Produkte von Chemodex
Chemodex Ltd. aus der Schweiz (2001 in St. Gallen gegründet) sind Experten in der Synthese von fluoreszierenden Substanzen, die von Farbstoffen wie Coumarin, Fluorescein, Rhodamin oder Pyren abgeleitet sind. Die Substanzen können als Sonden, Farbstoffe, Marker, NIR-Labels, pH-Sensoren, Ionen-Indikatoren, Chelate und in anderen Applikationen (bspw. in der analytischen Biochemie, Immunoassays und Mikroskopie) eingesetzt werden. Zielgruppen der Produkte sind Naturwissenschaftler*innen in Universitäten und Forschungseinrichtungen sowie in der Biotechnologie- und Pharma-Industrie.
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Thymolphthalein
Artikelnummer: CDX-T0534-G010
Thymolphthalein is a phthalein dye used as an acid-base (pH) indicator. It changes color depending on the pH of the solution. The pH transition range is from 10.5 (deep blue). Spectral Data: lambdamax (UV-Vis): 590-598nm (0.1M NaOH). Specific Absorbance (E 1%/1cm): >750 @lambdamax. Can be used as a building block to...
| Schlagworte: | 3,3-Bis(4-hydroxy-5-isopropyl-2-methylphenyl)isobenzofuran-1(3H)-one, 5',5''-Diisopropyl-2',2''-dimethylphenolphthalein, ,... |
| Anwendung: | pH indicator |
| MW: | 430.54 D |
ab 65,00 €
L-Tyrosine
Artikelnummer: CDX-T0573-G025
L-Tyrosine is a naturally occurring non-essential amino acid that serves as a critical precursor for the synthesis of catecholamine neurotransmitters, including dopamine, norepinephrine, and epinephrine, as well as thyroid hormones and melanin. Widely used in biochemical, nutritional, and neurological research, it...
| Schlagworte: | L-4-Hydroxyphenylalanine, p-Hydroxyphenylalanine, (-)-Tyrosine, p-Tyrosine, H-L-Tyr-OH, NSC 82624, NSC 9973 |
| Anwendung: | Non-essential amino acid |
| MW: | 181.19 D |
ab 65,00 €
ThioGlo1
Artikelnummer: CDX-T0904-M010
ThioGlo1 is a thiol-reactive fluorescent probe. Upon reaction with a thiol group, a fluorescent adduct is formed that displays excitation/emission maxima of 384/513 nm, respectively. It also reacts with sulfite to form a fluorescent adduct with similar spectral characteristics, and interference from sulfite during...
| Schlagworte: | 10-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-9-methoxy-3-oxo-H-naphtho[2,1-b]pyran-2-carboxylic acid, methyl ester, ThioGlo-1 |
| Anwendung: | Thiol-reactive fluorescent probe |
| MW: | 379.32 D |
ab 85,00 €
4'-(Aminomethyl)fluorescein hydrochloride
Artikelnummer: CDX-A0075-M025
4'-(Aminomethyl)fluorescein is an excellent building block for developing fluoresceinated bioconjugates. Its amino group readily reacts with activated carboxy esters (such as NHS ester). The primary aliphatic amine of 4'-(aminomethyl)fluorescein can be reversibly coupled to aldehydes and ketones to form a Schiff...
| Schlagworte: | 4-AMF, 4'-((Aminoacetamido)methyl)fluorescein |
| Anwendung: | Building block, non-proteinogenic L-proline derivative |
| MW: | 397.81 D |
ab 210,00 €
Aldicarb sulfone
Artikelnummer: CDX-A0476-M100
Aldicarb sulfone is a metabolite of the carbamate pesticide aldicarb, fast-acting acetylcholinesterase inhibitor, and is primarily used in analytical research and environmental studies. It is commonly employed to monitor pesticide degradation and residues in soil, water and agricultural products. As a toxic compound...
| Schlagworte: | Aldicarb-sulfone, Aldoxycarb, Standak, Sulfocarb, Temik sulfone, UC 21865, UCES |
| Anwendung: | Analytical reference material, aldicarb metabolite |
| MW: | 222.26 D |
160,00 €
Apixaban
Artikelnummer: CDX-A0692-M010
Apixaban is an orally active, active site-targeting, highly potent and selective inhibitor of factor Xa (FXa), an essential component of the coagulation cascade. It functions by selectively binding to both free and clot-bound factor Xa, thereby inhibiting its activity and preventing the conversion of prothrombin to...
