Produkte von Chimerigen Laboratories

Chimerigen

Chimerigen entwickelt und produziert einzigartige, Immunglobulin-basierte, chimäre Fusionsproteine und verwandte Forschungsprodukte mit Hilfe modernster zell- und molekularbiologischen Techniken. Diese Reagenzien werden erfolgreich in der biomedizinischen Grundlagen- und in angewandter Forschung eingesetzt.

Mehr Informationen unter: www.adipogen.com/chimerigen

Zu den Katalogen von Chimerigen Laboratories

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CD279 [PD-1] (mouse):Fc (mouse) (rec.)
CD279 [PD-1] (mouse):Fc (mouse) (rec.)

Artikelnummer: CHI-MF-110PD1-C100

The extracellular domain of mouse CD279 [PD-1] (aa 26-169) is fused to the N-terminus of the Fc region of mouse IgG2a. CD279 (Programmed Cell Death Protein 1, PD-1) is a type I transmembrane protein belonging to the CD28/CTLA-4 family of immunoreceptors that mediate signals for regulating immune responses. Members...
Schlagworte: Pd1, CD279, mPD-1, Pdcd1, Protein PD-1, Programmed cell death protein 1
Anwendung: Bioassays
Exprimiert in: Hamster cells
Ursprungsart: mouse
429,00 €
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Semaphorin-4A (mouse):Fc (human) (rec.)
Semaphorin-4A (mouse):Fc (human) (rec.)

Artikelnummer: CHI-MF-111SEMA4-C100

The extracellular domain of mouse Semaphorin-4A (aa 1-676) is fused at the C-terminus to the Fc portion of human IgG1. Lyophilized from 0.2µm-filtered solution in PBS. Semaphorin 4A (Sema4A, previously semB) is a Class 4 transmembrane Semaphorin with activity in the immune and nervous systems. Sema4A was first...
Schlagworte: Semab, Sema4a, Sema B, Semaphorin-B, Semaphorin-4A
Anwendung: Bioassays
Exprimiert in: Hamster cells
Ursprungsart: mouse
512,00 €
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Fc (mouse) IgG2a Control (rec.) (non-lytic)
Fc (mouse) IgG2a Control (rec.) (non-lytic)

Artikelnummer: CHI-MF-120IG2A-C100

This product should be used as the control protein for activity tests of fusion proteins including mouse target proteins and mouse IgG2a-Fc domains.
Schlagworte: Ighg, Ig gamma-2A chain C region, A allele, Immunoglobulin heavy chain gamma polypeptide,
Anwendung: Bioassays
Exprimiert in: Human cells
Ursprungsart: mouse
MW: ~26 kD
391,00 €
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CD274 [B7-H1/PD-L1] (mouse):Fc (mouse) (rec.) (non-lytic)
CD274 [B7-H1/PD-L1] (mouse):Fc (mouse) (rec.) (non-lytic)

Artikelnummer: CHI-MF-120PDL1-C100

The extracellular domain of mouse CD274 [B7-H1] (aa 19-237) is fused to the N-terminus of the Fc region of a mutant mouse IgG2a. Lyophilized from 0.2µm-filtered solution in PBS. Shows the biological function of the CD274 moiety and exerts a prolonged circulating half-life caused by the modified Fc domain. Programmed...
Schlagworte: B7h1, B7-H1, Cd274, PD-L1, CD274, B7 homolog 1, PDCD1 ligand 1, Programmed death ligand 1, Programmed cell death 1 ligand 1
Anwendung: Bioassays
Exprimiert in: Hamster cells
Ursprungsart: mouse
429,00 €
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SCF (mouse):Fc (mouse) (rec.) (non-lytic)
SCF (mouse):Fc (mouse) (rec.) (non-lytic)

Artikelnummer: CHI-MF-120SCF-C050

The extracellular domain of mouse SCF (aa 26-214) is fused at the C-terminus to the Fc portion of a mutant mouse IgG2a. Lyophilized from 0.2µm-filtered solution in PBS. Shows the biological function of the SCF moiety and exerts a prolonged circulating half-life caused by the modified Fc domain. Stem cell factor...
Schlagworte: MGF, SCF, Kitl, Kitlg, sKITLG, Kit ligand, c-Kit ligand, Steel factor, Stem cell factor, Soluble KIT ligand, Mast cell...
Anwendung: Bioassays
Exprimiert in: Hamster cells
Ursprungsart: mouse
314,00 €
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HMGB1 (rat) (rec.) (His)
HMGB1 (rat) (rec.) (His)

Artikelnummer: CHI-RR-300HMGB1-C025

HMGB1 was originally discovered as an essential DNA-binding protein for regulating p53, NF-kappaB and other important proteins. It is secreted from activated dentric cells, macrophage and nectrotic cells, and acts as a ligand for RAGE, TLR-2 and TLR-4 expressed on surrounding cells. As a result, HMGB1 activates Rac,...
Schlagworte: HMG-1, Hmgb1, Amphoterin, Heparin-binding protein p30, High mobility group protein 1, High mobility group protein B1
Anwendung: Bioassays
Exprimiert in: E.coli
Ursprungsart: rat
341,00 €
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IL-22 (human):Fc (human) (rec.)
IL-22 (human):Fc (human) (rec.)

