Produkte von Chimerigen Laboratories
Chimerigen entwickelt und produziert einzigartige, Immunglobulin-basierte, chimäre Fusionsproteine und verwandte Forschungsprodukte mit Hilfe modernster zell- und molekularbiologischen Techniken. Diese Reagenzien werden erfolgreich in der biomedizinischen Grundlagen- und in angewandter Forschung eingesetzt.
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CD200 (mouse):Fc (mouse) (rec.) (non-lytic)
Artikelnummer: CHI-MF-120CD200-C050
The extracellular domain of mouse CD200 (aa 31-236) is fused at the C-terminus to the Fc portion of a mutant mouse IgG2a. Lyophilized from 0.2µm-filtered solution in PBS. CD200, also known as OX-2, is a 45 kDa transmembrane immunoregulatory protein that belongs to the immunoglobulin superfamily. CD200 is widely but...
| Schlagworte: | Mox2, CD200, Cd200, MRC OX-2 antigen, OX-2 membrane glycoprotein |
| Anwendung: | Bioassays |
| Exprimiert in: | Hamster cells |
| Ursprungsart: | mouse |
391,00 €
CD54 [ICAM-1] (mouse):Fc (mouse) (rec.) (non-lytic)
Artikelnummer: CHI-MF-120ICAM1-C050
The extracellular domain of mouse CD54 [ICAM-1] (aa 28-485) is fused at the C-terminus to the Fc portion of a mutant mouse IgG2a. Lyophilized from 0.2µm-filtered solution in PBS. Shows the biological function of the CD54 moiety and exerts a prolonged circulating half-life caused by the modified Fc domain....
| Schlagworte: | CD54, MyD10, Icam1, MALA-2, ICAM-1, Intercellular adhesion molecule 1 |
| Anwendung: | Bioassays |
| Exprimiert in: | Hamster cells |
| Ursprungsart: | mouse |
248,00 €
HMGB1 (rat):Fc (human) (rec.) (rec.)
Artikelnummer: CHI-RF-311HMGB1-C050
The extracellular domain of rat HMGB1 (aa 24-215) is fused at the C-terminus to the Fc portion of human IgG1. Lyophilized from 0.2µm-filtered solution in PBS. HMGB1 was originally discovered as an essential DNA-binding protein for regulating p53, NF-kappaB and other important proteins. It is secreted from activated...
| Schlagworte: | HMG-1, Hmgb1, Amphoterin, Heparin-binding protein p30, High mobility group protein 1, High mobility group protein B1 |
| Anwendung: | Bioassays |
| Exprimiert in: | Hamster cells |
| Ursprungsart: | Rat |
512,00 €
IL-2 (human) (rec.) (His)
Artikelnummer: CHI-HF-20102-C010
Interleukin-2 (IL-2) is a 133 amino acid glycoprotein with one intramolecular disulfide bond and variable glycosylation. It is secreted by activated T cells and induces proliferation and maturation of activated T cells, natural killer cells, and lymphokine activated killer cells. IL-2 also stimulates proliferation...
| Schlagworte: | IL2, IL-2, TCGF, Aldesleukin, Interleukin-2, T-cell growth factor, Interleukin-2, Aldesleukin |
| Anwendung: | Bioassays |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | ~19 kD |
209,00 €
IL-10 (human) (rec.) (His)
Artikelnummer: CHI-HF-20110-C010
Interleukin-10 (IL-10) is a cytokine produced by activated Th2 cells, B cells, keratinocytes and monocytes/macrophages. In vitro murine and human IL-10 inhibits cytokine synthesis by Th1 cells, natural killer cells and monocytes/macrophages. Several studies have suggested the potential application of IL-10 as an...
| Schlagworte: | IL10, CSIF, IL-10, Interleukin-10, Cytokine synthesis inhibitory factor, Interleukin-10, Cytokine Synthesis Inhibitory... |
| Anwendung: | Bioassays |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | ~18 kD |
248,00 €
EGF (human) (rec.) (His)
Artikelnummer: CHI-HF-201EGF-C010
Epidermal growth factor (EGF) is a growth factor and the founding member of the EGF family. All EGF family members are synthesized as type I transmembrane precursor proteins that may contain several EGF domains in the extracellular region. The mature proteins are released from the cell surface by regulated...
| Schlagworte: | EGF, Pro-Epidermal Growth Factor, HOMG4, URG |
| Anwendung: | Bioassays |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | ~10 kD |
209,00 €
SCF (human):Fc (human) (rec.)
