Produkte von Chimerigen Laboratories
Chimerigen entwickelt und produziert einzigartige, Immunglobulin-basierte, chimäre Fusionsproteine und verwandte Forschungsprodukte mit Hilfe modernster zell- und molekularbiologischen Techniken. Diese Reagenzien werden erfolgreich in der biomedizinischen Grundlagen- und in angewandter Forschung eingesetzt.
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Tim-4 (mouse):Fc (mouse) (rec.)
Artikelnummer: CHI-MF-110T4-C100
Mouse T cell immunoglobulin and mucin domain-containing protein 4, also known as T cell membrane protein 4, TIMD4 and TIM4 is a single-pass type I membrane protein which belongs to the immunoglobulin superfamily and TIM family. TIM4 contains one Ig-like V-type (immunoglobulin-like) domain. It is expressed on...
| Schlagworte: | Tim4, Timd4, TIM-4, TIMD-4, SMUCKLER, T-cell membrane protein 4, T-cell immunoglobulin mucin receptor 4, Spleen,... |
| Anwendung: | Bioassays |
| Exprimiert in: | Human cells |
| Ursprungsart: | mouse |
| MW: | ~85 kD |
523,00 €
IL-12 (mouse):Fc (human) (rec.) (rec.)
Artikelnummer: CHI-MF-11112-C025
The mouse IL-12 complex composed of the p40 subunit (aa 1-335) and the p35 subunit (aa 23-215) is fused through a polypeptide linker to the Fc portion of human IgG1. Lyophilized from 0.2µm-filtered solution in PBS. Interleukin-12 (IL-12), also known as Natural Killer Cell Stimulatory Factor (NKSF) or Cytotoxic...
| Schlagworte: | Il12a, IL-12A, CLMF p35, IL-12 subunit p35, Interleukin-12 subunit alpha, Cytotoxic lymphocyte maturation factor 35 kDa... |
| Anwendung: | Bioassays |
| Exprimiert in: | Hamster cells |
| Ursprungsart: | mouse |
468,00 €
IL-27 (mouse):Fc (human) (rec.)
Artikelnummer: CHI-MF-11127-C050
The mouse IL-27 complex composed of the Ebi3 subunit (aa 1-228) and the p28 subunit (aa 29-234) is fused through a polypeptide linker to the Fc portion of human IgG1. Lyophilized from 0.2µm-filtered solution in PBS. Interleukin-27 (IL-27) is a heterodimeric group 2 receptor ligand molecule that belongs to the...
| Schlagworte: | Interleukin-27, Ebi3, Il17b, IL-27B, IL-27 subunit beta, Interleukin-27 subunit beta, Epstein-Barr virus-induced gene 3... |
| Anwendung: | Bioassays |
| Exprimiert in: | Hamster cells |
| Ursprungsart: | mouse |
468,00 €
CD134 [OX40] (mouse):Fc (human) (rec.)
Artikelnummer: CHI-MF-111CD134-C100
CD134 (OX40) is a T cell activation antigen structurally belonging to a lymphocyte-specific subgroup of the nerve growth factor and tumor necrosis factor receptor superfamily, which also includes the T cell antigen CD27, B cell antigen CD40, FAS antigen and the T cell activation antigen 4-1BB. The human CD134...
| Schlagworte: | Ox40, CD134, Tnfrsf4, OX40 antigen, OX40L receptor, Tumor necrosis factor receptor superfamily member 4, OX40, Tumor... |
| Anwendung: | Bioassays |
| Exprimiert in: | Human cells |
| Ursprungsart: | mouse |
| MW: | ~68 kD |
429,00 €
CD279 [PD-1] (mouse):Fc (human) (rec.)
Artikelnummer: CHI-MF-111PD1-C100
CD279 (Programmed Cell Death Protein 1, PD-1) is a type I transmembrane protein belonging to the CD28/CTLA-4 family of immunoreceptors that mediate signals for regulating immune responses. Members of the CD28/CTLA-4 family have been shown to either promote T cell activation (CD28 and ICOS) or downregulate T cell...
| Schlagworte: | Pd1, mPD-1, CD279, Pdcd1, Protein PD-1, Programmed cell death protein 1 |
| Anwendung: | Bioassays |
| Exprimiert in: | Human cells |
| Ursprungsart: | mouse |
| MW: | 42 kD |
429,00 €
Tim-1 (mouse):Fc (human) (rec.)
