Produkte von Chemodex
Chemodex Ltd. aus der Schweiz (2001 in St. Gallen gegründet) sind Experten in der Synthese von fluoreszierenden Substanzen, die von Farbstoffen wie Coumarin, Fluorescein, Rhodamin oder Pyren abgeleitet sind. Die Substanzen können als Sonden, Farbstoffe, Marker, NIR-Labels, pH-Sensoren, Ionen-Indikatoren, Chelate und in anderen Applikationen (bspw. in der analytischen Biochemie, Immunoassays und Mikroskopie) eingesetzt werden. Zielgruppen der Produkte sind Naturwissenschaftler*innen in Universitäten und Forschungseinrichtungen sowie in der Biotechnologie- und Pharma-Industrie.
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Mitotane
Artikelnummer: CDX-D0724-M250
Mitotane (o,p'DDD) is an adrenocorticolytic agent primarily used in research related to adrenal gland disorders, especially adrenocortical carcinoma (ACC). Mitotane is an inhibitor of steroidogenesis and mitochondrial complex IV, also known as cytochrome c oxidase. It selectively targets adrenal cortex cells by...
| Schlagworte: | 2,4'-DDD, o,p'-DDD, 2,4'-Dichlorodiphenyl)dichloroethane, o,p'-TDE, CB 313, NSC 38721, Opeprim |
| Anwendung: | Antineoplastic, steroid biosynthesis inhibitor |
| MW: | 320.04 D |
61,00 €
3,3'-Dimethyloxacarbocyanine iodide
Artikelnummer: CDX-D0805-M050
DiOC1(3) is a fluorescent carbocyanine dye used to measure mitochondrial membrane potential or staining of plasma membranes or nucleic acid (DNA). It can be used for flow cytometry and fluorescent microscopy and for discrimination of viable cells. Also used for imaging of fixed cells. Used as a donor in TR-FRET....
| Schlagworte: | DiOC1(3), NK 86, DMOCI, 3,3'-Dimethyl-2,2'-oxacarbocyanine iodide |
| Anwendung: | Fluorescent carbocyanine dye, mitochondrial membrane potential measurement, FC, FM |
| MW: | 432.26 D |
ab 131,00 €
1,1'-Dimethyl-3,3,3',3'-tetramethyl indocarbocyanine iodide
Artikelnummer: CDX-D1024-M050
DiIC1(3) is a fluorescent carbocyanine dye used mainly for assessing membrane potential in mitochondria and plasma membranes, especially in flow cytometry and fluorescence microscopy. DiIC1(3) has short alkyl chains (methyl groups), so it diffuses more easily but is less stably anchored in membranes than...
| Schlagworte: | DiIC1(3), HICI, NK 79, 1,1',3,3,3',3'-Hexamethylindocarbocyanine iodide, Cy3 dimethyl, |
| Anwendung: | Fluorescent carbocyanine dye, mitochondria/plasma membrane membrane potential measurement, FC, FM |
| MW: | 484.43 D |
ab 131,00 €
1,1'-Dihexadecyl-3,3,3',3'-tetramethyl indocarbocyanine...
Artikelnummer: CDX-D1132-M050
DiIC16(3) is a lipophilic fluorescent carbocyanine dye used for long-term membrane labeling, cell tracking and neuronal tracing. It is weakly fluorescent in water but highly fluorescent and quite photostable when incorporated into membranes. It has an extremely high extinction coefficient and short excited-state...
| Schlagworte: | DiIC16(3) |
| Anwendung: | Lipophilic fluorescent carbocyanine dye, long-term membrane labeling, cell tracking, neuronal tracing |
| MW: | 877.76 D |
ab 182,00 €
Eleutheroside A
Artikelnummer: CDX-E0233-M010
Eleutheroside A is a natural phytosterol glycoside that exerts multiple bioactivities, like anticancer, anti-inflammatory, immunomodulatory, antibacterial and antioxidant, via modulation of cell signaling, oxidative stress, and immune responses. It modulates immune, metabolic and tumor-associated pathways....
| Schlagworte: | Daucosterol, Daucosterin, beta-Sitosterol beta-D-glucoside, beta-Sitosterol 3-O-glucoside, beta-Sitosterol... |
| Anwendung: | Bioactive natural phytosterol glycoside |
| MW: | 576.85 D |
ab 218,00 €
Eosin B
Artikelnummer: CDX-E0279-G025
Eosin B is a xanthene-class acidic dye broadly used in histology, cytology and parasitology research for its staining properties and emerging pharmacological activity. In histology, Eosin B is used primarily as a counterstain for hematoxylin in methods like the H&E stain, differentiating between cell cytoplasm and...
