Produkte von Chemodex

Chemodex

Chemodex Ltd. aus der Schweiz (2001 in St. Gallen gegründet) sind Experten in der Synthese von fluoreszierenden Substanzen, die von Farbstoffen wie Coumarin, Fluorescein, Rhodamin oder Pyren abgeleitet sind. Die Substanzen können als Sonden, Farbstoffe, Marker, NIR-Labels, pH-Sensoren, Ionen-Indikatoren, Chelate und in anderen Applikationen (bspw. in der analytischen Biochemie, Immunoassays und Mikroskopie) eingesetzt werden. Zielgruppen der Produkte sind Naturwissenschaftler*innen in Universitäten und Forschungseinrichtungen sowie in der Biotechnologie- und Pharma-Industrie.

Mehr Informationen unter: www.adipogen.com/chemodex

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1-Pyrenebutanoic acid hydrazide
1-Pyrenebutanoic acid hydrazide

Artikelnummer: CDX-P0049-G001

1-Pyrenebutanoic acid hydrazide (PBH) is a fluorescent labeling reagent commonly used in biochemistry and molecular biology. Spectral Data: lambdaex 340nm, lambdaem 375nm (MeOH). The hydrazide group reacts with carbonyl groups (like aldehydes or ketones) to form hydrazones. This makes PBH useful for labeling...
Schlagworte: PBH, 1-Pyrenebutyric hydrazide, Pyrenebutyrylhydrazine
Anwendung: Fluorescent labeling reagent, oxidized sugar/glycoprotein/carbonylated biomolecule labeling
MW: 302.37 D
ab 240,00 €
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Phenmedipham-ethyl
Phenmedipham-ethyl

Artikelnummer: CDX-P0589-M025

Phenmedipham-ethyl is an impurity of phenmedipham which is a carbanilate selective herbicide used post-emergence in beet crops after the emergence of most broad-leaved weeds and before they develop. Phenmedipham inhibits photosynthesis (photosystem II) and acts by disrupting carbon dioxide. This compound can be used...
Schlagworte: 3-Ethoxycarbonylaminophenyl 3-methylcarbanilate
Anwendung: Analytical reference material, impurity
MW: 314.34 D
117,00 €
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Pioglitazone hydrochloride
Pioglitazone hydrochloride

Artikelnummer: CDX-P0733-M010

Pioglitazone hydrochloride is a proliferator-activated receptor gamma (PPARgamma) agonist (EC50 = ~500-600nM for both human and murine PPARgamma) and thiazolidinedione (TZD) anti-diabetic. Pioglitazone is a selective agonist of the nuclear receptor peroxisome proliferator-activated receptor gamma (PPAR-gamma) and to...
Schlagworte: 5-[[4-[2-(5-Ethyl-2-pyridinyl)ethoxy]phenyl]methyl]-2,4-thiazolidinedione monohydrochloride, U 72107A
Anwendung: PPARgamma agonist
MW: 392.9 D
ab 65,00 €
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mono-Methyl phthalate
mono-Methyl phthalate

Artikelnummer: CDX-P0739-G025

Mono-methyl phthalate (MMP) is a phthalate metabolite. MMP is studied as a biodegradation product of dimethyl phthalate (DMP), a common plasticizer. It serves as an indicator of phthalate pollution and microbial degradation activity. MMP is a metabolite found in biological fluids (e.g. urine) following exposure to...
Schlagworte: MMP, Monomethyl phthalate, o-(Methoxycarbonyl)benzoic acid, Methyl 2-carboxybenzoate, 2-(1-Methoxycarbonyl)benzoic acid,...
Anwendung: Phthalate metabolite, reference compound, LC-MS, GC-MS
MW: 180.16 D
123,00 €
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Rhodamine B hydrazide
Rhodamine B hydrazide

Artikelnummer: CDX-R0178-M050

Rhodamine B hydrazide is a water-soluble fluorescent probe. Rhodamine B hydrazide can be used to label biomolecules (e.g. proteins, sugars) that have aldehyde or ketone groups. Spectral Data: lambdaex 510nm, lambdaem 578nm. It has been used for the detection of copper, peroxynitrite, nitric oxide, hydrogen peroxide,...
Schlagworte: 2-Amino-3',6'-bis(diethylamino)-spiro[1H-isoindole-1,9'-[9H]xanthen]-3(2H)-one
Anwendung: Water-soluble fluorescent probe, aldehyde / ketone group labeling
MW: 456.59 D
ab 246,00 €
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Sarcosine
Sarcosine

