Produkte von Chimerigen Laboratories
Chimerigen entwickelt und produziert einzigartige, Immunglobulin-basierte, chimäre Fusionsproteine und verwandte Forschungsprodukte mit Hilfe modernster zell- und molekularbiologischen Techniken. Diese Reagenzien werden erfolgreich in der biomedizinischen Grundlagen- und in angewandter Forschung eingesetzt.
Mehr Informationen unter: www.adipogen.com/chimerigen
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IL-10Ralpha (human):Fc (human) (rec.)
Artikelnummer: CHI-HF-21010RA-C050
CD210, also known as IL10RA, is a subunit for the interleukin-10 receptor. IL10RA has also been designated CDW210A (cluster of differentiation W210A). It is structurally related to interferon receptors. CD210 has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of...
| Schlagworte: | IL10R, CD210, IL10RA, IL-10R1, CDw210a, IL-10RA, IL-10R subunit 1, IL-10R subunit alpha, IL-10 receptor subunit alpha,... |
| Anwendung: | Bioassays |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | ~70 kD |
391,00 €
IL-12 (human):Fc (human) (rec.)
Artikelnummer: CHI-HF-21012-C025
Interleukin-12 (IL-12), also known as Natural Killer Cell Stimulatory Factor (NKSF) or Cytotoxic Lymphocyte Maturation Factor (CLMF), is a heterodimeric pleiotropic cytokine made up of a 40 kDa (p40) subunit and a 35 kDa (p35) subunit. IL-12 is produced by macrophages and B lymphocytes and has been shown to have...
| Schlagworte: | IL12A, NKSF1, IL-12A, CLMF p35, IL-12 subunit p35, Interleukin-12 subunit alpha, NK cell stimulatory factor chain 1,... |
| Anwendung: | Bioassays |
| Exprimiert in: | Hamster cells |
| Ursprungsart: | human |
468,00 €
IL-15 (mutant) (human):Fc (human) (rec.)
Artikelnummer: CHI-HF-21015M-C050
The extracellular domain of human IL-15 (aa 20-359) including mutations at Q148D and Q156D is fused at the C-terminus to the Fc portion of human IgG1. Lyophilized from 0.2µm-filtered solution in PBS. This mutant IL-15/Fc fusion protein specifically binds to the IL-15R, competitively inhibits IL-15-triggered cell...
| Schlagworte: | IL15, IL-15, Interleukin-15 |
| Anwendung: | Bioassays |
| Exprimiert in: | Hamster cells |
| Ursprungsart: | human |
484,00 €
IL-23R (human):Fc (human) (rec.)
Artikelnummer: CHI-HF-21023R-C100
Interleukin-23 receptor (IL-23R), is a member of the type I cytokine receptor family, type 2 subfamily. It is expressed by monocytes, Th1, Th0, NK and dendritic cells. Isoform 1 is specifically expressed in NK cells. IL-23 functions in innate and adaptive immunity and may participate in acute response to infection...
| Schlagworte: | IL23R, IL-23R, IL-23 receptor, Interleukin-23 receptor, Interleukin-23 Receptor |
| Anwendung: | Bioassays |
| Exprimiert in: | Hamster cells |
| Ursprungsart: | human |
418,00 €
IL-24 (human):Fc (human) (rec.)
Artikelnummer: CHI-HF-21024-C025
IL-24 is a cytokine belonging to the IL-10 family of cytokines that signals through two heterodimeric receptors: IL-20R1/IL-20R2 and IL-22R1/IL-20R2. This interleukin is also known as melanoma differentiation-associated 7 (mda-7) due to its discovery as a tumour suppressing protein. IL-24 appears to control cell...
| Schlagworte: | MDA7, IL24, MDA-7, IL-24, Interleukin-24, Suppression of tumorigenicity 16 protein, Melanoma differentiation-associated... |
| Anwendung: | Bioassays |
| Exprimiert in: | Hamster cells |
| Ursprungsart: | human |
468,00 €
IL-27 (human): Fc (human) (rec.)
Artikelnummer: CHI-HF-21027-C050
Unfortunately, most cytokines have short circulating half-lives. With the creation of a group of new immunoglobulin- based cytokine fusion proteins, in which a cytokine sequence had been genetically fused to the hinge, CH2 and CH3 regions of an immunoglobulin, these cytokine fusion proteins possess both the...
| Schlagworte: | p28, IL27, IL27A, IL27-A, IL-27-A, IL-27 subunit alpha, Interleukin-27 subunit alpha, EBI3, IL27B, IL-27B, IL-27 subunit... |
| Anwendung: | Bioassays |
| Exprimiert in: | Hamster cells |
| Ursprungsart: | human |
457,00 €
IL-33 (human):Fc (human) (rec.)