| Schlagworte: | 4',5'-Dibromo-2',7'-dinitrofluorescein, NSC 56650, Acid Red 91/C.I. 45400 (Sodium Salt form) |
| Anwendung: | Counterstain for hematoxylin |
| MW: | 580.09 D |
ab 87,00 €
Basic Fuchsin
Artikelnummer: CDX-F0102-G025
Basic Fuchsin is a triphenylmethane dye renowned for its intense magenta color. It is primarily used in microbiological and histological staining as it has a strong affinity for nucleic acids and cellular components, making it invaluable in the visualization of cell structures under a microscope. The mechanism of...
| Schlagworte: | C.I. Basic Violet 14, Fuchsine Basic, Basic Magenta, Rosaniline, C.I. 42510, Aizen Magenta |
| Anwendung: | Microbiological / histological staining, Gram staining |
| MW: | 337.85 D |
ab 73,00 €
7-Fluoro-2,1,3- benzoxadiazole-4-sulfonylchloride
Artikelnummer: CDX-F0577-M050
4-(Chlorosulfonyl)-7-fluoro-2,1,3-benzoxadiazole is a versatile nucleophilic intermediate or building block for the synthesis of thiol-reactive fluorogenic probes, like ADB-F, SBD-F or DBD-F. It is characterized by its unique chlorosulfonyl group that enhances electrophilic reactivity. The presence of the fluorine...
| Schlagworte: | CBD-F, 4-(Chlorosulfonyl)-7-fluoro-2,1,3-benzoxadiazole |
| Anwendung: | Building block |
| MW: | 236.61 D |
ab 145,00 €
Hydrocortisone
Artikelnummer: CDX-H0269-G001
Hydrocortisone is a glucocorticoid produced by the adrenal cortex in response to adrenocorticotropic hormone (ACTH). Hydrocortisone has three times the anti-inflammatory potency of corticosterone but much lower Na+ retention potency. It is an agonist at the mineralocorticoid receptor (MR) and the glucocorticoid...
| Schlagworte: | 11beta17alpha 21-Trihydroxypregn-4-ene-3,20-dione, Cortisol, Dihydrocostisone, NSC 10483, Kendall's compound F,... |
| Anwendung: | Glucocorticoid, glucocorticoid receptor agonist |
| MW: | 362.46 D |
ab 51,00 €
Ivabradine hydrochloride
Artikelnummer: CDX-I0177-M010
Ivabradine hydrochloride is an open channel blocker of neuronal I(h) and related cardiac I(f) channels, which are comprised of subunits of the hyperpolarisation-activated cyclic nucleotide-gated (HCN) channels. In vivo, ivabradine has antianginal activity, it reduces heart rate, incidence of ventricular tachycardia...
| Schlagworte: | 3-[3-[[[(7S)-3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]methyl]methylamino]propyl]-1,3,4,5-tetrahydro-7,8-dimethoxy-... |
| Anwendung: | Cardiotonic, HCN channel blocker |
| MW: | 505.05 D |
ab 87,00 €
D-Luciferin sodium salt
Artikelnummer: CDX-L0008-M050
D-Luciferin sodium salt is a water-soluble format of D-Luciferin. D-Luciferin is the most popular and versatile bioluminescent substrate. The firefly luciferase/luciferin bioluminescent system is found in the firefly (Photinus pyralis) and several other beetles. Firefly luciferase produces light by the ATP-dependent...
| Schlagworte: | D-(-)-Luciferin sodium salt, Firefly luciferin sodium salt, BrightGlo sodium salt,... |
| Anwendung: | Water-soluble bioluminescent substrate |
| MW: | 302.3 D |
ab 44,00 €
L-Luciferin
Artikelnummer: CDX-L0021-M050
L-Luciferin is the less active enantiomer (left-handed form) of the biologically active D-Luciferin, the most popular and versatile bioluminescent substrate. While, L-luciferin plays a biologically relevant role in the biosynthetic pathway of the firefly luciferin system, and can be enzymatically converted into the...
| Schlagworte: | (4R)-2-(6-Hydroxy-1,3-benzothiazol-2-yl)-4,5-dihydro-1,3-thiazole-4-carboxylic acid |
| Anwendung: | Less active bioluminescent substrate |
| MW: | 280.3 D |
ab 65,00 €