Produkte von Chemodex
Chemodex Ltd. aus der Schweiz (2001 in St. Gallen gegründet) sind Experten in der Synthese von fluoreszierenden Substanzen, die von Farbstoffen wie Coumarin, Fluorescein, Rhodamin oder Pyren abgeleitet sind. Die Substanzen können als Sonden, Farbstoffe, Marker, NIR-Labels, pH-Sensoren, Ionen-Indikatoren, Chelate und in anderen Applikationen (bspw. in der analytischen Biochemie, Immunoassays und Mikroskopie) eingesetzt werden. Zielgruppen der Produkte sind Naturwissenschaftler*innen in Universitäten und Forschungseinrichtungen sowie in der Biotechnologie- und Pharma-Industrie.
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Adenine 9-beta-D-arabinofuranoside
Artikelnummer: CDX-A0279-G005
Adenine 9-beta-D-arabinofuranoside is an analog of the nucleoside adenosine that has antiviral properties. It acts as a prodrug that, once phosphorylated by cellular enzymes, acts as both substrate and inhibitor of DNA polymerase. It has been shown to be effective against H. simplex, V. zoster and Epstein-Barr...
| Schlagworte: | Adenine Arabinoside, Arabinosyladenine, 9-beta-D-Arabinofuranosyladenine, Ara-A, Vidarabine, NSC 247519, NSC 404241, Vira-A |
| Anwendung: | Antiviral |
| CAS | 5536-17-4 |
| MW: | 267.24 D |
ab 183,00 €
Ascorbic acid 6-palmitate
Artikelnummer: CDX-A0534-G025
Ascorbic acid 6-palmitate is fat-soluble form of vitamin C formed from ascorbic acid and palmitic acid and not naturally found in food sources. It is used as a source of vitamin C and as food preservative (E number E304) for stabilization fats and oils, reducing the rate of. It is also used as preservative in...
| Schlagworte: | AA6P, 6-O-Palmitoyl-L-ascorbic acid, Ascorbylpalmitic Acid, L-Ascorbic acid 6-hexadecanoate, L-Ascorbyl palmitate,... |
| Anwendung: | Antioxidant |
| CAS | 137-66-6 |
| MW: | 414.53 D |
ab 54,00 €
Curcumin
Artikelnummer: CDX-C0158-G010
Curcumin is the major yellow pigment in turmeric and curry and has antioxidant, anti-inflammatory, neuroprotective, cardioprotective, antidiabetic, antiviral, antibacterial, antifungal, chemopreventive and antitumor activities. It interferes with multiple cell signaling pathways, including cell cycle (cyclin D1 and...
| Schlagworte: | (E,E)-1,7-bis(4-Hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione, Diferuloylmethane, Diferulylmethane, Diferuloylmethane,... |
| Anwendung: | Yellow pigment, Antioxidant, Antiinflammatory, Neuroprotective |
| CAS | 458-37-7 |
| MW: | 368.38 D |
ab 61,00 €
Eicosapentaenoic acid
Artikelnummer: CDX-C0465-M100
Eicosapentaenoic acid (EPA) is one of several omega-3 fatty acids abundantly available in marine organisms. EPA has antioxidant, anti-inflammatory, cardiovascular, anticancer and antiobesity activities. EPA is a polyunsaturated fatty acid (PUFA) that acts as a precursor. When omega-3 fatty acids, like EAP is...
| Schlagworte: | EPA, cis-5,8,11,14,17-Eicosapentaenoic acid, Timnodonic acid |
| Anwendung: | omega-3 fatty acid, antioxidant, antiinflammatory, cardiovascular, anticancer, ntiobesity agent |
| CAS | 10417-94-4 |
| MW: | 302.45 D |
ab 108,00 €
Cabozantinib
Artikelnummer: CDX-C0755-M010
Cabozantinib is a potent multi-targeted receptor tyrosine kinase (RTK) inhibitor of endothelial growth factor receptor 2 (VEGFR2) (IC50=0.035nM), the hepatocyte growth factor receptor c-Met (IC50=1.3nM), AXL (IC50=7nM), fms like tyrosine kinase 3 (FLT3) (IC50=11.3nM), mast/stem cell growth factor (KIT) (IC50=4.6nM),...
| Schlagworte: | BMS-907351, XL184 |
| Anwendung: | Potent multi-targeted receptor tyrosine kinase (RTK) inhibitor |
| CAS | 849217-68-1 |
| MW: | 501.5 D |
ab 168,00 €
Doxorubicin hydrochloride
Artikelnummer: CDX-D0257-M010
Doxorubicin, a broad spectrum anthracycline antibiotic, inhibits DNA and RNA synthesis in mammalian cells and has been shown to be a very effective anti-tumor agent. Doxorubicin binds to nucleic acids by intercalating the DNA double helix and stabilizing topoisomerase II cleavage complexes, leading to DNA strand...
