Produkte von Cayman Chemical
Cayman Chemical Company ist ein Biotechunternehmen mit Sitz in Ann Arbor, Michigan, das 1980 von Kirk Maxey, M.D. gegründet wurde. Mit seinen biochemischen Produkten unterstützt Cayman Wissenschaftler*innen weltweit bei der Arbeit in den Forschungsfeldern Krebs, NO Signalling, Neurologie, Apoptose, oxidativer Stress, Endokrinologie und vielen weiteren. Cayman Chemical hat sich hierbei besonders auf die Herstellung von Assay-Kits zum Nachweis von Eicosanoiden, freien Radikalen, zyklischen Nukleotiden, Zytokinen, Hormonen und Stickstoffmonoxid spezialisiert. Neben diesen Kits bietet Cayman Chemical ein breites Angebot an Biochemikalien, darunter Eicosanoiden, NO Reagenzien sowie eine Reihe thematisch verwandter Lipide, Fettsäuren, Enzyme und Antikörper.
Mehr Informationen unter: www.caymanchem.com
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Erdosteine
Artikelnummer: Cay29177-500
Erdosteine is a mucolytic agent and an antioxidant. It inhibits LPS-induced IkappaB kinase (IKK) activity, NF-kappaB-mediated transcription, and production of IL-6 and IL-1beta in RAW 264.7 cells. Erdosteine (7.5 mg/kg) prevents depletion of renal catalase and glutathione peroxidase (GPX) and increases in renal...
| Schlagworte: | Erdostin, 2-[[2-oxo-2-[(tetrahydro-2-oxo-3-thienyl)amino]ethyl]thio]-acetic acid |
| Anwendung: | Mucolytic agent, antioxidant |
| CAS | 84611-23-4 |
| MW: | 249.3 D |
120,00 €
M2 Peptide
Artikelnummer: Cay40263-1
M2 peptide is an M2 tumor-associated macrophage-targeting peptide. It has been used in the generation of anticancer polymeric micelles encapsulating the STAT6 inhibitor AS1517499 (Cay-29071) for delivery to M2 tumor-associated macrophages (TAMs) in vitro and in vivo. Cayman's M2 Peptide is intended for use in...
| Schlagworte: | M2pep, TAM-targeting Peptide |
| Anwendung: | M2 TAM-targeting peptide, drug delivery |
458,00 €
SARS-CoV-2 nsp1 (recombinant)
Artikelnummer: Cay40879-100
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an enveloped positive-stranded RNA virus and the causative agent of COVID-19, a primarily respiratory illness characterized by fever, cough, and shortness of breath that can lead to life-threatening complications. The SARS-CoV-2 genome contains...
| Schlagworte: | rep, GFL, Pol, Hel, nsp1, nsp2, nsp3, nsp4, 3CLp, Mpro, nsp5, nsp6, nsp7, nsp8, nsp9, RdRp, ExoN, 1a-1b, pp1ab, nsp10,... |
| Exprimiert in: | E.coli |
| Ursprungsart: | SARS-CoV-2 |
ab 835,00 €
SARS-CoV-2 nsp4 (recombinant)
Artikelnummer: Cay40880-100
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an enveloped positive-stranded RNA virus, a member of the Betacoronavirus genus, and the causative agent of COVID-19. The SARS-CoV-2 genome contains approximately 30 kilobases and 14 open reading frames (ORFs) that encode four structural proteins:...
| Schlagworte: | rep, GFL, Pol, Hel, nsp1, nsp2, nsp3, nsp4, 3CLp, Mpro, nsp5, nsp6, nsp7, nsp8, nsp9, RdRp, ExoN, 1a-1b, pp1ab, nsp10,... |
| Exprimiert in: | E.coli |
| Ursprungsart: | SARS-CoV-2 |
ab 835,00 €
SARS-CoV-2 nsp8 (recombinant)
Artikelnummer: Cay40882-100
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an enveloped positive-stranded RNA virus and the causative agent of COVID-19, a primarily respiratory illness characterized by fever, cough, and shortness of breath that can lead to life-threatening complications. The SARS-CoV-2 genome contains...
| Schlagworte: | rep, GFL, Pol, Hel, nsp1, nsp2, nsp3, nsp4, 3CLp, Mpro, nsp5, nsp6, nsp7, nsp8, nsp9, RdRp, ExoN, 1a-1b, pp1ab, nsp10,... |
| Exprimiert in: | E.coli |
| Ursprungsart: | SARS-CoV-2 |
ab 835,00 €
Afatinib (maleate)
Artikelnummer: Cay21567-100
Afatinib is an irreversible inhibitor of epidermal growth factor receptor (EGFR) and ErbB2 (IC50s = 0.5 and 14 nM, respectively). It increases the cytotoxicity of adriamycin in a concentration-dependent manner in multidrug-resistant A549T lung cancer cells overexpressing P-glycoprotein. Afatinib (20 mg/kg) reduces...
