, FUN-1, CD28LG2, Activation B7-2 antigen, CTLA-4 counter-receptor B7.2, T-lymphocyte activation antigen... |
| Anwendung: | Bioassays |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
429,00 €
CD278 [ICOS] (human):Fc (mouse) (rec.)
Artikelnummer: CHI-HF-211ICOS-C100
CD278, also called inducible costimulator (ICOS) or CRP1 (CD28-related protein-1), is a member of the growing CD28 family of immune costimulatory receptors. Other family members are CD28, CTLA-4 and PD-1. ICOS is expressed on most CD45RO+ cells. ICOS expression is upregulated within approximately 24-48 hours of...
| Schlagworte: | ICOS, AILIM, CD278, Inducible T-cell costimulator, Activation-inducible lymphocyte immunomediatory molecule, ICOS,... |
| Anwendung: | Bioassays |
| Exprimiert in: | Hamster cells |
| Ursprungsart: | human |
429,00 €
CD279 [PD-1] (human):Fc (mouse) (rec.)
Artikelnummer: CHI-HF-211PD1-C100
CD279 (Programmed Cell Death Protein 1, PD-1) is a type I transmembrane protein belonging to the CD28/CTLA-4 family of immunoreceptors that mediate signals for regulating immune responses. Members of the CD28/CTLA-4 family have been shown to either promote T cell activation (CD28 and ICOS) or downregulate T cell...
| Schlagworte: | PD1, PDCD1, CD279, hPD-1, Protein PD-1, Programmed cell death protein 1, PD-1, Programmed Cell Death Protein 1 |
| Anwendung: | Bioassays |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | ~60 kD |
429,00 €
CD274 [B7-H1/PD-L1] (human):Fc (mouse) (rec.)
Artikelnummer: CHI-HF-211PDL1-C100
Programmed death ligand 1 (PD-L1, B7-H1 or CD274) is a member of the growing B7 family of immune proteins that provide signals for both stimulating and inhibiting T cell activation. CD274 has been identified as one of two ligands for programmed death 1 (PD-1), a member of the CD28 family of immunoreceptors. CD274 is...
| Schlagworte: | B7H1, CD274, B7-H1, PD-L1, B7 homolog 1, PDCD1 ligand 1, Programmed death ligand 1, Programmed cell death 1 ligand 1,... |
| Anwendung: | Bioassays |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | ~70 kD |
429,00 €
CD273 [PD-L2] (human):Fc (mouse) (rec.)
Artikelnummer: CHI-HF-211PDL2-C100
T cells require a signal induced by the engagement of the T cell receptor and a costimulatory signal(s) through distinct T cell surface molecules for optimal T cell activation and tolerance. CD273 (PD-L2) is one of two ligands for programmed death-1 (PD-1, CD279), a member of the CD28 family of immunoreceptors. The...
| Schlagworte: | B7DC, PD-L2, CD273, B7-DC, PDCD1LG2, PD-1 ligand 2, PDCD1 ligand 2, Butyrophilin B7-DC, Programmed death ligand 2,... |
| Anwendung: | Bioassays |
| Exprimiert in: | Hamster cells |
| Ursprungsart: | human |
429,00 €
SCF (human):Fc (mouse) (rec.)
Artikelnummer: CHI-HF-211SCF-C050
The extracellular domain of human SCF (aa 26-187) is fused at the C-terminus to the Fc portion of a mutant mouse IgG2a. Lyophilized from 0.2µm-filtered solution in PBS. Stem cell factor (SCF), also known as cKit ligand (KL), mast cell growth factor (MGF), and steel factor (SLF), is a widely expressed 28-40 kDa type...
| Schlagworte: | MGF, SCF, KITLG, sKITLG, Kit ligand, c-Kit ligand, Stem cell factor, Soluble KIT ligand, Mast cell growth factor |
| Anwendung: | Bioassays |
| Exprimiert in: | Hamster cells |
| Ursprungsart: | human |
314,00 €
Tim-1 (human):Fc (mouse) (rec.)
Artikelnummer: CHI-HF-211T1-C100
The TIM (T cell/transmembrane, immunoglobulin and mucin) family plays a critical role in regulating immune responses, including allergy, asthma, transplant tolerance, autoimmunity and the response to viral infections. The unique structure of TIM immunoglobulin variable region domains allows highly specific...
| Schlagworte: | TIM, KIM1, KIM-1, TIM-1, TIMD-1, HAVCR1, HAVcr-1, Kidney injury molecule 1, T-cell membrane protein 1, Hepatitis A virus... |
| Anwendung: | Bioassays |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | ~110 kD |
523,00 €