Produkte von Chemodex
Chemodex Ltd. aus der Schweiz (2001 in St. Gallen gegründet) sind Experten in der Synthese von fluoreszierenden Substanzen, die von Farbstoffen wie Coumarin, Fluorescein, Rhodamin oder Pyren abgeleitet sind. Die Substanzen können als Sonden, Farbstoffe, Marker, NIR-Labels, pH-Sensoren, Ionen-Indikatoren, Chelate und in anderen Applikationen (bspw. in der analytischen Biochemie, Immunoassays und Mikroskopie) eingesetzt werden. Zielgruppen der Produkte sind Naturwissenschaftler*innen in Universitäten und Forschungseinrichtungen sowie in der Biotechnologie- und Pharma-Industrie.
Mehr Informationen unter: www.adipogen.com/chemodex
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Palbociclib
Artikelnummer: CDX-P0590-M005
Light-yellow or off-yellow powder, beige. Soluble in DMSO (2mg/ml). Chemical. CAS: 571190-30-2. Formula: C24H29N7O2. MW: 447.53. Palbociclib is a potent and selective inhibitor of CDK4 (IC50=11nM) and CDK6 (IC50=16nM). Displays selectivity for Cdk4/6 over a panel of 36 additional protein kinases. It exhibits...
| Schlagworte: | 6-Acetyl-8-cyclopentyl-5-methyl-2-[[5-(1-piperazinyl)-2-pyridinyl]amino]pyrido[2,3-d]pyrimidin-7(8H)-one, PD 0332991,... |
| CAS | 571190-30-2 |
| MW: | 447,53 D |
ab 68,00 €
7-Amino-4-methylcoumarin
Artikelnummer: CDX-A0021-G010
Solid. Soluble in DMSO, DMF or acetone. Widely used fluorophore, well-known for preparing fluorogenic substrates for cystine aminopeptidase and other hydrolases. Used as reference compound in enzyme assays.
| Schlagworte: | AMC, Coumarin 120 |
| Anwendung: | Reference compound, Fluorophore |
| CAS | 26093-31-2 |
| MW: | 175,18 D |
ab 99,00 €
TCEP
Artikelnummer: CDX-T0176-G002
White to off-white powder. Soluble in water (50mg/ml) or DMSO (3mg/ml). Chemical. CAS: 51805-45-9. Formula: C9H15O6P·HCl. MW: 286.60. TCEP is an odorless, selective, and water-soluble strong reducing agent that is commonly used in biochemistry and molecular biology applications. It is commonly used to rapidly reduce...
| Schlagworte: | Tris(2-carboxyethyl)phosphine hydrochloride |
| CAS | 51805-45-9 |
| MW: | 286,60 D |
ab 85,00 €
10-Acetyl-3,7-dihydroxyphenoxazine
Artikelnummer: CDX-A0022-M025
Solid. Soluble in DMSO or DMF. 10-acetyl-3,7-dihydroxyphenoxazin (Amplex Red) is a non-fluorescent, highly sensitive and stable probe for H2O2. Amplex Red is an applicable as a fluorogenic substrate for peroxidase. In the presence of horseradish peroxidase (HRP), the Amplex Red reagent reacts in a 1:1 stechiometry...
| Schlagworte: | Amplex® Red (Registered trademark of LifeTechnologies) |
| Anwendung: | H2O2 probe, Fluorogenic peroxidase substrate |
| CAS | 119171-73-2 |
| MW: | 257,24 D |
ab 290,00 €
Green CMFDA
Artikelnummer: CDX-C0103-M001
Solid. Soluble in DMSO. Fluorescent Reagent with high selectivity.
| Schlagworte: | 5-Chloromethylfluorescein diacetate |
| Anwendung: | Fluorescent Reagent |
| CAS | 136832-63-8 |
| MW: | 464,85 D |
ab 186,00 €
Diethyl azodicarboxylate
Artikelnummer: CDX-D0095-G010
Red clear liquid. Soluble in chloroform or DCM. Insoluble in water. Chemical. CAS: 1972-28-7. Formula: C6H10N2O4. MW: 174.15. Synthetic. Reagent for synthesis. Diethyl azodicarboxylate acts as a dienophile used in Diels-Alder reactions. It is used as a reagent in alpha-thiocyanation of enolizable ketones with...
