Produkte von Cayman Chemical
Cayman Chemical Company ist ein Biotechunternehmen mit Sitz in Ann Arbor, Michigan, das 1980 von Kirk Maxey, M.D. gegründet wurde. Mit seinen biochemischen Produkten unterstützt Cayman Wissenschaftler*innen weltweit bei der Arbeit in den Forschungsfeldern Krebs, NO Signalling, Neurologie, Apoptose, oxidativer Stress, Endokrinologie und vielen weiteren. Cayman Chemical hat sich hierbei besonders auf die Herstellung von Assay-Kits zum Nachweis von Eicosanoiden, freien Radikalen, zyklischen Nukleotiden, Zytokinen, Hormonen und Stickstoffmonoxid spezialisiert. Neben diesen Kits bietet Cayman Chemical ein breites Angebot an Biochemikalien, darunter Eicosanoiden, NO Reagenzien sowie eine Reihe thematisch verwandter Lipide, Fettsäuren, Enzyme und Antikörper.
Mehr Informationen unter: www.caymanchem.com
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GSK467
Artikelnummer: Cay42103-1
A JARID1B inhibitor (IC50 = 0.02-0.1 µM), selective for JARID1B over KMD2, -3, -4, and -5 (IC50s = 1-10 µM). Formulation: A solid. InChI: InChI=1S/C17H13N5O2/c23-16-14-6-7-18-9-15(14)20-17(21-16)24-13-8-19-22(11-13)10-12-4-2-1-3-5-12/h1-9,11H,10H2,(H,20,21,23). InChIKey: ZTYRLXUTLYBVHH-UHFFFAOYSA-N. SMILES:...
| Schlagworte: | 2-[[1-(phenylmethyl)-1H-pyrazol-4-yl]oxy]- pyrido[3,4-d]pyrimidin-4(3H)-one |
| Anwendung: | JARID1B (KDM5B) inhibitor |
| CAS | 1628332-52-4 |
| MW: | 319.3 D |
ab 60,00 €
GSK3beta Inhibitor 1
Artikelnummer: Cay42107-10
A GSK3beta inhibitor (IC50 = 4.19 nM), decreases blood glucose levels in an OGTT in a rat model of high-fat diet and STZ-induced diabetes at 50 mg/kg. Formulation: A solid. InChI: InChI=1S/C14H10N2O/c17-14-12(9-10-5-3-4-8-15-10)11-6-1-2-7-13(11)16-14/h1-9H,(H,16,17)/b12-9-. InChIKey: YKQONSWBHGBDSB-XFXZXTDPSA-N....
| Schlagworte: | Glycogen Synthase Kinase 3beta Inhibitor I, (3Z)-1,3-dihydro-3-(2-pyridinylmethylene)-2H-indol-2-one |
| Anwendung: | GSK3beta inhibitor |
| CAS | 187325-53-7 |
| MW: | 222.2 D |
ab 223,00 €
A-425619
Artikelnummer: Cay42117-10
A TRPV1 antagonist, selective for TRPV1 over a panel of 83 receptors, enzymes, transporters, and ion channels at 10 µM, inhibits capsaicin-, NADA-, anandamide-, or acid-induced increases in intracellular calcium in HEK293 cells expressing human TRPV1 (IC50s = 5, 4, 3, and 2 nM, respectively), increases core body...