Artikelnummer: CHI-HF-210SCF-C010
The extracellular domain of human SCF (aa 26-187) is fused at the C-terminus to the Fc portion of human IgG1. Stem cell factor (SCF), also known as cKit ligand (KL), mast cell growth factor (MGF) and steel factor (SLF), is a widely expressed 28-40 kDa type I transmembrane glycoprotein. It promotes the survival,...
| Schlagworte: | Stem Cell Factor, c-Kit Ligand, Kit Ligand, Mast Cell Grow Factor, MGF |
| Anwendung: | Bioassays |
| Exprimiert in: | Hamster cells |
| Ursprungsart: | human |
187,00 €
IL-4 (human):Fc (human) (rec.) (non-lytic)
Artikelnummer: CHI-HF-22004-C010
The extracellular domain of human IL-4 (aa 25-153) is fused at the C-terminus to the Fc portion of a mutant human IgG1. Lyophilized from 0.2µm-filtered solution in PBS. Shows the biological function of the IL-4 moiety and exerts a prolonged circulating half-life caused by the modified Fc domain. Interleukin-4 (IL-4)...
| Schlagworte: | IL4, IL-4, BSF-1, Pitrakinra, Binetrakin, Interleukin-4, B-cell stimulatory factor 1, Lymphocyte stimulatory factor 1 |
| Anwendung: | Bioassays |
| Exprimiert in: | Mouse cells |
| Ursprungsart: | human |
ab 248,00 €
IL-10 (human) (rec.) (His)
Artikelnummer: CHI-HR-20010-C010
Interleukin-10 (IL-10) is a cytokine produced by activated Th2 cells, B cells, keratinocytes and monocytes/macrophages. In vitro murine and human IL-10 inhibits cytokine synthesis by Th1 cells, natural killer cells and monocytes/macrophages. Several studies have suggested the potential application of IL-10 as an...
| Schlagworte: | IL10, CSIF, IL-10, Interleukin-10, Cytokine synthesis inhibitory factor, Interleukin-10, Cytokine Synthesis Inhibitory... |
| Anwendung: | Bioassays |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
248,00 €
IL-22 (mouse):Fc (mouse) (rec.)
Artikelnummer: CHI-MF-11022-C025
The extracellular domain of mouse IL-22 (aa 34-179) is fused at the C-terminus to the Fc portion of mouse IgG2a. Lyophilized from 0.2µm-filtered solution in PBS. Interleukin-22 (IL-22), also known as IL-10 related T cell derived inducible factor (ILTIF) was initially identified as a gene induced by IL-9 in mouse T...
| Schlagworte: | Il22, Il22a, IL-22, IL-TIF, IL-22a, IL-TIF alpha, Interleukin-22, Interleukin-22a, IL-10-related T-cell-derived-inducible... |
| Anwendung: | Bioassays |
| Exprimiert in: | Hamster cells |
| Ursprungsart: | mouse |
ab 314,00 €
IL-2 (mouse):Fc (mouse) (rec.) (non-lytic)
Artikelnummer: CHI-MF-12002-C010
The extracellular domain of mouse IL-2 (aa 21-169) is fused at the C-terminus to the Fc portion of a mutant mouse IgG2a. Lyophilized from 0.2µm-filtered solution in PBS. Shows the biological function of the IL-2 moiety and exerts a prolonged circulating half-life caused by the modified Fc domain. Blocks diabetogenic...
| Schlagworte: | Il2, TCGF, IL-2, Interleukin-2, T-cell growth factor |
| Anwendung: | Bioassays |
| Exprimiert in: | Mouse cells |
| Ursprungsart: | mouse |
ab 248,00 €
IL-21R (mouse):Fc (mouse) (rec.) (nonlytic)
Artikelnummer: CHI-MF-12021R-C025
Interleukin-21 receptor (IL-21R) is a type I transmembrane glycoprotein within the class I cytokine receptor family, type 4 subfamily. Complex formation between IL-21R and the common gamma chain (gamma-c) is required for signaling. IL-21R is expressed mainly on B cells (highest on mature, activated, follicular and...
| Schlagworte: | Interleukin-21 Receptor, CD360, NILR |
| Anwendung: | Bioassays |
| Exprimiert in: | Hamster cells |
| Ursprungsart: | mouse |
209,00 €