Produkte von Chemodex
Chemodex Ltd. aus der Schweiz (2001 in St. Gallen gegründet) sind Experten in der Synthese von fluoreszierenden Substanzen, die von Farbstoffen wie Coumarin, Fluorescein, Rhodamin oder Pyren abgeleitet sind. Die Substanzen können als Sonden, Farbstoffe, Marker, NIR-Labels, pH-Sensoren, Ionen-Indikatoren, Chelate und in anderen Applikationen (bspw. in der analytischen Biochemie, Immunoassays und Mikroskopie) eingesetzt werden. Zielgruppen der Produkte sind Naturwissenschaftler*innen in Universitäten und Forschungseinrichtungen sowie in der Biotechnologie- und Pharma-Industrie.
Mehr Informationen unter: www.adipogen.com/chemodex
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FURA 2-AM Solution (1mM in DMSO)
Artikelnummer: CDX-F0395-M001
The fluorescent probe FURA 2/AM is a membrane-permeable derivative of the calcium chelator FURA 2. Inside cells, FURA 2/AM is rapidly hydrolyzed by cytoplasmic esterases to FURA 2, which remains within the cell. Non-invasive, intracellular calcium indicator that is UV light-excitable. Fluorescent Ca2+ indicator,...
| Schlagworte: | FURA-2 acetoxymethyl ester, FURA-2 pentakis(acetoxymethyl) ester |
| Anwendung: | Membrane-permeable FURA 2 derivative, calcium chelator |
| MW: | 1001.87 D |
240,00 €
Monobromobimane
Artikelnummer: CDX-M0061-M025
Monobromobimane (mBBr) is the most popular thiol-reactive fluorogenic probe. While bromobimane itself is essentially nonfluorescent, it alkylates thiol groups, displacing the bromine and adding the fluorescent tag to the thiol. It is cell-permeable, reacts rapidly at physiological pH with available thiol groups, and...
| Schlagworte: | Bromobimane, mBBr, Monobrombiman, Thiolyte MB, NSC 608544 |
| Anwendung: | Cell-permeable thiol-reactive fluorogenic probe |
| MW: | 271.11 D |
ab 117,00 €
TSQ
Artikelnummer: CDX-M0065-M100
TSQ (N-(6-Methoxy-8-quinolyl)-p-toluenesulfonamide) is a highly sensitive, membrane-permeable fluorescent probe widely used for the selective detection and imaging of intracellular zinc (Zn2+) ions. It is selective for Zn (II) in the presence of physiological concentrations of Ca (II) and Mg (II) ions. Upon binding...
| Schlagworte: | N-(6-Methoxy-8-quinolyl)-p-toluenesulfonamide, N-(6-Methoxy-8-quinolinyl)-4-methylbenzenesulfonamide, NSC 120213 |
| Anwendung: | Sensitive, membrane-permeable fluorescent Zn2+ probe |
| MW: | 328.39 D |
305,00 €
Marbofloxacin
Artikelnummer: CDX-M0172-M100
Marbofloxacin is a broad-spectrum fluoroquinolone antibiotic active against Gram-negative, Gram-positive and Mycoplasma spp. bacteria. It acts by inhibiting the activity of DNA gyrase and topoisomerase IV, enzymes fundamental to the replication and transcription of bacterial DNA. Thus, the inhibition of these...
| Schlagworte: | 9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-piperazino)-7-oxo-7H-pyrido[1,2,3-ij][1,2,4]benzoxadiazine-6-carboxylic acid,... |
| Anwendung: | Broad-spectrum fluoroquinolone antibiotic, antibacterial |
| MW: | 362.36 D |
109,00 €
4-Methylumbelliferyl alpha-L-fucopyranoside
Artikelnummer: CDX-M0587-M010
4-Methylumbelliferyl-alpha-L-fucopyranoside is a non-fluorescent but fluorogenic substrate for alpha-L-fucosidase (FUCA1) yielding a blue fluorescent solution. It is a fluorogenic MU substrate for detecting alpha-L-fucosidase in cell extracts and purified enzyme preparations using a fluorescence microplate reader or...
| Schlagworte: | 4-Methylumbelliferyl alpha-L-fucoside, 4-Methylumbelliferyl alpha-L-fucopyranoside, 4-'U-alpha-L-Fucopyranoside |
| Anwendung: | Fluorogenic alpha-L-fucosidase substrate |
| MW: | 322.31 D |
ab 363,00 €
Methyl coumarin-3-carboxylate
Artikelnummer: CDX-M0835-G001
Used as intermediate or building block for synthesis of fluorescent dyes and active biochemical compounds.
