Produkte von Chemodex
Chemodex Ltd. aus der Schweiz (2001 in St. Gallen gegründet) sind Experten in der Synthese von fluoreszierenden Substanzen, die von Farbstoffen wie Coumarin, Fluorescein, Rhodamin oder Pyren abgeleitet sind. Die Substanzen können als Sonden, Farbstoffe, Marker, NIR-Labels, pH-Sensoren, Ionen-Indikatoren, Chelate und in anderen Applikationen (bspw. in der analytischen Biochemie, Immunoassays und Mikroskopie) eingesetzt werden. Zielgruppen der Produkte sind Naturwissenschaftler*innen in Universitäten und Forschungseinrichtungen sowie in der Biotechnologie- und Pharma-Industrie.
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Amlodipine besylate
Artikelnummer: CDX-A0569-M010
Amlodipine is a long acting calcium channel antagonist that selectively inhibits calcium ion influx across cell membranes. It acts at the voltage gated calcium channel of the CaV1 or L-type class. It targets L-type calcium channels in muscle cells and N-type calcium channels in the central nervous system which are...
| Schlagworte: | 2-[(2-Aminoethoxy)-methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-3,5- pyridinedicarboxylic acid 3-ethyl 5-methyl ester... |
| Anwendung: | Long acting calcium channel antagonist, Selective calcium ion influx inhibitor across cell membrane |
| CAS | 111470-99-6 |
| MW: | 567.05 D |
ab 105,00 €
Biotin-X-NHS
Artikelnummer: CDX-B0139-M025
Biotin-X-NHS is an amino-reactive biotinylation reagent with a long spacer arm. The 6-aminocaproic acid spacer arm provides distance between the biotin and the target ligand which helps alleviate steric hindrance. Biotin-X-NHS is used to biotinylate antibodies, proteins, peptides, or amino acids by reacting with...
| Schlagworte: | NHS-LC-Biotin, Biotinamidohexanoic acid N-hydroxysuccinimide ester, (+)-Biotinamidocaproate N-hydroxysuccinimidyl ester,... |
| Anwendung: | Amino-reactive biotinylation reagent (long spacer) |
| CAS | 72040-63-2 |
| MW: | 454.54 D |
ab 46,00 €
Biotin-X
Artikelnummer: CDX-B0143-M100
Biotin-X is an amino-reactive biotinylation reagent with a long spacer arm. The 6-aminocaproic acid spacer arm provides distance between the biotin and the target ligand which helps alleviate steric hindrance. Biotin-X can be used to biotinylate antibodies, proteins, peptides, or amino acids by reacting with primary...
| Schlagworte: | N-(+)-Biotinyl-6-aminohexanoic acid, Biotin caproic acid, (+)-Biotin-epsilon-aminocaproic acid,... |
| Anwendung: | Amino-reactive biotinylation reagent (long spacer) |
| CAS | 72040-64-3 |
| MW: | 357.47 D |
ab 122,00 €
(+)-Biotin-PFP-ester
Artikelnummer: CDX-B0308-M100
Amine-reactive biotinylation agent.
| Schlagworte: | Biotin-PFP ester, D-Biotin pentafluorophenyl ester, EZ-Link PFP-Biotin |
| Anwendung: | Amine-reactive biotinylation agent |
| CAS | 120550-35-8 |
| MW: | 410.36 D |
ab 183,00 €
Clomiphene citrate
Artikelnummer: CDX-C0696-G001
Clomiphene is a nonsteroidal triphenylethylene derivative. It acts as a selective estrogen receptor modulator (SERM), that impairs the activation of estrogen receptors (ERs) by 17beta-estradiol, similar to tamoxifen and raloxifene. It potently binds both ERalpha and ERbeta (Ki = 0.9 and 1.2nM, respectively)....
| Schlagworte: | Clomifene, Omifin, NSC 35770, 2-(4-[2-Chloro-1,2-diphenylethenyl]phenoxy)-N,N-diethylethanamine, Clomiphene citrate salt |
| Anwendung: | Estrogen receptor agonist/antagonist |
| CAS | 50-41-9 |
| MW: | 598.08 D |
ab 37,00 €
Domperidone
Artikelnummer: CDX-D0809-M100
Domperidone is a peripheral dopamine D2-like receptor antagonist that does not readily cross the blood-brain barrier. It demonstrates a potent affinity for the rat D2 receptor and is also reported to inhibit the rat D3 receptor. The antidopaminergic effects are cross-realted to its gastroprokinetic and antiemetic...
