Produkte von Chemodex
Chemodex Ltd. aus der Schweiz (2001 in St. Gallen gegründet) sind Experten in der Synthese von fluoreszierenden Substanzen, die von Farbstoffen wie Coumarin, Fluorescein, Rhodamin oder Pyren abgeleitet sind. Die Substanzen können als Sonden, Farbstoffe, Marker, NIR-Labels, pH-Sensoren, Ionen-Indikatoren, Chelate und in anderen Applikationen (bspw. in der analytischen Biochemie, Immunoassays und Mikroskopie) eingesetzt werden. Zielgruppen der Produkte sind Naturwissenschaftler*innen in Universitäten und Forschungseinrichtungen sowie in der Biotechnologie- und Pharma-Industrie.
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Propiconazole solution (100µg/ml in acetonitrile)
Artikelnummer: CDX-P0414-L005
Propiconazole is a broad-spectrum triazole fungicide that inhibits ergosterol biosynthesis via the demethylation of C-14, leading to fungal cell membrane disruption. Formulations containing propiconazole have been used in the control of fungi in agriculture. It inhibits S. cerevisiae, but not rat liver, microsomal...
| Schlagworte: | PPZ, CGA 64250, CGD 92710F, Proconazole, Microban S 2140 |
| Anwendung: | Broad-spectrum triazole fungicide, ergosterol biosynthesis inhibitor |
| MW: | 342.22 D |
174,00 €
Phenylmethylsulfonyl fluoride
Artikelnummer: CDX-P0492-G001
Phenylmethylsulfonyl fluoride (PMSF) is a potent nonspecific, irreversible inhibitor of serine proteases and other enzymes, including acetylcholinesterase, palmityl coenzyme A deacylase, arylsulfatase A, chymotrypsin, and trypsin widely used in biochemical and molecular biology workflows to protect proteins from...
| Schlagworte: | alpha-Toluenesulfonyl fluoride, Benzylsulfonyl fluoride, PMSF, Phenylmethanesulfonyl fluoride, NSC 88499 |
| Anwendung: | Potent nonspecific, irreversible serine protease inhibitor |
| MW: | 174.19 D |
ab 29,00 €
Pemafibrate
Artikelnummer: CDX-P0721-M010
Pemafibrate is a peroxisome proliferator-activated receptor alpha agonist (PPARalpha EC50 = 1nM for transcriptional activity). Pemafibrate is selective for PPARalpha over PPARdelta and PPARgamma (EC50 = 2300 and 1000nM, respectively). PPARalpha is a transcription factor that is essential for regulation of lipid...
| Schlagworte: | K877, (R)-K 13675, CS-2768 |
| Anwendung: | PPARalpha agonist |
| MW: | 490.56 D |
ab 153,00 €
1-Naphthyl phosphate
Artikelnummer: CDX-P0741-G001
1-Naphthyl phosphate is a chromogenic substrate widely used in biochemical and enzymatic assays, particularly for detecting and quantifying phosphatase activity. Upon enzymatic hydrolysis by alkaline phosphatases, it releases 1-naphthol, which can be coupled with diazonium salts to form brightly colored azo dyes,...
| Schlagworte: | 1-NPP, alpha-Naphthol phosphate, alpha-Naphthyl acid phosphate, 1-Naphthyl dihydrogen phosphate, Naphthol 1-phosphate,... |
| Anwendung: | Chromogenic alkaline phosphatase substrate, IHC, ELISA |
| MW: | 224.15 D |
ab 65,00 €
Saroglitazar magnesium
Artikelnummer: CDX-S0378-M005
Saroglitazar is a potent and selective PPARalpha/gamma (peroxisome proliferator-activated receptor) agonist that exhibits lipid-lowering, antidiabetic and insulin-sensitizing effects. It also shows neuroprotective properties.
