Produkte von Chemodex
Chemodex Ltd. aus der Schweiz (2001 in St. Gallen gegründet) sind Experten in der Synthese von fluoreszierenden Substanzen, die von Farbstoffen wie Coumarin, Fluorescein, Rhodamin oder Pyren abgeleitet sind. Die Substanzen können als Sonden, Farbstoffe, Marker, NIR-Labels, pH-Sensoren, Ionen-Indikatoren, Chelate und in anderen Applikationen (bspw. in der analytischen Biochemie, Immunoassays und Mikroskopie) eingesetzt werden. Zielgruppen der Produkte sind Naturwissenschaftler*innen in Universitäten und Forschungseinrichtungen sowie in der Biotechnologie- und Pharma-Industrie.
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Sildenafil citrate
Artikelnummer: CDX-S0078-M050
White to off-white powder. Soluble in DMSO (20mg/ml). Potent cGMP-specific phosphodiesterase inhibitor that is highly selective for PDE5. It inhibits PDE5 activity in isolated rabbit platelets with an IC50 value of 3.6nM (3nM in human corpus cavernosum) compared to inhibition of PDE1 and PDE3 activities (IC50s =...
| Schlagworte: | 5-[2-Ethoxy-5-(4-methylpiperazin-1-yl)sulfonylphenyl]-1-methyl-3-propyl-4H-pyrazolo[5,4-e]pyrimidin-7-one citrate salt,... |
| Anwendung: | PDE5 inhibitor |
| CAS | 171599-83-0 |
| MW: | 666,7 D |
ab 153,00 €
5(6)-CFDA N-succinimidyl ester
Artikelnummer: CDX-C0037-M050
White or slightly yellow powder. Soluble in DMSO or DMF. 5(6)-Carboxyfluorescein diacetate N-succinimidyl ester is a useful fluorescent tracer that can passivley diffuse into cells and covalently label intracellular proteins, resulting in long-term cell labeling. The reagent itself is colorless and nonfluorescent...
| Schlagworte: | 5(6)-Carboxyfluorescein diacetate N-succinimidyl ester |
| Anwendung: | Fluorogenic intracellular protein labeling |
| CAS | 150347-59-4 |
| MW: | 557,46 D |
ab 199,00 €
5-Dodecanoylaminofluorescein
Artikelnummer: CDX-D0162-M050
Yellow to beige powder. Soluble in DMF or DMSO. Lipophilic fluorescent cell staining probe contains a C12 alkyl chain that will bind to membranes with the fluorophore at the aqueous interface and the alkyl tail protruding into the lipid interior. Useful to label plasma mebranes. Binds strongly to amphiphilic block...
| Schlagworte: | AFC12 |
| Anwendung: | Lipophilic fluorescent cell staining probe, Plasma membrane labeling |
| CAS | 107827-77-0 |
| MW: | 529,62 D |
ab 138,00 €
Furanone C-30
Artikelnummer: CDX-B0220-M010
Crystalline. Soluble in ether. Quorum sensing inhibitor. Interfers with the actions of acyl-HSL molecules and inhibits gene expression regulated by quorum-sensing systems.
| Schlagworte: | (Z)-4-Bromo-5-(brommethylen)-2(5H)-furanone |
| Anwendung: | Quorum sensing inhibitor |
| CAS | 247167-54-0 |
| MW: | 253,88 D |
ab 114,00 €
7-(Diethylamino)coumarin-3-carbohydrazide
Artikelnummer: CDX-D0035-M050
Solid. Soluble in methanol, DMF, acetonitrile or chloroform. Derivatizing agent for carboxylic acid detection. Has also been used for fluorescence detection of monoterpene alcohols.
| Anwendung: | Derivatizing agent, Carboxylic acid detection |
| CAS | 100343-98-4 |
| MW: | 275,3 D |
ab 290,00 €
JC-1
Artikelnummer: CDX-T0046-M010
Solid. Soluble in methanol, DMSO. A dual-emission potential-sensitive probe that can be used to measure mitochondrial membrane potential. JC-1 is a green-fluorescent monomer at low membrane potential. At higher potentials, JC-1 forms red-fluorescent "J-aggregates," which exhibit broad excitation and very narrow...
| Schlagworte: | JC-1 jodide |
| Anwendung: | Potential-sensitive probe |
| CAS | 3520-43-2 |
| MW: | 652,23 D |
ab 453,00 €
5-CFDA
Artikelnummer: CDX-C0039-M025
Yellow solid. Soluble in DMSO. Carboxyfluorescein diacetate (CFDA), which was originally used to measure intracellular pH but was soon adapted for use as a cell viability indicator. Upon hydrolysis by intracellular nonspecific esterases, CFDA forms carboxyfluorescein. As compared with fluorescein, carboxyfluorescein...
| Schlagworte: | 5-Carboxyfluorescein diacetate |
| Anwendung: | Cell viability indicator |
| CAS | 79955-27-4 |
| MW: | 460,39 D |
ab 80,00 €
2,4-Difluororesorcinol
Artikelnummer: CDX-D0329-G001
Off-white solid. Soluble in dimethylformamide. Fluorinated building block for dye synthesis. Key precusor for preparing Pacific Blue dyes. Precursor that can be used for preparing fluorescent dyes such as fluorescein, coumarin and resorufin analogs.
| Schlagworte: | 2,4-Difluoro-1,3-dihydroxy benzene, 2,4-Difluorobenzene-1,3-diol |
| Anwendung: | Building block, Dye synthesis |
| CAS | 195136-71-1 |
| MW: | 146,09 D |
ab 153,00 €
7-Methoxy-4-(trifluoromethyl)coumarin
Artikelnummer: CDX-M0015-M050
White powder. Soluble in ethanol, methanol, DMSO or DMF. Fluorescent substrate for oxidoreductases, especially for Cytochrome P450.
| Schlagworte: | Methyl 4-(trifluoromethyl)umbelliferyl ether |
| Anwendung: | Fluorescent oxidoreductase substrate |
| CAS | 575-04-2 |
| MW: | 244,17 D |
ab 110,00 €
Resazurin sodium salt
Artikelnummer: CDX-R0051-G005
Solid. Soluble in water. Fluorescent reagent.
| Schlagworte: | 7-Hydroxy-3H-phenoxazin-3-one-10-oxide sodium salt |
| Anwendung: | Fluorescent reagent |
| CAS | 62758-13-8 |
| MW: | 251,17 D |
ab 80,00 €
Merocyanin 540
Artikelnummer: CDX-M0033-M100
Divided solid. Soluble in water, DMSO, ethanol or methanol. Sensitive probe for membrane potential. Selective staining of immature hemopoietic cells in flow cytometry.
| Anwendung: | FC, Sensitive membrane potential probe |
| CAS | 62796-23-0 |
| MW: | 569,67 D |
ab 108,00 €
(±)-Verapamil hydrochloride
Artikelnummer: CDX-V0007-M100
White powder. Soluble in methanol (50 mg/ml), ethanol or water. Verapamil hydrochloride is an alpha-adrenergic receptor (alpha-AR) antagonist and calcium channel protein inhibitor that blocks the L-type Ca2+ channels in smooth and cardiac muscle cells. Verapamil is an antiarrhythmic agent and vasodilator known to...
| Schlagworte: | Manidon |
| Anwendung: | Calcium channel L type blocker |
| CAS | 152-11-4 |
| MW: | 491,06 D |
ab 37,00 €