| Schlagworte: | Afatinib dimaleate, BIBW 2992, BIBW 2992MA2,... |
| Anwendung: | EGFR / ERBB2 / ERBB4 inhibitor |
| CAS | 850140-73-7 |
| MW: | 718.1 D |
76,00 €
1-Palmitoyl-d9-2-Palmitoyl-sn-glycero-3-PC
Artikelnummer: Cay28154-100
1-Palmitoyl-d9-2-palmitoyl-sn-glycero-3-PC is intended for use as an internal standard for the quantification of 1,2-dipalmitoyl-sn-glycero-3-PC (Cay-10009473) by GC- or LC-MS. 1,2-Dipalmitoyl-sn-glycero-3-PC (DPPC) is a zwitterionic glycerophospholipid commonly used in the formation of lipid monolayers, bilayers,...
| Schlagworte: | 16:0-d9/16:0-PC, 1-Hexadecanoyl-d9-2-Hexadecanoyl-sn-glycero-3-Phosphatidylcholine,... |
| Anwendung: | GC-MS, LC-MS, internal standard, quantification |
| MW: | 743.1 D |
ab 76,00 €
1-Palmitoyl-d9-2-Palmitoyl-sn-glycero-3-PE
Artikelnummer: Cay28155-100
1-Palmitoyl-d9-2-palmitoyl-sn-glycero-3-PE is intended for use as an internal standard for the quantification of 1,2-dipalmitoyl-sn-glycero-3-PE (Cay-15092) by GC- or LC-MS. 1,2-Dipalmitoyl-sn-glycero-3-PE (1,2-DPPE) is a naturally occurring PE containing C16:0 fatty acids at the sn-1 and sn-2 positions. It belongs...
| Schlagworte: | 16:0-d9/16:0-PE, 1-Hexadecanoyl-d9-2-Hexadecanoyl-sn-glycero-3-Phosphatidylethanolamine,... |
| Anwendung: | GC-MS, LC-MS, internal standard, quantification |
| CAS | 2747990-85-6 |
| MW: | 701 D |
91,00 €
Ganoderic Acid C2
Artikelnummer: Cay30371-500
Ganoderic acid C2 is a triterpene that has been found in G. lucidum. It inhibits histamine release from isolated rat mast cells induced by concanavalin A (Cay-14951) or compound 48/80 (Cay-22173) when used at a concentration of 2 mg/ml.Formal Name: 3beta,7,15alpha-trihydroxy-11,23-dioxo-lanost-8-en-26-oic acid. CAS...
| Schlagworte: | 3beta,7,15alpha-trihydroxy-11,23-dioxo-lanost-8-en-26-oic acid |
| Anwendung: | Triterpene |
| CAS | 98296-48-1 |
| MW: | 518.7 D |
123,00 €
MPEG(30000)-NHS ester
Artikelnummer: Cay39743-100
MPEG(30000)-NHS ester is a PEGylated and esterified form of N-hydroxysuccinimide (NHS).Formal Name: 2,5-dioxopyrrolidin-1-yl 2-(2-methoxyethoxy)acetate. Synonyms: Methoxy Polyethylene Glycol-30000-NHS ester, MPEG30000-NHS ester. Molecular Formula: (C2H4O)nC7H9NO5. Purity: >90%. Formulation: (Request formulation...
| Schlagworte: | Methoxy Polyethylene Glycol-30000-NHS ester, MPEG30000-NHS ester, 2,5-dioxopyrrolidin-1-yl 2-(2-methoxyethoxy)acetate |
| Anwendung: | PEGylated, esterified NHS |
153,00 €
C6 Ceramide (d18:1/6:0) Alkyne
Artikelnummer: Cay24519-100
C6 Ceramide alkyne is an omega-alkyne derivative of C6 ceramide (Cay-62525). The terminal alkyne group can be used in click chemistry reactions to tag C6 ceramide with fluorescent or biotinylated labels for analysis of its metabolism and biological activity.Formal Name:...
| Schlagworte: | C6 Ceramide Alkyne, Cer(d18:1/6:0) Alkyne, Click Tag(TM) C6 Ceramide (d18:1/6:0) Alkyn, N-hexanoyl-D-erythro-Sphingosine... |
| Anwendung: | omega-alkyne, click chemistry |
| MW: | 393.6 D |
51,00 €
TAF 10 Peptide
Artikelnummer: Cay10228-1
TAF10 is one of many protein factors or coactivators associated with RNA polymerase II activity. One vial of this peptide may be used as a methyltransferase acceptor peptide for more than 200 reactions at 15 µM.Synonyms: TAF10 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, TBP-Associated Factor...
| Schlagworte: | TAF10 RNA Polymerase II, TAFII30, TATA Box Binding Protein (TBP)-Associated Factor, TBP-Associated Factor 10 |
| Anwendung: | Methyltransferase acceptor |
| MW: | 1267 D |
502,00 €