Produkte von Cayman Chemical
Cayman Chemical Company ist ein Biotechunternehmen mit Sitz in Ann Arbor, Michigan, das 1980 von Kirk Maxey, M.D. gegründet wurde. Mit seinen biochemischen Produkten unterstützt Cayman Wissenschaftler*innen weltweit bei der Arbeit in den Forschungsfeldern Krebs, NO Signalling, Neurologie, Apoptose, oxidativer Stress, Endokrinologie und vielen weiteren. Cayman Chemical hat sich hierbei besonders auf die Herstellung von Assay-Kits zum Nachweis von Eicosanoiden, freien Radikalen, zyklischen Nukleotiden, Zytokinen, Hormonen und Stickstoffmonoxid spezialisiert. Neben diesen Kits bietet Cayman Chemical ein breites Angebot an Biochemikalien, darunter Eicosanoiden, NO Reagenzien sowie eine Reihe thematisch verwandter Lipide, Fettsäuren, Enzyme und Antikörper.
Mehr Informationen unter: www.caymanchem.com
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Taminadenant
Artikelnummer: Cay32799-10
An adenosine A2A receptor antagonist (Ki = 12 nM), selective for adenosine A2A receptors over adenosine A1-, A2B-, and A3 receptors (Kis = 2,500, 1,000, and 5,000 nM, respectively), increases the levels of IFN-gamma secreted by tumor-associated T cells isolated from patient-derived lung tumors at 1 µM when used in...
| Schlagworte: | NIR 178, PBF-509, 5-bromo-2,6-di-1H-pyrazol-1-yl-4-pyrimidinamine |
| Anwendung: | Adenosine A2A receptor antagonist |
| CAS | 1337962-47-6 |
| MW: | 306.1 D |
ab 60,00 €
Trifluralin
Artikelnummer: Cay35476-100
A dinitroaniline herbicide, inhibits photosynthetic electron transport, ATP synthesis, and cytochrome f reduction in isolated spinach chloroplasts, decreases cotton (G. hirsutum) plant height when applied to the soil prior to planting at 1.68 kg/ha, induces ROS production in V79 fibroblasts and genotoxicity in...
| Schlagworte: | 2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)-benzenamine |
| Anwendung: | Dinitroaniline herbicide |
| CAS | 1582-09-8 |
| MW: | 335.3 D |
ab 208,00 €
5-Hexynoic Acid
Artikelnummer: Cay35507-1
A protein labeling compound, has been used to label proteins at acylation sites in a fatty acid synthase-dependent manner, can be further conjugated to fluorescent probes or biotin via click chemistry for protein identification. Formulation: A neat liquid. InChI: InChI=1S/C6H8O2/c1-2-3-4-5-6(7)8/h1H,3-5H2,(H,7,8)....
| Schlagworte: | 5-Hexynoate, ALK-4 |
| Anwendung: | Protein labeling compound, click chemistry |
| CAS | 53293-00-8 |
| MW: | 112.1 D |
ab 40,00 €
Lisuride (maleate)
Artikelnummer: Cay36140-1
An analytical reference standard categorized as a lysergamide, does not induce the HTR in mice, indicating a lack of hallucinogenic potential, intended for research and forensic applications. Formulation: A solid. InChI:...
| Schlagworte: | Lysenyl, N'-[(8a)-9,10-didehydro-6-methylergolin-8-yl]-N,N-diethyl-urea, 2Z-butenedioate |
| Anwendung: | Analytical reference standard, lysergamide |
| CAS | 19875-60-6 |
| MW: | 454.5 D |
ab 229,00 €
NPD4928
Artikelnummer: Cay36598-1
An FSP1 inhibitor and ferroptosis enhancer, binds to FSP1 and inhibits its activity in a cell-free NADH consumption assay, synergistically enhances RSL3-induced cytotoxicity in PANC-1 prostate cancer cells at 3 µM, induces cytotoxicity in PC3, MKN74, DU145, MIA PaCa-2, and A549 cells (IC50s = 95-155 nM,...
| Schlagworte: | 2-[(9,10-dihydro-3,4,8,8-tetramethyl-2-oxo-2H,8H-benzo[1,2-b:3,4-b']dipyran-5-yl)oxy]-N-[2-(5-methoxy-1H-indol-3-yl)ethyl]... |
| Anwendung: | FSP1 inhibitor, ferroptosis enhancer |
| CAS | 956965-61-0 |
| MW: | 504.57 D |
ab 76,00 €
Poseltinib
Artikelnummer: Cay37324-1
An irreversible inhibitor of BTK (IC50 = 1.95 nM), selective for BTK over a panel of 85 additional kinases at 2 µM but does inhibit BMX, Tec, and TXK (IC50s = 0.64, 4.57, and 4.62 nM, respectively), as well as EGFR, Blk, and JAK3 (IC50s = 4.96, 13.5, and 14.6 nM, respectively), decreases the levels of CD40, CD69, or...