| Schlagworte: | Methyl 2-oxochromene-3-carboxylate, 3-(Methoxycarbonyl)coumarin, BRN0176130 |
| Anwendung: | Building block |
| MW: | 204.18 D |
ab 726,00 €
Acid Yellow 36
Artikelnummer: CDX-M0849-G010
Acid Yellow 36 is an industrial azo dye used in textiles, leather, and paper, but should not be used in foods or cosmetics due to toxicity concerns. Metanil yellow changes its color from red at 1.2 pH to yellow at pH 2.5 and has been used as a pH indicator. Metanil yellow is used as a counterstain for microscopy...
| Schlagworte: | C.I. Acid Yellow 36 monosodium salt, C.I. 13065, Acid Leather Yellow R, Metanile Yellow O, Sodium... |
| Anwendung: | Staining, pH indicator |
| MW: | 375.38 D |
117,00 €
NBD-beta-alanine
Artikelnummer: CDX-N0250-M100
NBD-beta-alanine is a conjugate of beta-alanine and the 7-nitrobenz-2-oxa-1,3-diazole (NBD) fluorophore. The NBD group is attached to the amino group of beta-alanine via an amide bond. The NBD group absorbs and emits light (typically excitation ~465 nm, emission ~535 nm), making this compound useful in...
| Schlagworte: | NBD-CO2H, NBD-COOH, N-(7-Nitro-2,1,3-benzoxadiazol-4-yl)-beta-alanine,... |
| Anwendung: | Synthesis intermediate, fluorescence-based applications |
| MW: | 252.18 D |
ab 218,00 €
4-Nitro-1,8-naphthalic anhydride
Artikelnummer: CDX-N0517-G005
4-Nitro-1,8-naphthalic anhydride is a versatile chemical intermediate and building block for the synthesis of various organic compounds. It is used synthesizing N-phenyl-amino-1,8-naphthalimide fluorescent chemosensors, especially for nitro-antibiotic detection at ppb levels, and serves as a key precursor in...
| Schlagworte: | 4-NNA, 4-Nitronaphthalic anhydride, NSC 15356 |
| Anwendung: | Building block |
| MW: | 243.17 D |
218,00 €
N-(3-Oxoheptanoyl)-L-homoserine lactone
Artikelnummer: CDX-O0138-M010
N-(3-Oxoheptanoyl)-L-homoserine lactone is a small diffusible signaling molecule and is a member of N-acyl-homoserine lactone family. N-acylhomoserine lactones (AHL) are involved in quorum sensing, controlling gene expression, and cellular metabolism. The diverse applications of this kind of molecule include...
| Schlagworte: | 3-oxo-C7-L-HSL, 3O-C7-HSL, (S)-3-Oxo-N-(2-oxotetrahydrofuran-3-yl)heptanamide |
| Anwendung: | Small diffusible signaling molecule, quorum sensing |
| MW: | 227.26 D |
ab 85,00 €
ONC212
Artikelnummer: CDX-O0207-M010
ONC212 is a potent imipridone small-molecule (and fluorinated imipridone analog of ONC201) that acts as a dual agonist of the mitochondrial protease ClpP and the orphan GPCR GPR132, provoking mitochondrial dysfunction, integrated stress response, and apoptotic cell death, particularly in acute leukemia and solid...
| Schlagworte: | TR-31, 7-Benzyl-4-(4-(trifluoromethyl)benzyl)-2,4,6,7,8,9-hexahydroimidazo[1,2-a]pyrido[3,4-e]pyrimidin-5(1H)-one, NSC-783745 |
| Anwendung: | Mitochondrial protease ClpP agonist, GPR132 agonist |
| MW: | 440.5 D |
ab 87,00 €
(S)-(+)-5-Oxo-2-tetrahydrofurancarboxylic acid
Artikelnummer: CDX-O0227-G001
(S)-(+)-5-Oxo-2-tetrahydrofurancarboxylic acid is a chiral lactone compound widely utilized in organic synthesis and medicinal chemistry. It serves as a versatile ligand for forming water-soluble silver(I) complexes, which exhibit notable antibacterial and antifungal properties. Additionally, this compound acts as a...
| Schlagworte: | S-Hothf, (S)-gamma-Carboxy-gamma-butyrolactone, (S)-5-Oxotetrahydro-2-furancarboxylic acid |
| Anwendung: | Chiral lactone, organic synthesis, medicinal chemistry |
| MW: | 130.1 D |
ab 40,00 €