Produkte von Chemodex
Chemodex Ltd. aus der Schweiz (2001 in St. Gallen gegründet) sind Experten in der Synthese von fluoreszierenden Substanzen, die von Farbstoffen wie Coumarin, Fluorescein, Rhodamin oder Pyren abgeleitet sind. Die Substanzen können als Sonden, Farbstoffe, Marker, NIR-Labels, pH-Sensoren, Ionen-Indikatoren, Chelate und in anderen Applikationen (bspw. in der analytischen Biochemie, Immunoassays und Mikroskopie) eingesetzt werden. Zielgruppen der Produkte sind Naturwissenschaftler*innen in Universitäten und Forschungseinrichtungen sowie in der Biotechnologie- und Pharma-Industrie.
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Nintedanib (free base)
Artikelnummer: CDX-N0321-M025
Nintedanib is an orally bioavailable and potent triple angiokinase inhibitor with potential antiangiogenic and antineoplastic activities. It targets the proangiogenic pathways mediated by the the receptor tyrosine kinases VEGFR1/2/3 (IC50=13-34nM), FGFR1/2/3 (IC50=37-108nM) and PDGFRalpha/beta (IC50=59-65nM), which...
| Schlagworte: | BIBF-1120, BIBF1120 |
| Anwendung: | Antiangiogenic / antineoplastic tyrosine kinase inhibitor |
| CAS | 656247-17-5 |
| MW: | 539.6 D |
ab 68,00 €
Neratinib
Artikelnummer: CDX-N0326-M050
Neratinib is a cell-permable, irreversible, selective inhibitor of the HER2 kinase (IC50=59nM) and EGFR (IC50=92nM) by preventing phosphorylation of these proteins by their respective kinases. It also potently inhibits several mutants of HER2 and shows 10-fold or greater selectivity over a wide variety of other...
| Schlagworte: | HKI-272 |
| Anwendung: | Antineoplastic, Cell-permable, irreversible, selective HER2 / EGFR inhibitor |
| CAS | 698387-09-6 |
| MW: | 557 D |
ab 122,00 €
N-(3-Oxononanoyl)-L-homoserine lactone
Artikelnummer: CDX-O0153-M010
N-(3-Oxononanoyl)-L-homoserine lactone is a small diffusible signaling molecule and is a member of N-acyl-homoserine lactone family. N-acylhomoserine lactones (AHL) are involved in quorum sensing, controlling gene expression and cellular metabolism. The diverse applications of this kind of molecule include...
| Schlagworte: | 3-Oxo-C9-HSL, 3OC9-HSL, 3-Oxo-N-[(3S)-tetrahydro-2-oxo-3-furanyl]nonanamide |
| Anwendung: | Bacterial signaling molecule , Quorum sensing |
| CAS | 441350-70-5 |
| MW: | 255.31 D |
ab 77,00 €
Prosulfocarb sulfoxide
Artikelnummer: CDX-P0507-M005
Metabolite of the herbicide Prosulfocarb. Can be used as a reference compound. Product References: Appearance: Colourless liquid. Solubility: Soluble in chloroform or acetonitrile. Identity: Determined by 1H-NMR. InChi Key: SRUUWJFBIOVZLU-UHFFFAOYSA-N Smiles: [O-][S+](C(N(CCC)CCC)=O)CC1=CC=CC=C1
| Schlagworte: | 1-Benzylsulfinyl-N,N-dipropylformamide, Prosulfocarb metabolite |
| Anwendung: | Herbicide prosulfocarb metabolite, Reference compound. |
| CAS | 51954-81-5 |
| MW: | 267.39 D |
ab 99,00 €
D-Iditol
Artikelnummer: CDX-D0854-M100
D-Iditol is a chiral molecule for chemical synthesis. It has been shown to inhibit glucosidase I, but not glucosidase II when used at a concentration of 1 mM. References: (1) S. Muniruzzaman, et al., Glycobiology 6, 795 (1996) , (2) H. Sasahara, et al., J. Biosci. Bioeng. 87, 548 (1999) Appearance: Colorless high...
| Schlagworte: | (2R,3S,4S,5R)-Hexane-1,2,3,4,5,6-hexaol, NSC 227898 |
| Anwendung: | Glucosidase I inhibitor, Chiral chemical synthesis |
| CAS | 25878-23-3 |
| MW: | 182.17 D |
ab 99,00 €
o-Dianisidine
Artikelnummer: CDX-D1023-G010
o-Dianisidine is a peroxidase substrate and used as a redox indicator dye. Redox indicators are colorimetric reagents which provide a characteristic color change at a specific electrode potential. o-Dianisidine has been has been used for neutrophil myeloperoxidase activity (MPO) assay or measurment of...