| Schlagworte: | DOX, Hydroxydaunorubicin, Adriamycin, NSC 123127 |
| Anwendung: | Broad spectrum anthracycline antibiotic |
| CAS | 25316-40-9 |
| MW: | 579.98 D |
ab 61,00 €
(S,S)-Ethylenediamine-N,N'-disuccinic acid
Artikelnummer: CDX-E0096-G025
Aminopolycarboxylic acid (APCA). A powerful, readily biodegradable chelant. Complexing agent, exhibiting superior biological degradation (environmentally friendly) compared to EDTA. Used in cosmetic formulations, as effective anti-oxidant and water hardness control, to reduce radical generation, as effective...
| Schlagworte: | EDDS, Ethylenediamine disuccinate, (S,S)-Ethylenediaminedisuccinic acid, N,N'-1,2-Ethanediylbis-L-aspartic acid |
| Anwendung: | Biodegradable chelant, Complexing agent |
| CAS | 20846-91-7 |
| MW: | 292.24 D |
ab 153,00 €
Ketoconazole
Artikelnummer: CDX-K0016-G001
Ketoconazole is a broad-spectrum triazole antifungal agent that has activity against C. albicans, C. krusei, C. tropicalis, C. glabrata, C. parapsilosis, C. neoformans and A. fumigatus strains (IC50s = 0.031-8 µg/ml). It inhibits the fungal cytochrome P450 (CYP) isoform CYP51, also known as lanosterol...
| Schlagworte: | (±)-cis-1-Acetyl-4-(4-[(2-[2,4-dichlorophenyl]-2-[1H-imidazol-1-ylmethyl]-1,3-dioxolan-4-yl)-methoxy]phenyl)piperazine, R... |
| Anwendung: | Antifungal, Ergosterol biosynthesis inhibitor |
| CAS | 65277-42-1 |
| MW: | 531.43 D |
ab 91,00 €
L-Ascorbic acid
Artikelnummer: CDX-L0054-G100
L-Ascorbic acid (better known as Vitamin C) is a naturally occurring electron donor and therefore serves as a reducing agent. It is synthesized from glucose in the liver of most mammalian species, excluding humans, non-human primates, or guinea pigs who must obtain it through dietary consumption. In humans,...
| Schlagworte: | L-Threoascorbic acid, Antiscorbutic factor, Vitamin C, Ascorbate, NSC 33832, NSC 218455 |
| Anwendung: | Reducing agent, Antioxidant, Ntifade reagent (live cell microscopy) |
| CAS | 50-81-7 |
| MW: | 176.12 D |
ab 79,00 €
4-Methylumbelliferyl beta-D-glucuronide dihydrate
Artikelnummer: CDX-M0076-G001
4-Methylumbelliferyl-beta-D-glucuronic acid dihydrate (MUG) is a non-fluorescent but fluorogenic beta-glucuronidase substrate. Once cleaved, MUG yields blue fluorescence seen under UV light. The substrate is commonly used for rapid sensitive identification of Escherichia coli contamination and for detecting marker...
| Schlagworte: | 4-Methylumbelliferyl-ß-D-glucopyranosiduronic acid, MUG, 4-MUG, 4-MU-glcUA, MUGlcU |
| Anwendung: | Fluorogenic, non-fluorescent beta-glucuronidase substrate |
| MW: | 352.29 D |
114,00 €
Melatonin
Artikelnummer: CDX-M0466-G005
Melatonin is an endogeneous hormone that plays a prominent role in the control of circadian rhythm that displays anti-inflammatory, anti-obesity, anti-cancer, bone-protective, cardiovascular, immunomodulatory, neuroprotective and antipoxidant (free radical scavenging) properties. Melatonin functions as a glycolytic...
| Schlagworte: | N-Acetyl-5-methoxytryptamine, NSC 56423, NSC 113928, Regulin |
| Anwendung: | Endogeneous hormone |
| CAS | 73-31-4 |
| MW: | 232.28 D |
ab 37,00 €
Nadolol
Artikelnummer: CDX-N0141-G001
Nadolol is a polar and hydrophilic, non-selective beta-adrenergic antagonist with antihypertensive and antiarrhythmic activities. It is a long-acting beta-blocker, which displays activity against beta-1 and beta-2 receptors. It has a preference for beta-1 receptors, which are predominantly located in the heart,...
| Schlagworte: | Corgard, SQ11725 |
| Anwendung: | Hydrophilic, non-selective beta-adrenergic antagonist, Antiarrhythmic, Antihypertensive, Vasodilator |
| CAS | 42200-33-9 |
| MW: | 309.4 D |
ab 68,00 €