Produkte von Cayman Chemical
Cayman Chemical Company ist ein Biotechunternehmen mit Sitz in Ann Arbor, Michigan, das 1980 von Kirk Maxey, M.D. gegründet wurde. Mit seinen biochemischen Produkten unterstützt Cayman Wissenschaftler*innen weltweit bei der Arbeit in den Forschungsfeldern Krebs, NO Signalling, Neurologie, Apoptose, oxidativer Stress, Endokrinologie und vielen weiteren. Cayman Chemical hat sich hierbei besonders auf die Herstellung von Assay-Kits zum Nachweis von Eicosanoiden, freien Radikalen, zyklischen Nukleotiden, Zytokinen, Hormonen und Stickstoffmonoxid spezialisiert. Neben diesen Kits bietet Cayman Chemical ein breites Angebot an Biochemikalien, darunter Eicosanoiden, NO Reagenzien sowie eine Reihe thematisch verwandter Lipide, Fettsäuren, Enzyme und Antikörper.
Mehr Informationen unter: www.caymanchem.com
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DSPE-PEG(2000)-Pep2
Artikelnummer: Cay43421-200
DSPE-PEG(2000)-Pep2 is a peptide-lipid conjugate that has been used for the targeted delivery of lipid nanoparticles (LNPs) in vivo. It is composed of DSPE-PEG(2000)-DCBO conjugated to Pep2 peptide (Cay-40258), a peptide ligand for the transmembrane glycoprotein CD36, also known as scavenger receptor B2, that...
| Schlagworte: | 1,2-Distearoyl Phosphatidylethanolamine-PEG(2000)-Pep2 Peptide, DSPE-PEG(2000)-RRGTIAFDNWVDTGTRVYDF, Scavenger Receptor... |
| Anwendung: | Peptide-lipid conjugate, targeted LNP in vivo delivery |
| Ursprungsart: | bovine |
305,00 €
HSA-Palmitate Saturated Fatty Acid Complex (1 mM)
Artikelnummer: Cay43472-5
HSA-Palmitate saturated fatty acid complex is composed of palmitic acid (Cay-10006627) and human serum albumin (HSA) at an approximately 6:1 molar ratio of palmitate:HSA. It can be used for efficient fatty acid delivery to cells in culture for the purpose of monitoring fatty acid oxidation or similar processes in...
| Schlagworte: | HSA-PA, Human Serum Albumin-PA, Human Serum Albumin-Palmitate |
| Anwendung: | Fatty acid substrate, efficient fatty acid delivery, cell culture |
| Exprimiert in: | Human |
| Ursprungsart: | human |
336,00 €
Sulindac
Artikelnummer: Cay10004386-1
An NSAID, a COX-2 inhibitor (IC50 = 0.79 µM), and a prodrug form of sulindac sulfide, selective for COX-2 over COX-1 (IC50 = >1,000 µM), inhibits acetic acid-induced writhing in mice and reduces carrageenan-induced paw edema in rats at 100 mg/kg, reduces tumor growth in a BxPC-3 mouse xenograft model at 60 mg/kg....
| Schlagworte: | 5-fluoro-2-methyl-1Z-[[4-(methylsulfinyl)phenyl]methylene]-1H-indene-3-acetic acid |
| Anwendung: | NSAID, COX-2 inhibitor |
| CAS | 38194-50-2 |
| MW: | 356.4 D |
ab 23,00 €
Silybin
Artikelnummer: Cay10006211-1
A flavonolignan, inhibits wild mushroom tyrosinase (IC50 = 1.7 µM), scavenges superoxide radicals (IC50 = 55.2 µM) and inhibits lipid peroxidation in vitro (IC50 = 73.92 µM). Formulation: A crystalline solid. InChI:...
| Schlagworte: | Silibinin, Silibinin A, Silybin A,... |
| Anwendung: | Hepatoprotective flavonolignan, 5-LO inhibitor |
| CAS | 22888-70-6 |
| MW: | 482.4 D |
ab 28,00 €
(±)-Ketoprofen
Artikelnummer: Cay10006661-1
A non-selective COX inhibitor (IC50s = 0.5 and 2.33 µM for human COX-1 and COX-2, respectively), reduces carrageenan-induced paw edema and increases latency to paw withdrawal in the hot plate test in rats when administered using a sustained-release implant. Formulation: A crystalline solid. InChI:...
