Produkte von Chimerigen Laboratories
Chimerigen entwickelt und produziert einzigartige, Immunglobulin-basierte, chimäre Fusionsproteine und verwandte Forschungsprodukte mit Hilfe modernster zell- und molekularbiologischen Techniken. Diese Reagenzien werden erfolgreich in der biomedizinischen Grundlagen- und in angewandter Forschung eingesetzt.
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![CD273 [PD-L2] (human):Fc (human) (rec.) (non-lytic)](/custom/plugins/NetiThemeBiomol/Resources/Themes/Frontend/Biomol/frontend/_public/src/img/no-picture.jpg "CD273 [PD-L2] (human):Fc (human) (rec.) (non-lytic)")
CD273 [PD-L2] (human):Fc (human) (rec.) (non-lytic)
Artikelnummer: CHI-HF-220PDL2-C100
The extracellular domain of human CD273 [PD-L2] (aa 20-219) is fused at the C-terminus to the Fc portion of a mutant human IgG1. Lyophilized from 0.2µm-filtered solution in PBS. Shows the biological function of the CD273 moiety and exerts a prolonged circulating half-life caused by the modified Fc domain. T cells...
| Schlagworte: | B7DC, PD-L2, CD273, B7-DC, PDCD1LG2, PD-1 ligand 2, PDCD1 ligand 2, Butyrophilin B7-DC, Programmed death ligand 2,... |
| Anwendung: | Bioassays |
| Exprimiert in: | Hamster cells |
| Ursprungsart: | human |
429,00 €
SCF (human):Fc (human) (rec.) (non-lytic)
Artikelnummer: CHI-HF-220SCF-C050
The extracellular domain of human SCF (aa 26-187) is fused at the C-terminus to the Fc portion of a mutant human IgG1. Lyophilized from 0.2µm-filtered solution in PBS. Shows the biological function of the SCF moiety and exerts a prolonged circulating half-life caused by the modified Fc domain. Stem cell factor...
| Schlagworte: | MGF, SCF, KITLG, sKITLG, Kit ligand, c-Kit ligand, Stem cell factor, Soluble KIT ligand, Mast cell growth factor |
| Anwendung: | Bioassays |
| Exprimiert in: | Hamster cells |
| Ursprungsart: | human |
314,00 €
CD134 [OX40] (human) (rec.) (His)
Artikelnummer: CHI-HR-200CD134-C025
Human CD134 (aa 29-216) is fused at the C-terminus to a His-tag. CD134 (OX40) is a T cell activation antigen structurally belonging to a lymphocyte-specific subgroup of the nerve growth factor and tumor necrosis factor receptor superfamily, which also includes the T cell antigen CD27, B cell antigen CD40, FAS...
| Schlagworte: | CD134, TXGP1L, TNFRSF4, ACT35 antigen, OX40L receptor, Tumor necrosis factor receptor superfamily member 4, TAX... |
| Anwendung: | Bioassays |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
352,00 €
IL-6R (mouse):Fc (mouse) (rec.)
Artikelnummer: CHI-MF-11006R-C050
Interleukin 6 receptor (IL-6R, CD126) is a type I cytokine receptor, which is a protein complex consisting of an IL-6 receptor subunit (IL-6R) and interleukin 6 signal transducer glycoprotein 130 (gp130). It is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role...
| Schlagworte: | Il6st, gp130, CD130, IL-6RB, IL-6R-beta, IL-6R subunit beta, Membrane glycoprotein 130, IL-6 receptor subunit beta,... |
| Anwendung: | Bioassays |
| Exprimiert in: | Hamster cells |
| Ursprungsart: | mouse |
391,00 €
IL-21 (mouse):Fc (mouse) (rec.)
Artikelnummer: CHI-MF-11021-C050
Interleukin-21 (IL-21) is a key factor in the transition between innate and adaptive immune responses secreted by activated T cells. The IL-21 receptor (IL-21R) is expressed in lymphoid tissue, in particular by NK, B, T and dendritic cells, macrophages and endothelial cells. Recent evidence suggests that IL-21 plays...
| Schlagworte: | Il21, IL-21, Interleukin-21, Interleukin-21 |
| Anwendung: | Bioassays |
| Exprimiert in: | Human cells |
| Ursprungsart: | mouse |
| MW: | ~45 kD |
446,00 €
IL-33R [ST2] (mouse):Fc (mouse) (rec.)
Artikelnummer: CHI-MF-11033R-C050
Receptor for interleukin-33 (IL-33). Its stimulation recruits MYD88, IRAK1, IRAK4 and TRAF6 followed by phosphorylation of MAPK3/ERK1 and/or MAPK1/ERK2, MAPK14 and MAPK8 by similarity. Possibly involved in helper T cell function.
| Schlagworte: | Ly84, Il1rl1, Protein T1, Protein ST2, Lymphocyte antigen 84, Interleukin-1 receptor-like 1, Interleukin-33 Receptor,... |
| Anwendung: | Bioassays |
| Exprimiert in: | Hamster cells |
| Ursprungsart: | mouse |
391,00 €
CD152 [CTLA-4] (mouse):Fc (mouse) (rec.)
