Produkte von Cayman Chemical
Cayman Chemical Company ist ein Biotechunternehmen mit Sitz in Ann Arbor, Michigan, das 1980 von Kirk Maxey, M.D. gegründet wurde. Mit seinen biochemischen Produkten unterstützt Cayman Wissenschaftler*innen weltweit bei der Arbeit in den Forschungsfeldern Krebs, NO Signalling, Neurologie, Apoptose, oxidativer Stress, Endokrinologie und vielen weiteren. Cayman Chemical hat sich hierbei besonders auf die Herstellung von Assay-Kits zum Nachweis von Eicosanoiden, freien Radikalen, zyklischen Nukleotiden, Zytokinen, Hormonen und Stickstoffmonoxid spezialisiert. Neben diesen Kits bietet Cayman Chemical ein breites Angebot an Biochemikalien, darunter Eicosanoiden, NO Reagenzien sowie eine Reihe thematisch verwandter Lipide, Fettsäuren, Enzyme und Antikörper.
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Citrullinated Fibrinogen (beta chain) (R44 + R47 + R60)...
Artikelnummer: Cay39128-1
Citrullinated fibrinogen (beta chain) (R44 + R47 + R60) (41-62)-biotin peptide is a biotinylated version of a tri-citrullinated form of the secreted matrix protein fibrinogen, which has been found as the citrullinated form in plasma circulating immune complexes of patients with rheumatoid arthritis. Fibrinogen is...
| Schlagworte: | FGB, Fibrinopeptide B, Fibrinogen beta chain, Fibrinogen beta chain |
| Anwendung: | Biotinylated, citrullinated fibrinogen peptide |
| MW: | 2747.9 D |
344,00 €
Anti-Citrullinated Collagen Type II (Fc Silent) (Clone...
Artikelnummer: Cay39296-200
Collagen type II is a fibril-forming heterodimeric protein present in cartilage, cartilaginous zones of tendons, and intervertebral discs that is subject to citrullination by peptidyl arginine deiminase 2 (PAD2) and PAD4. Citrullinated collagen type II and autoantibodies to citrullinated collagen type II have been...
| Schlagworte: | Anti-citrullinated-Alpha-1 type II collagen, Anti-citrullinated--Collagen alpha-1(II) chain, Anti-citrullinated-Collagen... |
| Anwendung: | ELISA, IHC |
| Wirt: | Mouse |
657,00 €
Anti-Citrullinated Collagen Type II Chimeric Rabbit...
Artikelnummer: Cay39297-200
Collagen type II is a fibril-forming heterodimeric protein present in cartilage, cartilaginous zones of tendons, and intervertebral discs that is subject to citrullination by peptidyl arginine deiminase 2 (PAD2) and PAD4. Citrullinated collagen type II and autoantibodies to citrullinated collagen type II have been...
| Schlagworte: | Anti-Alpha-1 type II collagen, Anti-Collagen alpha-1(II) chain, Anti-Collagen alpha-1(II) chain, Anti-Chondrocalcin,... |
| Anwendung: | ELISA, IHC |
| Wirt: | Rabbit/Mouse |
| Spezies-Reaktivität: | bovine, human |
657,00 €
Anti-Citrullinated Collagen Type II (Clone ACC1)
Artikelnummer: Cay39295-200
Collagen type II is a fibril-forming heterodimeric protein present in cartilage, cartilaginous zones of tendons, and intervertebral discs that is subject to citrullination by peptidyl arginine deiminase 2 (PAD2) and PAD4. Citrullinated collagen type II and autoantibodies to citrullinated collagen type II have been...
| Schlagworte: | Alpha-1 Type II Collagen, Collagen Alpha-1(II) Chain, Citrullinated Collagen Type II Monoclonal Antibody (Clone ACC1) |
| Anwendung: | ELISA, IHC |
| Wirt: | Mouse |
| Spezies-Reaktivität: | bovine, human |
610,00 €
(E/Z)-Belinostat
Artikelnummer: Cay10004279-10
(E/Z)-Belinostat is a racemic form of the class I and II histone deacetylase (HDAC) inhibitor belinostat (Cay-34084).Formal Name: N-hydroxy-3-[3-[(phenylamino)sulfonyl]phenyl]-2-propenamide. CAS Number: 414864-00-9. Synonyms: (E/Z)-PXD 101, (E/Z)-PX 105684. Molecular Formula: C15H14N2O4S. Formula Weight: 318.3....
| Schlagworte: | (E/Z)-PX 105684, (E/Z)-PXD 101, N-hydroxy-3-[3-[(phenylamino)sulfonyl]phenyl]-2-propenamide |
| Anwendung: | Belinostat (class I/II histone deacetylase (HDAC) inhibitor), racemic |
| CAS | 414864-00-9 |
| MW: | 318.3 D |
ab 54,00 €
AAA
Artikelnummer: Cay32733-500
AAA is an antagonist of G protein-coupled receptor 75 (GPR75). It increases basal GPR75 protein levels and inhibits 20-HETE-induced reductions in GPR75 protein levels in PC3 cells. AAA (5 and 10 µM) also reduces 20-HETE-induced phosphorylation of EGFR, NF-kappaB, and Akt in, and cell migration of, PC3 cells. In...