| Schlagworte: | N-5-isoquinolinyl-N'-[[4-(trifluoromethyl)phenyl]methyl]-urea |
| Anwendung: | TRPV1 antagonist |
| CAS | 581809-67-8 |
| MW: | 345.3 D |
ab 208,00 €
Voacanga africana Ethanol Extract
Artikelnummer: Cay43250-1
A natural extract, contains a crude mixture of bioactive natural products extracted from V. africana. Formulation: A solution in methanol. InChI: . InChIKey: . SMILES:
| Schlagworte: | V. africana Ethanol Extract |
| Anwendung: | Natural extract, crude mixture of bioactive natural products |
76,00 €
BSA-Stearate Saturated Fatty Acid Complex (0.34 mM)
Artikelnummer: Cay43451-5
A fatty acid substrate, can be used for efficient fatty acid delivery to cells in culture for monitoring fatty acid oxidation or similar processes in various cellular metabolic studies. Formulation: 0.34 mM Stearate:0.17 mM BSA in 150 mM sodium chloride. InChI: . InChIKey: . SMILES:
| Schlagworte: | Bovine Serum Albumin-SA, Bovine Serum Albumin-Stearate, BSA-SA |
| Anwendung: | Fatty acid substrate, efficient fatty acid delivery, cell culture |
| Exprimiert in: | Bovine |
274,00 €
D-Amino Acid Oxidase Inhibitor
Artikelnummer: Cay23894-100
An inhibitor of DAAO (IC50s = 145 and 114 nM in CHO cells expressing human and rat DAAO, respectively), selective for DAAO over a panel of 150 enzymes, receptors and ion channels (30 µM), inhibits DAAO activity in rat kidney and cerebellum in a dose- and time-dependent manner (10-200 mg/kg, i.p.), increases levels...
| Schlagworte: | DAAO inhibitor, 4H-thieno[3,2-b]pyrrole-5-carboxylic acid |
| Anwendung: | DAAO inhibitor |
| CAS | 39793-31-2 |
| MW: | 167.2 D |
ab 40,00 €
Firefly Luciferase mRNA (Cap-1, m1Psi)
Artikelnummer: Cay43677-1
An mRNA for the expression of luciferase, encapsulation in LNPs can be used for mRNA delivery and expression of luciferase. Formulation: 1 mM Sodium citrate, pH 6.4. InChI: . InChIKey: . SMILES:
| Schlagworte: | Luciferase, Luciferin 4-monooxygenase |
| Anwendung: | mRNA expression |
ab 701,00 €
HRP Development Pack
Artikelnummer: Cay502870-1
Contains a high-sensitivity and low-background substrate and stop solution for use with HRP-based ELISAs. Formulation: . InChI: . InChIKey: . SMILES:
| Anwendung: | HRP-based ELISA high-sensitivity / low-background substrates, stop solution |
ab 132,00 €
BSA-Docosahexaenoate-d5 Polyunsaturated Fatty Acid...
Artikelnummer: Cay43591-5
A fatty acid substrate, can be used for efficient fatty acid delivery to cells in culture for the purpose of monitoring fatty acid oxidation or similar processes in various cellular metabolic studies. Formulation: 1 mM Docosahexanoate-d5:0.17 mM BSA (6:1 docosahexanoate-d5:BSA) in 150 mM sodium chloride, pH 7.4....
| Schlagworte: | Bovine Serum Albumin-Docosahexaenoate-d5, BSA-DHA-d5 |
| Anwendung: | Fatty acid substrate, efficient fatty acid delivery, cell culture |
| Exprimiert in: | Bovine |
254,00 €
Mitragyna speciosa (Kratom) Methanol Extract
Artikelnummer: Cay43249-1
A natural extract, contains a crude mixture of bioactive natural products extracted from M. speciosa (Kratom)
| Schlagworte: | M. speciosa (Kratom) Methanol Extract |
| Anwendung: | Natural extract, bioactive compounds |
76,00 €
Caspase-14 (human, recombinant)
Artikelnummer: Cay43693-50
2-242 (full length). Protein function: Non-apoptotic caspase involved in epidermal differentiation. Is the predominant caspase in epidermal stratum corneum (PubMed:15556625). Seems to play a role in keratinocyte differentiation and is required for cornification. Regulates maturation of the epidermis by...
| Schlagworte: | CASP14, EC=3.4.22.- |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
456,00 €
FPPS Short Isoform (human, recombinant)
Artikelnummer: Cay43695-50
Protein function: Key enzyme in isoprenoid biosynthesis which catalyzes the formation of farnesyl diphosphate (FPP), a precursor for several classes of essential metabolites including sterols, dolichols, carotenoids, and ubiquinones. FPP also serves as substrate for protein farnesylation and geranylgeranylation....
| Schlagworte: | FPS, FPP synthase, Geranyltranstransferase, Dimethylallyltranstransferase, Farnesyl diphosphate synthase, Farnesyl... |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
456,00 €