| Schlagworte: | (alphaS)-alpha-Ethoxy-4-[2-[2-methyl-5-[4-(methylthio)phenyl]-1H-pyrrol-1-yl]ethoxy]benzenepropanoic acid Magnesium,... |
| Anwendung: | PPARalpha/gamma agonist |
| MW: | 901.44 D |
ab 160,00 €
8-Amino-6-methoxyquinoline
Artikelnummer: CDX-A0655-G001
8-Amino-6-methoxyquinoline is a versatile intermediate or buliding block in medicinal chemistry and analytical research. 8-Amino-6-methoxyquinoline serves as a key intermediate in the synthesis of various pharmaceuticals, particularly antimicrobial, antibacterial, antifungal, antimalarial or neuroprotective...
| Schlagworte: | 6-Methoxy-8-aminoquinoline, Amichin, WR15081, NSC 119507, NSC 119508, NSC 13573 |
| Anwendung: | Building block |
| MW: | 174.2 D |
ab 36,00 €
Anastrozole
Artikelnummer: CDX-A0802-G001
Anastrozole is a highly potent, non-steroidal aromatase inhibitor that selectively inhibits the aromatase enzyme (CYP19A1) responsible for converting androgens to estrogens. With an IC50 in the low nanomolar range (typically ~15 nM), it effectively suppresses estrogen synthesis, making it a key compound in...
| Schlagworte: | Anastrol, ICI-D 1033, ZD 1033,... |
| Anwendung: | Non-steroidal aromatase inhibitor |
| MW: | 293.37 D |
ab 95,00 €
Antimony fluoride (SbF3)
Artikelnummer: CDX-A0988-4025
Antimony fluoride (SbF3) is an inorganic compound widely used as a fluorinating and catalyst reagent in chemical synthesis. Known for its role in the Swarts reaction, it facilitates the replacement of chlorine with fluorine in organic molecules, making it an important tool in the production of fluorocarbons,...
| Schlagworte: | Antimony(III) fluoride, Antimony trifluoride, Antimony(3+) fluoride |
| Anwendung: | Fluorinating, catalyst reagent, Swarts fluorination |
| MW: | 178.76 D |
ab 73,00 €
Bromocresol Purple
Artikelnummer: CDX-B0055-G010
Bromocresol Purple (BCP) is a pH-sensitive dye widely used as a colorimetric pH indicator and analytical reagent. It exhibits a distinct color change from yellow at pH 6.8, making it valuable in titrations, buffer preparation and biochemical assays. In clinical and laboratory settings, it is commonly used in protein...
| Schlagworte: | NSC 374134, BCP, 5,5'-Dibromo-o-cresolsulfonphthalein, |
| Anwendung: | pH indicator dye |
| MW: | 540.22 D |
ab 51,00 €
Cresol Red
Artikelnummer: CDX-C0062-G025
Cresol Red is a sulfonephthalein dye commonly used as a pH indicator and tracking dye in biochemical and molecular biology applications. It is used as an indicator with the following transition intervals: pH 1.8 (orange) to pH 2.0 (yellow), pH 7.0 (yellow) to pH 8.8 (violet) and makes it a clear visual marker for...
| Schlagworte: | o-Cresolsulfonphthalein, o-Cresol Red, 3',3''-Dimethylphenolsulfonephthalein, NSC 7224 |
| Anwendung: | pH indicator, tracking dye |
| MW: | 382.43 D |
101,00 €
N-[2-Danysylamino)ethyl]maleimide
Artikelnummer: CDX-C0069-M005
Thiol-reactive fluorescent probe. Spectral data: lambdaex=342nm, lambdaem=510nm (without thiol), lambdaex=342nm, lambdaem=530nm (with thiol).
| Schlagworte: | DNS, N-(2-Maleimidoethyl)dansylamide |
| Anwendung: | Thiol-reactive fluorescent probe |
| MW: | 373.43 D |
ab 73,00 €
Cholestyramine Resin
Artikelnummer: CDX-C1086-G025
Cholestyramine resin is a anion-exchange resin polymer. This resin is a bile acid sequestrant that interchanges chloride anions for bile acids of the small intestine lumen, leading to excretion of bile acids in the feces and reduced levels of serum bile acid. The resin induces dose-dependent reduction of low-density...
| Schlagworte: | Colestyramine, Quantalan, Cholybar, MK 135, Cholestyramine hydroxide |
| Anwendung: | Anion-exchange resin polymer, bile acid sequestrant, bile salt removal |
ab 189,00 €