Artikelnummer: CHI-MF-111T1-C100
The extracellular domain of mouse Tim-1 (aa 22-212) is fused to the N-terminus of the Fc region of human IgG1. Tim-1 protein function: May play a role in T-helper cell development and the regulation of asthma and allergic diseases. Receptor for TIMD4. May play a role in kidney injury and repair. [The UniProt...
| Schlagworte: | Kim1, TIM-1, KIM-1, Havcr1, TIMD-1, HAVcr-1, Kidney injury molecule 1, T cell membrane protein 1, T-cell immunoglobulin... |
| Exprimiert in: | Hamster cells |
| Ursprungsart: | mouse |
523,00 €
Tim-2 (mouse):Fc (human) (rec.)
Artikelnummer: CHI-MF-111T2-C100
Probable receptor for SEMA4A involved in the regulation of T-cell function. The interaction with SEMA4A enhances T-cell activation.
| Schlagworte: | Tim2, TIM-2, Timd2, TIMD-2, T-cell membrane protein 2, T-cell immunoglobulin mucin receptor 2, T-cell immunoglobulin and... |
| Anwendung: | Bioassays |
| Exprimiert in: | Human cells |
| Ursprungsart: | mouse |
| MW: | ~65 kD |
523,00 €
Tim-4 (mouse):Fc (human) (rec.)
Artikelnummer: CHI-MF-111T4-C100
The extracellular domain of mouse Tim-4 (aa 22-279) is fused to the N-terminus of the Fc region of human IgG1. Mouse T cell immunoglobulin and mucin domain-containing protein 4, also known as T cell membrane protein 4, TIMD4 and TIM4 is a single-pass type I membrane protein which belongs to the immunoglobulin...
| Schlagworte: | Tim4, TIM-4, Timd4, TIMD-4, SMUCKLER, T-cell membrane protein 4, Spleen, mucin-containing, knockout of lymphotoxin... |
| Anwendung: | Bioassays |
| Exprimiert in: | Hamster cells |
| Ursprungsart: | mouse |
523,00 €
IL-6 (mouse):Fc (mouse) (rec.) (non-lytic) MultiPack
Artikelnummer: CHI-MF-12006-C050
The extracellular domain of mouse IL-6 (aa 25-211) is fused at the C-terminus to the Fc portion of a mutant mouse IgG2a. Lyophilized from 0.2µm-filtered solution in PBS. Shows the biological function of the IL-6 moiety and exerts a prolonged circulating half-life caused by the modified Fc domain. Interleukin 6...
| Schlagworte: | Il6, IL-6, Interleukin-6, Interleukin HP-1, B-cell hybridoma growth factor |
| Anwendung: | Bioassays |
| Exprimiert in: | Hamster cells |
| Ursprungsart: | mouse |
303,00 €
IL-21 (mouse):Fc (mouse) (rec.) (non-lytic)
Artikelnummer: CHI-MF-12021-C050
The extracellular domain of mouse IL-21 (aa 18-139) is fused at the C-terminus to the Fc portion of a mutant mouse IgG2a. Lyophilized from 0.2µm-filtered solution in PBS. Shows the biological function of the IL-21 moiety and exerts a prolonged circulating half-life caused by the modified Fc domain. Interleukin-21...
| Schlagworte: | Interleukin-21 |
| Anwendung: | Bioassays |
| Exprimiert in: | Hamster cells |
| Ursprungsart: | mouse |
468,00 €
CD152 [CTLA-4] (mouse):Fc (mouse) (rec.) (non-lytic)
Artikelnummer: CHI-MF-120A4-C100
The extracellular domain of mouse CD152 [CTLA-4] (aa 1-160) is fused to the N-terminus of the Fc region of a mutant mouse IgG2a. Lyophilized from 0.2µm-filtered solution in PBS. Blocks the binding of mouse CD80 (B7-1) and CD86 (B7-2) to their receptors (by binding CD80 and CD86 with high affinity) and thereby...
| Schlagworte: | Ctla4, CD152, Cd152, CTLA-4, Cytotoxic T-lymphocyte protein 4, Cytotoxic T-lymphocyte-associated antigen 4 |
| Anwendung: | Bioassays |
| Exprimiert in: | Mouse cells |
| Ursprungsart: | mouse |
ab 132,00 €
CD275 [B7-H2] (mouse):Fc (mouse) (rec.) (non-lytic)
Artikelnummer: CHI-MF-120B7H2-C100
The extracellular domain of mouse CD275 [B7-H2] (aa 48-279) is fused to the N-terminus of the Fc region of a mutant mouse IgG2a. Mouse CD275 (B7-H2) is a member of the growing B7 family of immune costimulatory proteins. CD275 has been identified as the ligand for ICOS, a member of the CD28 family of co-stimulatory...
| Schlagworte: | B7h2, B7-H2, CD275, LICOS, B7RP-1, Icoslg, ICOS ligand, B7 homolog 2, B7-like protein Gl50, B7-related protein 1 |
| Anwendung: | Bioassays |
| Exprimiert in: | Hamster cells |
| Ursprungsart: | mouse |
446,00 €