Artikelnummer: CHI-HF-21033-C050
Interleukin-33 (IL-33, HF-NEV, IL-1F11), a member of the IL-1 family of cytokines, is expressed by many cell types following pro-inflammatory stimulation and is thought to be released upon cell lysis. IL33 binds to and signals through ST2 (IL1R1) and its stimulation recruits MYD88, IRAK, IRAK4, and TRAF6, followed...
| Schlagworte: | IL33, C9orf26, Interleukin-33, IL-1F11, NF-HEV |
| Anwendung: | Bioassays |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | ~50 kD |
391,00 €
CD152 [CTLA-4] (human):Fc (human) (rec.)
Artikelnummer: CHI-HF-210A4-C100
The extracellular domain of human CD152 [CTLA-4] is fused at the C-terminus to the Fc portion of human IgG1. Lyophilized from 0.2µm-filtered solution in PBS. Binds both CD80 (B7-1) and CD86 (B7-2) with high affinity and inhibits CD28 signaling competitively. Kills the target cell completely. CD152 [CTLA-4] and CD28,...
| Schlagworte: | CTLA4, CD152, CTLA-4, Cytotoxic T-lymphocyte protein 4, Cytotoxic T-lymphocyte-associated antigen 4 |
| Anwendung: | Bioassays |
| Exprimiert in: | Mouse cells |
| Ursprungsart: | human |
ab 121,00 €
CD275 [B7-H2] (human):Fc (human) (rec.)
Artikelnummer: CHI-HF-210B7H2-C100
The extracellular domain of human CD275 [B7-H2] (aa 1-256) is fused to the N-terminus of the Fc region of human IgG1.
| Schlagworte: | B7H2, B7-H2, CD275, B7RP-1, ICOSLG, ICOS ligand, B7 homolog 2, B7-like protein Gl50, B7-related protein 1 |
| Anwendung: | Stimulator of human T cell proliferation in the presence of anti-CD3 |
| Exprimiert in: | Hamster cells |
| Ursprungsart: | human |
429,00 €
B7-H4 (human):Fc (human) (rec.)
Artikelnummer: CHI-HF-210B7H4-C100
The extracellular domain of human B7-H4 (aa 29-258) is fused to the N-terminus of the Fc region of human IgG1. Lyophilized from 0.2µm-filtered solution in PBS. B7H4 is a B7 family member that negatively regulates T cell immunity by inhibiting of T cell proliferation, cytokine production, and cell cycle progression....
| Schlagworte: | B7h.5, Protein B7S1, T-cell costimulatory molecule B7x, Immune costimulatory protein B7-H4, V-set domain-containing T-cell... |
| Anwendung: | Bioassays |
| Exprimiert in: | Hamster cells |
| Ursprungsart: | human |
457,00 €
CCL20 (human):Fc (human) (rec.)
Artikelnummer: CHI-HF-210CCL20-C050
Macrophage Inflammatory Protein-3 (MIP3A) or Chemokine (C-C motif) ligand 20 (CCL20) or liver activation regulated chemokine (LARC) or is a small cytokine belonging to the CC chemokine family that attracts immature dendritic cells and memory T lymphocytes, both expressing CCR6. Depending on the cell type, this...
| Schlagworte: | LARC, CCL20, Chemokine (C-C motif) ligand 20, LARC, MIP-3A, ST38, Scya20, Exodus-1 |
| Anwendung: | Bioassays |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | ~38 kD |
369,00 €
CD134 [OX40] (human):Fc (human) (rec.)
Artikelnummer: CHI-HF-210CD134-C050
CD134 (OX40) is a T cell activation antigen structurally belonging to a lymphocyte-specific subgroup of the nerve growth factor and tumor necrosis factor receptor superfamily, which also includes the T cell antigen CD27, B cell antigen CD40, FAS antigen and the T cell activation antigen 4-1BB. The human CD134...
| Schlagworte: | CD134, TXGP1L, TNFRSF4, ACT35 antigen, OX40L receptor, Tumor necrosis factor receptor superfamily member 4, TAX... |
| Anwendung: | Bioassays |
| Exprimiert in: | Hamster cells |
| Ursprungsart: | human |
380,00 €