Artikelnummer: CHI-MF-110A4-C100
The extracellular domain of mouse CD152 [CTLA-4] (aa 38-160) is fused at the C-terminus to the Fc portion of mouse IgG2a. Lyophilized from 0.2µm-filtered solution in PBS. Binds both CD80 (B7-1) and CD86 (B7-2) with high affinity and inhibits CD28 signaling competitively. Kills the target cell completely. CD152...
| Schlagworte: | Ctla4, CD152, Cd152, CTLA-4, Cytotoxic T-lymphocyte protein 4, Cytotoxic T-lymphocyte-associated antigen 4 |
| Anwendung: | Bioassays |
| Exprimiert in: | Mouse cells |
| Ursprungsart: | mouse |
ab 132,00 €
CD275 [B7-H2] (mouse):Fc (mouse) (rec.)
Artikelnummer: CHI-MF-110B7H2-C100
The extracellular domain of mouse CD275 [B7-H2] (aa 48-279) is fused at the C-terminus to the Fc portion of mouse IgG2a. Lyophilized from 0.2µm-filtered solution in PBS. Mouse B7-H2, also called CD275, B7RP-1, B7h, LICOS and GL50, is a member of the growing B7 family of immune costimulatory proteins. CD275 has been...
| Schlagworte: | B7h2, B7-H2, CD275, LICOS, B7RP-1, Icoslg, ICOS ligand, B7 homolog 2, B7-like protein Gl50, B7-related protein 1 |
| Anwendung: | Bioassays |
| Exprimiert in: | Hamster cells |
| Ursprungsart: | mouse |
429,00 €
CD276 [B7-H3] (mouse):Fc (mouse) (rec.)
Artikelnummer: CHI-MF-110B7H3-C100
The extracellular domain of mouse CD276 [B7-H3] (aa 30-248) is fused to the N-terminus of the Fc region of mouse IgG2a. CD276 (B7-H3) is a member of the B7/CD28 superfamily of costimulatory molecules serving as an accessory modulator of T cell response. B7 family molecules, which are expressed on antigen-presenting...
| Schlagworte: | B7h3, B7-H3, Cd276, CD276, B7 homolog 3, CD276 antigen, Costimulatory molecule |
| Anwendung: | Bioassays |
| Exprimiert in: | Hamster cells |
| Ursprungsart: | mouse |
429,00 €
B7-H4 (mouse):Fc (mouse) (rec.)
Artikelnummer: CHI-MF-110B7H4-C100
The extracellular domain of mouse B7-H4 (aa 29-258) is fused to the N-terminus of the Fc region of mouse IgG2a. B7-H4 is a B7 family member that negatively regulates T cell immunity by inhibiting T cell proliferation, cytokine production and cell cycle progression. In vitro, B7-H4 inhibits CD4+ and CD8+ T cell...
| Schlagworte: | B7h4, Vtcn1, Protein B7S1, T cell costimulatory molecule B7x, Immune costimulatory protein B7-H4, V-set domain containing... |
| Anwendung: | Inhibitor of anti-CD3-induced proliferation of stimulated mouse T cells |
| Exprimiert in: | Hamster cells |
| Ursprungsart: | mouse |
429,00 €
BTNL2 (mouse):Fc (mouse) (rec.)
Artikelnummer: CHI-MF-110BTNL2-C100
Butyrophilin-like 2 (BTNL2) is a butyrophilin family member with homology to the B7 costimulatory molecules, polymorphisms of which have been recently associated through genetic analysis, to sporadic inclusion body myositis and sarcoidosis. BTNL2 mRNA is highly expressed in lymphoid tissues as well as in intestine....
| Schlagworte: | Gm315, Btnl2, Butyrophilin-like protein 2, Butyrophilin-like Protein 2 |
| Anwendung: | Bioassays |
| Exprimiert in: | Hamster cells |
| Ursprungsart: | mouse |
468,00 €
CCL20 (mouse):Fc (mouse) (rec.)
Artikelnummer: CHI-MF-110CCL20-C050
Macrophage Inflammatory Protein-3 (MIP3A) or Chemokine (C-C motif) ligand 20 (CCL20) or liver activation regulated chemokine (LARC) or is a small cytokine belonging to the CC chemokine family that attracts immature dendritic cells and memory T lymphocytes, both expressing CCR6. Depending on the cell type, this...
| Schlagworte: | Larc, Ccl20, MIP-3-alpha, CC chemokine ST38, CC chemokine LARC, C-C motif chemokine 20, Beta-chemokine exodus-1,... |
| Anwendung: | Bioassays |
| Exprimiert in: | Human cells |
| Ursprungsart: | mouse |
| MW: | ~38 kD |
369,00 €