Artikelnummer: CHI-HF-21022-C025

The extracellular domain of human IL-22 (aa 34-179) is fused at the C-terminus to the Fc portion of human IgG1. Lyophilized from 0.2µm-filtered solution in PBS. Interleukin-22 (IL-22), also known as IL-10 related T cell derived inducible factor (ILTIF) was initially identified as a gene induced by IL-9 in mouse T...
Schlagworte: IL22, IL-22, ILTIF, IL-TIF, Interleukin-22, Cytokine Zcyto18, IL-10-related T-cell-derived-inducible factor
Anwendung: Bioassays
Exprimiert in: Hamster cells
Ursprungsart: human
314,00 €
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IL-1beta (human) (rec.) (His)
IL-1beta (human) (rec.) (His)

Artikelnummer: CHI-HR-20001B-C010

IL-1beta is produced by activated macrophages. IL-1beta stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1beta belongs to the IL-1 family of proteins that are involved in the inflammatory response. IL-1beta in most situations...
Schlagworte: IL1B, IL1F2, IL-1 beta, Catabolin, Interleukin-1 beta
Anwendung: Bioassays
Exprimiert in: E.coli
Ursprungsart: human
ab 248,00 €
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IFN-gamma (human) (rec.) (His)
IFN-gamma (human) (rec.) (His)

Artikelnummer: CHI-HR-200IFNG-C010

IFN gamma, also known as IFNG, is a secreted protein which belongs to the type I I interferon family. IFN gamma is produced predominantly by natural killer and natural killer T cells as part of the innate immune response, and by CD4 and CD8 cytotoxic T lymphocyte effector T cells once antigen-specific immunity...
Schlagworte: IFNG, IFN-gamma, Interferon gamma, Immune interferon, Interferon-gamma IFNG
Anwendung: Bioassays
Exprimiert in: E.coli
Ursprungsart: human
MW: ~17 kD
ab 132,00 €
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IL-8 (human):Fc (human) (rec.) (nonlytic)
IL-8 (human):Fc (human) (rec.) (nonlytic)

Artikelnummer: CHI-HF-22008-C050

Unfortunately, most cytokines have short circulating half-lives. With the creation of a group of new immunoglobulin- based cytokine fusion proteins, in which a cytokine sequence had been genetically fused to the hinge, CH2 and CH3 regions of an immunoglobulin, these cytokine fusion proteins possess both the...
Schlagworte: Interleukin-8, CXCL8, C-X-C Motif Chemokine 8, Emoctakin, GCP-1, LAI, MDNCF, MONAP, NAP-1, NCF, TCF
Anwendung: Bioassays
Exprimiert in: Hamster cells
Ursprungsart: human
ab 171,00 €
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Interleukin-4, human recombinant (rHuIL-4) (His)
Interleukin-4, human recombinant (rHuIL-4) (His)

Artikelnummer: CHI-HR-20004-C010

Interleukin-4 (IL-4) is a cytokine produced by type 2 helper T cells, the Th2 cells. These cells tends to make a specific set of lymphokines including IL-4, IL-5, IL-6, IL-10, IL-13, IL-3 and GM-CSF and fail to produce IL-2, IFN-gamma, and lymphotoxin (TNF-beta). In addition, mast cells can produce IL-4. IL-4 exerts...
Schlagworte: BCGF, BCDF, B cell stimulating factor, BSF-1, Lymphocyte stimulatory factor 1, IL-4, MGC79402, Binetrakin, Pitrakinra
Anwendung: Bioassays
Exprimiert in: E.coli
Ursprungsart: human
226,00 €
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COVID-19 Forschung
SARS-CoV-2 Nucleocapsid Protein (rec.) (His)
SARS-CoV-2 Nucleocapsid Protein (rec.) (His)

Artikelnummer: CHI-B233501-C100

Accession Number: QHD43423.2. SARS-CoV-2 Nucleocapsid protein (aa 1-419) is fused at the N-terminus to a His-tag. Endotoxin Content: <1EU/µg purified protein (LAL test). SARS-CoV-2 shares 79.5% sequence identity with SARS-CoV and is 96.2% identical at the genome level to the bat coronavirus BatCoV RaTG133,...
Schlagworte: 2019-nCoV N Protein
Exprimiert in: E.coli
Ursprungsart: SARS-CoV-2
341,00 €
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