| Schlagworte: | (20-hydroxyicosa-6Z,15Z-dienoyl)aspartate, disodium salt |
| Anwendung: | GPR75 antagonist |
| MW: | 483.5 D |
197,00 €
SET7/9 Methyltransferase Inhibitor Screening Assay Kit
Artikelnummer: Cay700270-96
SET7/9 is an MT that acts on various substrates including histone 3 at lysine residue 4 (H3K4), p53, and the transcription factor TAF 10. In Cayman's SET7/9 MT Inhibitor Screening Assay the transfer of the methyl group from SAM by SET7/9 to the acceptor peptide (TAF 10) generates SAH, which is rapidly converted to...
| Schlagworte: | KMT7, SET Domain-containing Protein 7/9, SETD7/9 |
| Anwendung: | Inhibitor screening |
| Spezies-Reaktivität: | human |
1.146,00 €
SET8 Methyltransferase Inhibitor Screening Assay Kit
Artikelnummer: Cay700350-96
SET Domain-containing Protein 8 (SET8) is a methyltransferase that selectively mono-methylates histone H4 at lysine residue 20 (H4K20), an event proven to have an important role in chromatin structure and transcriptional activation. Cayman's SET8 Methyltransferase Inhibitor Screening Assay provides a convenient...
| Schlagworte: | PR-Set7, SET domain-containing (lysine methyltransferase) 8, SETD8 |
| Anwendung: | SET8 inhibitor screening |
1.146,00 €
Docetaxel Polymeric Nanoparticles
Artikelnummer: Cay39769-2
Docetaxel polymeric nanoparticles (PNPs) are nanoparticles composed of tocofersolan (TPGS, Cay-34661), poloxanlene, trehalose (Cay-20517), and TBS that encapsulate docetaxel (Cay-11637) and are 15 to 20 nm in size as determined by dynamic light scattering (DLS). PNP formulations are a lipid-based drug delivery...
| Schlagworte: | Docetaxel PNPs, Docetaxel Polymer-based Nanoparticles, DTX PNPs, RP 56976 PNPs |
| Anwendung: | Docetaxel-based PNP formulation |
1.068,00 €
1-Palmitoyl-d9-2-Palmitoyl-sn-glycero-3-PE
Artikelnummer: Cay28155-500
1-Palmitoyl-d9-2-palmitoyl-sn-glycero-3-PE is intended for use as an internal standard for the quantification of 1,2-dipalmitoyl-sn-glycero-3-PE (Cay-15092) by GC- or LC-MS. 1,2-Dipalmitoyl-sn-glycero-3-PE (1,2-DPPE) is a naturally occurring PE containing C16:0 fatty acids at the sn-1 and sn-2 positions. It belongs...
| Schlagworte: | 16:0-d9/16:0-PE, 1-Hexadecanoyl-d9-2-Hexadecanoyl-sn-glycero-3-Phosphatidylethanolamine,... |
| Anwendung: | GC-MS, LC-MS, internal standard, quantification |
| CAS | 2747990-85-6 |
| MW: | 701 D |
148,00 €
CCP-biotin Peptide (non-cyclized)
Artikelnummer: Cay35876-1
CCP-biotin peptide (non-cyclized) is a biotinylated and non-cyclized version of circular citrullinated peptide (CCP). The sequence corresponds to amino acids 447-467 of human filaggrin but contains Q447H, S449C, G459R, E460G, and S462C substitutions and is citrullinated at arginine 455. Cayman's CCP-biotin Peptide...
| Schlagworte: | Citrullinated Filaggrin (Q447H, S449C, G459R, E460G, S462C) (R455) (447-467)-biotin Peptide (non-cyclized), Cyclic... |
| Anwendung: | Citrullinated/biotinylated filaggrin peptide derivative |
345,00 €
PAMAM Dendrimer G2.0 Succinamic Acid (water solution)
Artikelnummer: Cay39119-1
PAMAM dendrimer G2.0 succinamic acid (PAMAM G2.0 succinamic acid) is a polyamidoamine (PAMAM) dendrimer with succinamic acid termini. It has 16 surface groups. PAMAM G2.0 succinamic acid is an antagonist for the pore-forming channels anthrax toxin protective antigen 63 (PA63, IC50 = 879 nM) in lipid bilayers. It is...
| Schlagworte: | PAMAM G2.0 Succinamic Acid, Polyamidoamine Dendrimer G2.0 Succinamic Acid |
| Anwendung: | Succinamic acid-terminated PAMAM dendrimer |
| MW: | 4856 D |
ab 137,00 €