| Schlagworte: | 3,3´-Dimethoxybenzidine, Fast Blue B, Dianisidine, Acetamine diazo black RD, CI Disperse black 6, Cibacete diazo navy blue... |
| Anwendung: | Peroxidase substrate |
| CAS | 119-90-4 |
| MW: | 244.29 D |
ab 91,00 €
Rutin
Artikelnummer: CDX-R0400-M050
A polyphenolic flavonoid that acts as an antioxidant and NO scavenger. It can attenuate peroxide production in glial cells by acting as a free radical scavenger and protect renal cells from oxidative injury. Inclusion of rutin in the diet of rats significantly reduced the appearance of single-strand breaks in...
| Schlagworte: | Rutoside, Phytomelin, Sophorin, Birutan, Eldrin, Birutan Forte, Rutin trihydrate, Globularicitrin, Violaquercitrin,... |
| Anwendung: | Antioxidant, NO scavenger |
| CAS | 153-18-4 |
| MW: | 610.52 D |
122,00 €
Stains-all
Artikelnummer: CDX-S0012-G005
Stains-all is a carbocyanine dye, which stains anionic proteins, nucleic acids, anionic polysaccharides and other anionic molecules. Stains-all is metachromatic and changes its color dependent on its contact to other molecules. The detection limit for phosphoproteins is below 1ng after one hour of staining, for...
| Schlagworte: | 1-Ethyl-2-[3-(1-ethylnaphtho[1,2-d]thiazolin-2-ylidene)-2-methylpropenyl]naphtho[1,2-d]thiazolium bromide,... |
| Anwendung: | Anionic molecule staining |
| CAS | 7423-31-6 |
| MW: | 559.6 D |
ab 85,00 €
![New Indocyanine Green [IR-820]](https://www.biomol.com/media/image/ce/16/8d/CDX-N0516-G001_200x200.png "New Indocyanine Green [IR-820]")
New Indocyanine Green [IR-820]
Artikelnummer: CDX-N0516-G001
Synthetic. Appearance: Green to red-brown powder. Solubility: Soluble in DMSO or methanol. Identity: Determined by 1H-NMR. InChi Key:: RANIQVAJHXBIAY-UHFFFAOYSA-M Smiles: ClC1=C(/C=C/C2=[N+](CCCCS(=O)(O[Na])=O)C3=C(C(C=CC=C4)=C4C=C3)C2(C)C)CCC/C1=C\C=C5N(CCCCS(=O)([O-])=O)C(C=CC6=C7C=CC=C6)=C7C/5(C)C. IR-820 is a...
| Schlagworte: | IR820 Dye |
| Anwendung: | Near infrared dye (NIR) |
| CAS | 172616-80-7 |
| MW: | 849.47 D |
218,00 €
BCIP p-toluidine salt
Artikelnummer: CDX-B0024-M100
BCIP is a colorimetric substrate for alkaline phosphatase. Upon enzymatic cleavage by alkaline phosphatase, an indoxyl intermediate is released and subsequently oxidized to produce water-insoluble indigo. It can be used to detect alkaline phosphatase activity by immunohistochemistry (IHC) or Western blot (WB).
| Schlagworte: | 5-Bromo-4-chloro-3-indolyl phosphate p-toluidine salt, X-phosphate p-toluidine salt |
| Anwendung: | Colorimetric alkaline phosphatase substrate |
| CAS | 6578-06-9 |
| MW: | 433.62 D |
ab 51,00 €
![Cucurbit[6]uril hydrate](https://www.biomol.com/media/image/01/ba/f4/CDX-C0239-G001_200x200.png "Cucurbit[6]uril hydrate")
Cucurbit[6]uril hydrate
Artikelnummer: CDX-C0239-G001
Cucurbit[6]uril hydrate belongs to the Cucurbit[n]uril (CB[n], n = 5-10) family of macrocyclic compounds comprising n glycoluril units, self-assembled from an acid-catalyzed condensation reaction of glycoluril and formaldehyde. The pumpkin-shaped CB molecules have a hydrophobic cavity and two identical carbonyllaced...
| Schlagworte: | Cucurbituril |
| Anwendung: | Building block |
| CAS | 80262-44-8 |
| MW: | 996.84 D |
101,00 €
Resorufin benzyl ether
Artikelnummer: CDX-R0014-M010
Resorufin benzyl ether (7-Benzyloxyresorufin) is a fluorogenic substrate widely used for monitoring cytochrome P450 (CYP450) activities in cell extracts and solutions. It is the model substrate for 7-Benzoxyresorufin-O-dealkylase (BROD) assays. It is typically used near its apparent Km value of 30 ?M to screen the...
| Schlagworte: | Benzyloxyresorufin, 7-Benzyloxyresorufin, O7-Benzylresorufin, 7-Benzyloxy-3H-phenoxazin-3-one |
| Anwendung: | Fluorogenic cytochrome P450 (CYP450) substrate |
| CAS | 87687-02-3 |
| MW: | 303.31 D |
ab 95,00 €