| Schlagworte: | DEAD, 1,2-Ethoxycarbonyl diazene, Diethoxycarbonyldiazene, NSC 3474, NSC 679015, Unifoam AZ-AE 200 |
| CAS | 1972-28-7 |
| MW: | 174,15 D |
ab 46,00 €
BHHCT
Artikelnummer: CDX-H0041-M100
Pink powder. Soluble in DMSO. Sensitive label for time-resolved fluoroimmunoassay via the europium chelate. Ligand for TRF-complexes (with Eu3+) used for preparing Silica-Nanoparticles. This label is characterized by very large Stoke's shift, broad exitation and narrow emission bands.
| Schlagworte: | 4,4''-Bis(4,4,5,5,6,6,6-heptafluoro-1,3-dioxohexyl)-o-terphenyl-4'-sulfonyl chloride |
| Anwendung: | Labeling, time-resolved fluoroimmunoassays |
| CAS | 200862-70-0 |
| MW: | 804,93 D |
ab 80,00 €
2',7'-Dichlorofluorescein diacetate
Artikelnummer: CDX-D0064-M050
Dichlorofluorescin diacetate (H2DCFDA) is a chemically reduced analog of fluorescein, used as an indicator for reactive oxygen species (ROS) in cells. The cell permeable non-fluorescent H2DCFDA is cleaved by cellular esterases and oxidation, and converted to the highly fluorescent 2',7'-dichlorofluorescein. H2DCFDA...
| Schlagworte: | H2DCFDA, 2',7'-Dichlorodihydrofluorescein diacetate, Dichlorofluorescin DA, DCFDA, DCFH, DCFH-DA |
| Anwendung: | ROS indicator |
| CAS | 4091-99-0 |
| MW: | 487.29 D |
ab 37,00 €
![Indocyanine Green [ICG]](https://www.biomol.com/media/image/d7/d5/36/CDX-I0013-M100_200x200.png "Indocyanine Green [ICG]")
Indocyanine Green [ICG]
Artikelnummer: CDX-I0013-M100
Indocyanine green (ICG) is a cyanine dye. It is a clinically approved near infrared (NIR) fluorescent dye and used in medical diagnostics, in vitro, in vivo and animal model study. NIR fluorescence is being utilized in a wide range of research fields. ICG is a vital fluorescent dye that binds to plasma proteins and...
| Schlagworte: | Cardiogreen, Foxgreen, IC Green, Ujoviridin |
| Anwendung: | Cyanine dye, Clinically approved near infrared (NIR) fluorescent dye |
| CAS | 3599-32-4 |
| MW: | 774.98 D |
ab 138,00 €
N-(3-Oxohexanoyl)-L-homoserine lactone
Artikelnummer: CDX-O0057-M010
White solid. Soluble in chloroform. N-(3-Oxohexanoyl)-L-homoserine lactone is a small diffusible signaling molecule and is a member of N-acyl-homoserine lactone family. N-acylhomoserine lactones (AHL) are involved in quorum sensing, controlling gene expression, and cellular metabolism. The diverse applications of...
| Schlagworte: | 3-oxo-C6-HSL, N-(beta-Ketocaproyl)-L-homoserine lactone |
| Anwendung: | Quorum sensing, Gene expression control, Cellular metabolism |
| CAS | 143537-62-6 |
| MW: | 213,2 D |
ab 77,00 €
2-Fluoro-2-deoxy-D-glucose
Artikelnummer: CDX-F0076-M100
2-Fluoro-2-deoxy-D-glucose [FDG] is a glucose analog that inhibits cellular glycosylation. It is the natural isotope-form of 18F-FDG that can be taken up by cells but does not undergo metabolic glycolysis. FDG uptake is closely related to the expression of the glucose transporter (GLUT) in malignant tumours. FDG is...
| Schlagworte: | 2-Deoxy-2-fluoro-D-glucose, FDG, 2-FG, Fluorodeoxyglucose |
| Anwendung: | Glucose analog, Cellular glycolysis/glycosylation inhibitor |
| CAS | 29702-43-0 |
| MW: | 182.15 D |
ab 129,00 €
Calcein-AM
Artikelnummer: CDX-C0009-M001
Synthetic. Chemical. CAS: 148504-34-1. Formula: C46H46N2O23. MW: 994.86. Synthetic. Calcein-AM is a non-fluorescent cell permeable and hydrophobic probe that, upon entering live cells, is cleaved by intracellular esterases, releasing the membrane-impermeable, hydrophilic, and intensely bright green fluorescent...
| Schlagworte: | CAL-AM, Calcein O,O'-diacetate tetrakis(acetoxymethyl) ester, Calcein acetoxymethyl ester, NSC 689290 |
| Anwendung: | Cell permeable hydrophobic probe, cell viability assays |
| CAS | 148504-34-1 |
| MW: | 994,86 D |
183,00 €