| Schlagworte: | R33812, 4-(5-Chloro-2-oxo-1-benzimidazolinyl)-1-[3-(2-oxobenzimidazolinyl)propyl]piperidine, Motilium, NSC 299589 |
| Anwendung: | Peripheral dopamine D2-like receptor antagonist |
| CAS | 57808-66-9 |
| MW: | 425.91 D |
ab 114,00 €
COVID-19 Forschung
Fluoxetine hydrochloride
Artikelnummer: CDX-F0141-M010
Fluoxetine is a cell-permeable selective serotonin reuptake inhibitor (SSRI), with preference for the serotonin transporter (Kd=0.81nM) over the norepinephrine transporter (Kd=240nM) and the dopamine transporter (Kd=3600nM). This drug works at presynaptic terminals where it prevents the reuptake of serotonin,...
| Schlagworte: | (±)-N-Methyl-gamma-[4-(trifluoromethyl)phenoxy]benzenepropanamine hydrochloride, LY-110,140 hydrochloride, Prozac |
| Anwendung: | Selective serotonin reuptake inhibitor (SSRI) |
| CAS | 56296-78-7 |
ab 31,00 €
Glimepiride
Artikelnummer: CDX-G0208-G001
Glimepiride is a long-acting sulfonylurea antidiabetic agent inhibiting ATP-sensitive potassium (KATP) channels in pancreatic beta-cells, which leads to the release of insulin. In addition, Glimepiride increases the activity of intracellular insulin receptors. Studies conducted on adipocytes and skeletal muscle...
| Schlagworte: | trans-3-Ethyl-2,5-dihydro-4-methyl-N-[2-[4-[[[[trans-4-methylcyclohexyl)amino]carbonyl]amino]sulfonyl]phenyl]ethyl]-2-oxo-... |
| Anwendung: | Antidiabetic, Hypoglycemic, Sulfonylurea receptor agonist |
| CAS | 93479-97-1 |
| MW: | 490.62 D |
ab 54,00 €
Levocetirizine dihydrochloride
Artikelnummer: CDX-L0121-M010
Levocetirizine hydrochloride is the (R)-enantiomer of the histamine H1 receptor antagonist and antihistamine agent cetirizine. It binds to the H1 receptor with higher affinity than cetirizine and is 25,000-100,000-fold selective for H1 receptors over muscarinic M1-M5 receptors. Intranasal administration...
| Schlagworte: | (R)-Cetirizine dihydrochloride, (-)-Cetirizine dihydrochloride,... |
| Anwendung: | Histamine H1 receptor antagonist |
| CAS | 130018-87-0 |
| MW: | 461.81 D |
ab 55,00 €
Olanzapine
Artikelnummer: CDX-O0143-G001
Olanzapine is a 5-HT2 serotonin and D1/D2 dopamine receptor antagonist, that binds to dopamine D1, D2, and D4 receptors (Ki=31, 11, and 27 nM, respectively) as well as the serotonin (5-HT) receptor subtypes 5-HT2A, 5-HT2C and 5-HT3 (Ki=4, 11, and 57 nM, respectively). It also binds to M1 muscarinic acetylcholine,...
| Schlagworte: | 2-Methyl-4-(4-methyl-1-piperazinyl)- 10H-thieno[2,3-b][1,5]benzodiazepine, LY-170053 |
| Anwendung: | 5-HT2 serotonin/D1/D2 dopamine receptor antagonist |
| CAS | 132539-06-1 |
| MW: | 312.43 D |
ab 108,00 €
Pristane
Artikelnummer: CDX-P0161-L025
Pristane is a hydrocarbon oil adjuvant that is used as an inflammation-inducing agent to induce tumorigenesis in mice and to induce autoimmune diseases in rodents. As a rheumatoid arthritis-inducing agent, it is used in research to understand the pathogenesis of rheumatoid arthritis and lupus. It works as an...
| Schlagworte: | 2,6,10,14-Tetramethylpentadecane, Norphytan |
| Anwendung: | Hydrocarbon oil adjuvant, Inflammation-inducing agent |
| CAS | 1921-70-6 |
| MW: | 268.52 D |
ab 276,00 €
Pyridoxal 5'-phosphate monohydrate
Artikelnummer: CDX-P0461-G005
The enzyme cofactor Pyridoxal-5'-phosphate monohydrate is a vitamin B6 metabolite that can modify lysyl and valyl residues in proteins. It acts as a coenzyme in transamination reactions by forming a Schiff-base linkage with lysine groups on aminotransferase. Also serves as a coenzyme in some decarboxylation and...
| Schlagworte: | P5P, PLP, Codecarboxylase, 3-Hydroxy-2-methyl-5-([phosphonooxy]methyl)-4-pyridinecarboxaldehyde, Pyridoxal 5-phosphate,... |
| Anwendung: | Vitamin B6 metabolite |
| CAS | 41468-25-1 |
| MW: | 265.16 D |
ab 77,00 €