| Schlagworte: | 1-(4-Methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide,... |
| Anwendung: | Anticoagulant, antithrombotic, factor Xa inhibitor |
| MW: | 459.5 D |
ab 65,00 €
Bromothymol Blue
Artikelnummer: CDX-B0049-G025
Bromothymol Blue (BTB) is a sulfonephthalein-based pH indicator dye with a sharp and reversible color transition near neutrality: yellow in acidic conditions, blue in alkaline media, with a clear transition interval around pH 6.0-7.6. Bromothymol Blue is widely applied in analytical chemistry and education as a...
| Schlagworte: | 3,3'-Dibromothymolsulfophthalein, Bromothymolsulfonephthalein, NSC 7819 |
| Anwendung: | pH indicator dye |
| MW: | 624.38 D |
ab 87,00 €
7-[(Benzyloxy)methoxy]-4-(trifluoromethyl)-2H-chromen-2-one
Artikelnummer: CDX-B0733-M025
BOMFC is a fluorescent probe used to study the activity of cytochrome P450 (CYP) enzymes, specifically insecticide metabolism and pyrethroid resistance. It serves as a sensitive substrate in fluorescence-based assays to assess the inhibitory action of potential synergists and to understand the interaction of...
| Schlagworte: | BOMFC |
| Anwendung: | Fluorescent probe, cytochrome P450 substrate |
| MW: | 350.29 D |
ab 109,00 €
5(6)-Carboxy-2',7'-difluorofluorescein
Artikelnummer: CDX-C0262-M050
5(6)-Carboxy-2',7'-difluorofluorescein is a fluorinated fluorescein used as a fluorescent dye used as a building block for synthesis of fluorescent probes. It is a replacement for the widely used carboxyfluorescein and fluorescein isothiocyanate since the absorption and emission are virtually unchanged. It can be...
| Anwendung: | Building block, fluorescent dye |
| MW: | 414.32 D |
117,00 €
Cyclosporin A
Artikelnummer: CDX-C0365-M025
Cyclosporin A is a potent immunosuppressant. It forms a complex with cyclophilin D and inhibits the activity of the calcium/calmodulin-dependent protein phosphatase 2B (PP2B, calcineurin). Cyclosporin A prevents the dephosphorylation of nuclear factor of activated T cells (NFAT) transcription factor, leading to...
| Schlagworte: | Antibiotic S 7481F1, Ciclosporin A, CsA, Cyclosporine, NSC 290193, Ramihyphin A |
| Anwendung: | Immunosuppressant, calcium/calmodulin-dependent protein phosphatase 2B (PP2B, calcineurin) inhibitor |
| MW: | 1202.61 D |
ab 95,00 €
Choline chloride
Artikelnummer: CDX-C0381-G100
Choline is an essential micronutrient critical for cellular and organismal homeostasis. As a core component of phospholipids and sphingolipids, it is indispensable for membrane architecture and function. Additionally, choline is a precursor for acetylcholine, a key neurotransmitter, and betaine, a methyl donor...
| Schlagworte: | (2-Hydroxyethyl)trimethylammonium chloride, Hepacholine, Biocolina, Lipotril |
| Anwendung: | Essential micronutrient |
| MW: | 139.62 D |
51,00 €
7-Chloro-2,1,3- benzoxadiazole-4-sulfonylchloride
Artikelnummer: CDX-C0442-G001
7-Chloro-2,1,3- benzoxadiazole-4-sulfonylchloride (CBD-Cl) is used as a building block scaffold for synthesis of fluorescent dyes and other bioactive biochemical compounds.
| Schlagworte: | CBD-Cl, 4-Chloro-7-chlorosulfonyl-2,1,3-benzoxadiazole, 7-Chlorobenzo[1,2,5]oxadiazole-4-sulfonyl chloride |
| Anwendung: | Building block |
| MW: | 253.06 D |
276,00 €