| Schlagworte: | HM71224, LY3337641, N-[3-[[2-[[4-(4-methyl-1-piperazinyl)phenyl]amino]furo[3,2-d]pyrimidin-4-yl]oxy]phenyl]-2-propenamide |
| Anwendung: | Irreversible BTK inhibitor |
| CAS | 1353552-97-2 |
| MW: | 470.5 D |
ab 40,00 €
Atractylon
Artikelnummer: Cay37568-10
A sesquiterpene with diverse biological activities, scavenges DPPH radicals in a cell-free assay at 0.01, 0.1, or 1 mg/ml, antagonist of dopamine D2 receptors (IC50 = 2.5 µM), inhibitor of 5-LO, (IC50 = 25.1 µM), inhibits tert-butyl hydroperoxide-induced release of ALT and LDH and increases in intracellular MDA and...
| Schlagworte: | 4,4aS,5,6,7,8,8aR,9-octahydro-3,8a-dimethyl-5-methylene-naphtho[2,3-b]furan |
| Anwendung: | Bioactive sesquiterpene |
| CAS | 6989-21-5 |
| MW: | 216.3 D |
ab 60,00 €
N-desethyl Etonitazene-d5 (citrate)
Artikelnummer: Cay37843-1
An internal standard for the quantification of N-desethyl etonitazene by GC- or LC-MS, intended for research and forensic applications. Formulation: A solid. InChI:...
| Schlagworte: | 2-(2-(4-(ethoxy-d5)benzyl)-5-nitro-1H-benzo[d]imidazol-1-yl)-N-ethylethan-1-amine, 2-hydroxypropane-1,2,3-tricarboxylic acid |
| Anwendung: | GC-MS, LC-MS, internal standard, quantification, opioid |
| MW: | 565.6 D |
ab 223,00 €
Nonafluoro-3,6-dioxaheptanoic Acid
Artikelnummer: Cay37917-100
A perfluoroalkyl ether carboxylic acid, has been found as an environmental contaminant in watersheds. Formulation: A liquid. InChI: InChI=1S/C5HF9O4/c6-2(7,1(15)16)17-3(8,9)4(10,11)18-5(12,13)14/h(H,15,16). InChIKey: PPWRLPJIHGWGFH-UHFFFAOYSA-N. SMILES: O=C(C(F)(OC(F)(C(F)(OC(F)(F)F)F)F)F)O
| Schlagworte: | NFDHA, Perfluoro-3,6-dioxaheptanoic Acid, PFO2HpA, 2,2-difluoro-2-[1,1,2,2-tetrafluoro-2-(trifluoromethoxy)ethoxy]-acetic... |
| Anwendung: | Perfluoroalkyl ether carboxylic acid (PFECA) |
| CAS | 151772-58-6 |
| MW: | 296 D |
ab 91,00 €
2,6-Dibromomescaline (hydrochloride)
Artikelnummer: Cay38616-1
An analytical reference standard categorized as a phenethylamine, intended for research and forensic applications. Formulation: A solid. InChI: InChI=1S/C11H15Br2NO3.ClH/c1-15-9-7(12)6(4-5-14)8(13)10(16-2)11(9)17-3,/h4-5,14H2,1-3H3,1H. InChIKey: UTVJYSNAXJLXSY-UHFFFAOYSA-N. SMILES: COC1=C(OC)C(Br)=C(CCN)C(Br)=C1OC.Cl
| Schlagworte: | 2,6-dibromo-3,4,5-trimethoxy-benzeneethanamine, monohydrochloride |
| Anwendung: | Analytical reference standard, phenethylamine |
| MW: | 405.51 D |
ab 149,00 €
M-110
Artikelnummer: Cay39165-1
A Pim-3 kinase inhibitor (IC50 = 0.05 µM), selective for Pim-3 over Pim-1 and Pim-2 (IC50s = 2.5 µM for both), inhibits the growth of DU145 and MIA PaCa-2 cells (IC50s = 0.9 and 3.9 µM, respectively), inhibits IL-6-induced STAT3 phosphorylation in DU145 cells at 10 µM. Formulation: A solid. InChI:...
| Schlagworte: | 2-[[3-(4-morpholinyl)propyl]amino]-4-pyridinecarboxylic acid, 2-[1-(4-chloro-2-hydroxyphenyl)propylidene]hydrazide |
| Anwendung: | Pim-3 kinase inhibitor |
| CAS | 1395048-49-3 |
| MW: | 445.9 D |
ab 40,00 €
2,3-Dimercaptopropanesulfonate (sodium salt hydrate)
Artikelnummer: Cay39521-1
A mercury chelator, reduces renal mercury levels and increases urinary mercury levels in uninephrectomized- and normal rats administered mercuric chloride, inhibits methylmercury chloride-induced increases in embryotoxicity and fetal- and maternal death and decreases in fetal bone ossification in a mouse model of...
| Schlagworte: | DMPS, 2,3-dimercapto-1-propanesulfonic acid, monosodium salt monohydrate |
| Anwendung: | Mercury chelator |
| CAS | 207233-91-8 |
| MW: | 228.3 D |
ab 101,00 €