Produkte von Chemodex
Chemodex Ltd. aus der Schweiz (2001 in St. Gallen gegründet) sind Experten in der Synthese von fluoreszierenden Substanzen, die von Farbstoffen wie Coumarin, Fluorescein, Rhodamin oder Pyren abgeleitet sind. Die Substanzen können als Sonden, Farbstoffe, Marker, NIR-Labels, pH-Sensoren, Ionen-Indikatoren, Chelate und in anderen Applikationen (bspw. in der analytischen Biochemie, Immunoassays und Mikroskopie) eingesetzt werden. Zielgruppen der Produkte sind Naturwissenschaftler*innen in Universitäten und Forschungseinrichtungen sowie in der Biotechnologie- und Pharma-Industrie.
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(+)-Bicuculline
Artikelnummer: CDX-B0239-M025
Off-white to yellow powder. Soluble in chloroform. GABAA receptor antagonist.
| Schlagworte: | (6R)-6-[(5S)-6-Methyl-5,6,7,8-tetrahydro[1,3]dioxolo[4,5-g]isoquinolin-5-yl]furo[3,4-e][1,3]benzodioxol-8(6H)-one |
| Anwendung: | GABAA receptor antagonist |
| CAS | 485-49-4 |
| MW: | 367,35 D |
ab 87,00 €
6-FAM
Artikelnummer: CDX-C0016-M200
Yellow solid. Soluble in DMSO or water (pH ? 5). The amine-reactive fluorescein derivatives are probably the most common fluorescent derivatization reagents for covalently labeling proteins. Carboxyfluorescein is better retained in cells than is fluorescein, its pKa of ~6.5 is lower than the cytosolic pH of most...
| Schlagworte: | 6-Carboxyfluorescein |
| Anwendung: | Protein labeling, Amine-reactive fluorescein derivative |
| CAS | 3301-79-9 |
| MW: | 376,32 D |
ab 108,00 €
6-CFDA
Artikelnummer: CDX-C0040-M025
White to yellow powder. Soluble in DMSO. Used to differentiate viable cells from apoptotic cells. Live cells that are not apoptotic accumulate 6-carboxyfluorescein but do not accumulate annexin. CFDA enter cells and are hydrolysed more slowly than FDA. CFDA and FDA hydrolyses obey Michaelis-Menten kinetics with Km...
| Schlagworte: | 6-Carboxyfluorescein diacetate |
| Anwendung: | Cell viability indicator |
| CAS | 3348-03-6 |
| MW: | 460,39 D |
ab 83,00 €
Carbonate ionophore VII
Artikelnummer: CDX-C0131-M050
Solid. Soluble in chloroform. Analytical/Chromatography reagent. Ion sensor compound. Ionophore potentiometric for ISE.
| Schlagworte: | N,N-Dioctyl-3alpha,12alpha-bis(4-trifluoroacetylbenzoyloxy)-5beta-cholan-24-amide |
| Anwendung: | Ion sensor |
| CAS | 222310-82-9 |
| MW: | 1016,24 D |
ab 321,00 €
DAF-2
Artikelnummer: CDX-D0084-M001
Light yellow powder. Soluble in DMSO. DAF-2 is highly sensitive reagent for NO detection and determination of nitric oxide synthase activity. DAF-2, however, remains essentially nonfluorescent until it reacts with the nitrosonium cation (produced by spontaneous oxidation of nitric oxide) to form a fluorescent...
| Schlagworte: | 4,5-Diaminofluorescein |
| Anwendung: | Nitric oxide detection |
| CAS | 205391-01-1 |
| MW: | 362,34 D |
ab 321,00 €
DTTCI
Artikelnummer: CDX-D0253-G001
Green powder. Soluble in DMSO. 3,3'-Diethylthiatricarbocyanine iodide is an IR dye.
| Schlagworte: | 3,3'-Diethylthiatricarbocyanine iodide |
| Anwendung: | IR dye |
| CAS | 3071-70-3 |
| MW: | 544,52 D |
ab 85,00 €
1,7-Dimethyluric acid
Artikelnummer: CDX-D0295-M050
White to off-white powder. Soluble in chloroform. A metabolite of caffeine with antioxidant and neuroprotective activities. Does not inhibit the differentiation of 3T3-L1 pre-adipocytes to mature adipocytes, but suppress the intracellular lipid accumulation after complete differentiation in a dose-dependent manner.
| Schlagworte: | 17U, 1,7-DMUA, 1,7-Dimethyl-1H-purine-2,6,8(3H,7H,9H)-trione |
| Anwendung: | Caffeine metabolite, Antioxidant, Neuroprotective |
| CAS | 33868-03-0 |
| MW: | 196,2 D |
ab 145,00 €
8-Hydroxy-N,N,N',N',N'',N''-hexamethyl-pyrene-1,3,6-trisu...
Artikelnummer: CDX-H0043-M010
Solid. Soluble in DMSO, DMF or alcohols. Fluorescent pH indicator for the weakly acidic pH range and enzyme substrate reference standard.
| Anwendung: | Fluorescent pH indicator |
| CAS | 127044-59-1 |
| MW: | 539,64 D |
ab 222,00 €
N-(3-Hydroxydecenoyl)-DL-homoserine lactone
Artikelnummer: CDX-H0079-M025
Solid. Soluble in DMF or acetonitrile. Quorum sensing agent.
| Schlagworte: | 3-Hydroxy-N-(tetrahydro-2-oxo-3-furanyl)-decanamide |
| Anwendung: | Quorum sensing agent |
| CAS | 929222-14-0 |
| MW: | 271,3558 D |
ab 274,00 €
IPB
Artikelnummer: CDX-I0004-M250
Pale yellow powder. Soluble in chloroform. 4-[3-(4-iodophenyl)-2-(2,4-dinitrophenyl)-2H-5-tetrazolio]-1,3-benzenedisulfonate sodium salt (IPB) have found application in clinical assays and cell proliferation assays that are based on a spectrophotometric measurement of dehydrogenase activities of cells. Disulfonated...
| Schlagworte: | 4-[3-(4-Iodophenyl)-2-(2,4-dinitrophenyl)-2H-5-tetrazolio]-1,3-benzenedisulfonate sodium salt |
| Anwendung: | Cell proliferation assays |
| CAS | 161617-45-4 |
| MW: | 696,34 D |
ab 199,00 €
4-Methylumbelliferyl acetate
Artikelnummer: CDX-M0010-G020
White powder. Soluble in DMSO or DMF. Fluorogenic substrate for esterases, broadly applied to various types of esterases, including carboxyesterases. Measurement of intracellular pH in rat proximal convoluted tubule.
| Schlagworte: | MU-Ac |
| Anwendung: | Fluorogenic esterase substrate |
| CAS | 2747-05-9 |
| MW: | 218,21 D |
ab 167,00 €
13-cis-4-Oxoretinoic acid
Artikelnummer: CDX-O0048-M001
Dark yellow powder. Soluble in acetone, chloroform, ethanol (slightly) or ether. Major active metabolites of 13-cis-retinoic acid (important drug in dermatology and treatment of neuroblastoma) with effects on gene transcription that regulate growth, differentiation and inflammation in normal and neoplastic skin...
| Schlagworte: | 4-Oxoisotretinoin, Ro 22-6595 |
| Anwendung: | Active 13-cis-retinoic acid metabolite, Reference compound |
| CAS | 71748-58-8 |
| MW: | 314,42 D |
ab 168,00 €