Artikelnummer: CDX-S0121-G025

Sarcosine (N-methylglycine) is a naturally occurring amino acid derivative that plays an important role as an intermediate in glycine and choline metabolism. It functions as a modulator of N-methyl-D-aspartate (NMDA) receptor activity a selective inhibitor of glycine transporter 1 (GlyT1), thereby enhancing synaptic...
Schlagworte: N-Methylglycine, H-NMeGly-OH, 2-(Methylamino)acetic acid
Anwendung: Naturally occurring amino acid derivative, NMDA receptor modulator, GlyT1 inhibitor
MW: 89.09 D
ab 58,00 €
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Sorafenib tosylate
Sorafenib tosylate

Artikelnummer: CDX-S0264-G005

Sorafenib tysolate is a multi-kinase inhibitor that inhibits Raf-1 and B-RAF (IC50s = 6n and 22nM, respectively), as well as the receptor tyrosine kinases VEGFR2, VEGFR3, PDGFRbeta, Flt-3, c-Kit, FGFR-1 (Flt-2) and RET, involved in neovascularization and tumor progression. It is selective for these kinases over 12...
Schlagworte: Sorafenib p-toluenesulfonate, Nexavar, ,BAY 43-9006 mono-p-tosylate, BAY 54-9085
Anwendung: Kinase inhibitor
MW: 637.03 D
ab 87,00 €
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Sunitinib malate
Sunitinib malate

Artikelnummer: CDX-S0330-G001

Sunitinib malate is a potent ATP-competitive and cell permeable multi-targeted receptor tyrosine kinase (RTK) inhibitor targeting VEGFR, PDGFR-beta and c-Kit (Ki = 2-17nM). It inhibits FLK1 (Ki=9nM), PDGFRbeta (Ki=8nM) and FLT3. It is at least 10-fold selective for FLK1 and PDGFRbeta over a variety of tyrosine...
Schlagworte: Sunitinib L-malate, SU112248,...
Anwendung: Antineoplastic, angiogenesis inhibitor, receptor tyrosine kinase inhibitor
MW: 532.56 D
305,00 €
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Sanguinarine chloride hydrate
Sanguinarine chloride hydrate

Artikelnummer: CDX-S0377-M010

Sanguinarine chloride is a quaternary ammonium benzophenanthine alkaloid found in traditional herbs such as Chelidonium, Corydalis, Sanguinarum, and Borovula. It has been proven to possess broad-spectrum biological activities, such as antitumor, anti-inflammatory, antiosteoporosis, neuroprotective, immune...
Schlagworte: Sanguinarine hydrochloride
Anwendung: Bioactive alkaloid
MW: 367.78(ah) D
ab 189,00 €
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Tetramethylrhodamine methyl ester perchlorate
Tetramethylrhodamine methyl ester perchlorate

Artikelnummer: CDX-T0012-M025

Tetramethylrhodamine methyl ester perchlorate (TMRM) is a cell-permeant, cationic fluorescent dye widely used to assess mitochondrial membrane potential and for labeling mitochondria in live-cell imaging and flow cytometry. By selectively accumulating in active mitochondria according to their membrane potential,...
Schlagworte: TMRM, TMR methyl ester
Anwendung: Cell-permeant, cationic fluorescent dye, mitochondria labeling mitochondria, live-cell imaging, FC
MW: 500.93 D
ab 204,00 €
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Tetramethylrhodamine ethyl ester perchlorate
Tetramethylrhodamine ethyl ester perchlorate

Artikelnummer: CDX-T0057-M025

Tetramethylrhodamine ethyl ester perchlorate (TMRE) is a cell-permeant, cationic fluorescent dye widely used to assess mitochondrial membrane potential and for labeling mitochondria in live-cell imaging and flow cytometry. By selectively accumulating in active mitochondria according to their membrane potential, TMRE...
Schlagworte: TMRE, TMR ethyl ester, T 669
Anwendung: Cell-permeant, cationic fluorescent dye, mitochondria labeling mitochondria, live-cell imaging, FC
MW: 514.95 D
138,00 €
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Trazodone hydrochloride
Trazodone hydrochloride

Artikelnummer: CDX-T0476-G001

Trazodone hydrochloride belongs to the class of serotonin receptor antagonists and reuptake inhibitors (SARIs). Trazodone hydrochloride has anti-depressant and neuroprotectant activity. Trazodone hydrochloride exerts antagonistic properties against alpha1- and alpha2-adrenergic receptors and histamine H1 receptors,...
Schlagworte: 2-[3-[4-(3-Chlorophenyl)-1-piperazinyl]propyl]-1,2,4-triazolo[4,3-a]pyridin-3(2H)-one hydrochloride, AF 1161, Desyrel,...
Anwendung: Serotonin antagonist and reuptake inhibitor (SARI)
MW: 408.32 D
ab 51,00 €
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