| Schlagworte: | (R,S)-Ketoprofen, 2-(3-benzoylphenyl)Propionic Acid, 3-benzoyl-a-methyl-benzeneacetic acid |
| Anwendung: | Non-selective COX inhibitor |
| CAS | 22071-15-4 |
| MW: | 254.3 D |
ab 20,00 €
Phepropeptin A
Artikelnummer: Cay10008108-1
A cyclic peptide with proteasome inhibitory activity, inhibits isolated mouse liver proteasomes (IC50 = 21 µg/ml). Formulation: A powder. InChI:...
| Schlagworte: | Cyclic(Leu-D-Leu-Val-Leu-D-Phe-Pro),... |
| Anwendung: | Cyclic peptide, proteasome inhibitory agent |
| CAS | 396729-23-0 |
| MW: | 682.9 D |
961,00 €
Phepropeptin B
Artikelnummer: Cay10008109-1
A cyclic peptide with proteasome inhibitory activity, inhibits isolated mouse liver proteasomes (IC50 = 11 µg/ml). Formulation: A powder. InChI:...
| Schlagworte: | Cyclic(Leu-D-Phe-Pro-Phe-D-Leu-Val), cyclo(L-leucyl-D-phenylalanyl-L-prolyl-L-phenylalanyl-D-leucyl-L-valyl) |
| Anwendung: | Cyclic peptide, proteasome inhibitory agent |
| CAS | 396729-24-1 |
| MW: | 716.9 D |
961,00 €
Phepropeptin D
Artikelnummer: Cay10008111-1
A cyclic peptide with proteasome inhibitory activity, inhibits isolated mouse liver proteasomes (IC50 = 7.8 µg/ml). Formulation: A powder. InChI:...
| Schlagworte: | Cyclic(Leu-D-Phe-D-Pro-Phe-D-Leu-xi-Ile),... |
| Anwendung: | Cyclic peptide, proteasome inhibitory agent |
| CAS | 396729-26-3 |
| MW: | 730.94 D |
961,00 €
(+)-Norpropoxyphene (maleate) (CRM)
Artikelnummer: Cay19047-1
A certified reference material categorized as an opioid metabolite, a metabolite of (+)-propoxyphene, intended for research and forensic applications. Formulation: A 1 mg/ml solution in methanol. InChI:...
| Schlagworte: | D-Norpropoxyphene, (aS)-a-[(1R)-1-methyl-2-(methylamino)ethyl]-a-phenyl-benzeneethanol propanoate (ester), 2Z-butenedioate |
| Anwendung: | Certified reference material, opioid metabolite |
| CAS | 159208-83-0 |
| MW: | 441.5 D |
60,00 €
BAY 60-2770
Artikelnummer: Cay20077-1
An activator of soluble guanylate cyclase (EC50s = 592 and 573 nM for the alpha1beta1 and alpha2beta1 isoforms, respectively), increases cGMP levels in, and inhibits the aggregation of, collagen- or thrombin-activated washed isolated human platelets, effects that can be potentiated by ODQ, inhibits...
| Schlagworte: | 4-[[(4-carboxybutyl)[2-[5-fluoro-2-[[4'-(trifluoromethyl)[1,1'-biphenyl]-4-yl]methoxy]phenyl]ethyl]amino]methyl]-benzoic acid |
| Anwendung: | Soluble guanylate cyclase activator |
| CAS | 1027642-43-8 |
| MW: | 623.6 D |
ab 70,00 €
Desmethylcitalopram (hydrochloride) (CRM)
Artikelnummer: Cay23255-1
A certified reference material categorized as an antidepressant, an active metabolite of citalopram, intended for research and forensic applications. Formulation: A 1 mg/ml solution in methanol. InChI:...
| Schlagworte: | N-desmethyl Citalopram, 1-(4-fluorophenyl)-1,3-dihydro-1-[3-(methylamino)propyl]-5-isobenzofurancarbonitrile,... |
| Anwendung: | Certified reference material, antidepressant, active citalopram metabolite |
| CAS | 97743-99-2 |
| MW: | 346.83 D |
269,00 €
Apararenone
Artikelnummer: Cay30671-10
A non-steroidal mineralocorticoid receptor antagonist (Ki = 0.104 µM for the human receptor), selective for mineralocorticoid receptors over ERalpha and ERbeta and glucocorticoid, progesterone, and androgen receptors (IC50s = >100 µM for all), increases the urinary ratio of sodium to potassium in adrenalectomized...
| Schlagworte: | MT-3995, N-[4-(4-fluorophenyl)-3,4-dihydro-2,2-dimethyl-3-oxo-2H-1,4-benzoxazin-7-yl]-methanesulfonamide |
| Anwendung: | Non-steroidal mineralocorticoid receptor antagonist |
| CAS | 945966-46-1 |
| MW: | 364.4 D |
ab 90,00 €