Produkte von Cayman Chemical
Cayman Chemical Company ist ein Biotechunternehmen mit Sitz in Ann Arbor, Michigan, das 1980 von Kirk Maxey, M.D. gegründet wurde. Mit seinen biochemischen Produkten unterstützt Cayman Wissenschaftler*innen weltweit bei der Arbeit in den Forschungsfeldern Krebs, NO Signalling, Neurologie, Apoptose, oxidativer Stress, Endokrinologie und vielen weiteren. Cayman Chemical hat sich hierbei besonders auf die Herstellung von Assay-Kits zum Nachweis von Eicosanoiden, freien Radikalen, zyklischen Nukleotiden, Zytokinen, Hormonen und Stickstoffmonoxid spezialisiert. Neben diesen Kits bietet Cayman Chemical ein breites Angebot an Biochemikalien, darunter Eicosanoiden, NO Reagenzien sowie eine Reihe thematisch verwandter Lipide, Fettsäuren, Enzyme und Antikörper.
Mehr Informationen unter: www.caymanchem.com
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Phepropeptin A
Artikelnummer: Cay10008108-1
A cyclic peptide with proteasome inhibitory activity, inhibits isolated mouse liver proteasomes (IC50 = 21 µg/ml). Formulation: A powder. InChI:...
| Schlagworte: | Cyclic(Leu-D-Leu-Val-Leu-D-Phe-Pro),... |
| Anwendung: | Cyclic peptide, proteasome inhibitory agent |
| CAS | 396729-23-0 |
| MW: | 682.9 D |
961,00 €
Phepropeptin B
Artikelnummer: Cay10008109-1
A cyclic peptide with proteasome inhibitory activity, inhibits isolated mouse liver proteasomes (IC50 = 11 µg/ml). Formulation: A powder. InChI:...
| Schlagworte: | Cyclic(Leu-D-Phe-Pro-Phe-D-Leu-Val), cyclo(L-leucyl-D-phenylalanyl-L-prolyl-L-phenylalanyl-D-leucyl-L-valyl) |
| Anwendung: | Cyclic peptide, proteasome inhibitory agent |
| CAS | 396729-24-1 |
| MW: | 716.9 D |
961,00 €
Phepropeptin D
Artikelnummer: Cay10008111-1
A cyclic peptide with proteasome inhibitory activity, inhibits isolated mouse liver proteasomes (IC50 = 7.8 µg/ml). Formulation: A powder. InChI:...
| Schlagworte: | Cyclic(Leu-D-Phe-D-Pro-Phe-D-Leu-xi-Ile),... |
| Anwendung: | Cyclic peptide, proteasome inhibitory agent |
| CAS | 396729-26-3 |
| MW: | 730.94 D |
961,00 €
(+)-Norpropoxyphene (maleate) (CRM)
Artikelnummer: Cay19047-1
A certified reference material categorized as an opioid metabolite, a metabolite of (+)-propoxyphene, intended for research and forensic applications. Formulation: A 1 mg/ml solution in methanol. InChI:...
| Schlagworte: | D-Norpropoxyphene, (aS)-a-[(1R)-1-methyl-2-(methylamino)ethyl]-a-phenyl-benzeneethanol propanoate (ester), 2Z-butenedioate |
| Anwendung: | Certified reference material, opioid metabolite |
| CAS | 159208-83-0 |
| MW: | 441.5 D |
60,00 €
BAY 60-2770
Artikelnummer: Cay20077-1
An activator of soluble guanylate cyclase (EC50s = 592 and 573 nM for the alpha1beta1 and alpha2beta1 isoforms, respectively), increases cGMP levels in, and inhibits the aggregation of, collagen- or thrombin-activated washed isolated human platelets, effects that can be potentiated by ODQ, inhibits...
| Schlagworte: | 4-[[(4-carboxybutyl)[2-[5-fluoro-2-[[4'-(trifluoromethyl)[1,1'-biphenyl]-4-yl]methoxy]phenyl]ethyl]amino]methyl]-benzoic acid |
| Anwendung: | Soluble guanylate cyclase activator |
| CAS | 1027642-43-8 |
| MW: | 623.6 D |
ab 70,00 €
Desmethylcitalopram (hydrochloride) (CRM)
Artikelnummer: Cay23255-1
A certified reference material categorized as an antidepressant, an active metabolite of citalopram, intended for research and forensic applications. Formulation: A 1 mg/ml solution in methanol. InChI:...
| Schlagworte: | N-desmethyl Citalopram, 1-(4-fluorophenyl)-1,3-dihydro-1-[3-(methylamino)propyl]-5-isobenzofurancarbonitrile,... |
| Anwendung: | Certified reference material, antidepressant, active citalopram metabolite |
| CAS | 97743-99-2 |
| MW: | 346.83 D |
269,00 €
Apararenone
Artikelnummer: Cay30671-10
A non-steroidal mineralocorticoid receptor antagonist (Ki = 0.104 µM for the human receptor), selective for mineralocorticoid receptors over ERalpha and ERbeta and glucocorticoid, progesterone, and androgen receptors (IC50s = >100 µM for all), increases the urinary ratio of sodium to potassium in adrenalectomized...
| Schlagworte: | MT-3995, N-[4-(4-fluorophenyl)-3,4-dihydro-2,2-dimethyl-3-oxo-2H-1,4-benzoxazin-7-yl]-methanesulfonamide |
| Anwendung: | Non-steroidal mineralocorticoid receptor antagonist |
| CAS | 945966-46-1 |
| MW: | 364.4 D |
ab 90,00 €
Taminadenant
Artikelnummer: Cay32799-10
An adenosine A2A receptor antagonist (Ki = 12 nM), selective for adenosine A2A receptors over adenosine A1-, A2B-, and A3 receptors (Kis = 2,500, 1,000, and 5,000 nM, respectively), increases the levels of IFN-gamma secreted by tumor-associated T cells isolated from patient-derived lung tumors at 1 µM when used in...
| Schlagworte: | NIR 178, PBF-509, 5-bromo-2,6-di-1H-pyrazol-1-yl-4-pyrimidinamine |
| Anwendung: | Adenosine A2A receptor antagonist |
| CAS | 1337962-47-6 |
| MW: | 306.1 D |
ab 60,00 €
Trifluralin
Artikelnummer: Cay35476-100
A dinitroaniline herbicide, inhibits photosynthetic electron transport, ATP synthesis, and cytochrome f reduction in isolated spinach chloroplasts, decreases cotton (G. hirsutum) plant height when applied to the soil prior to planting at 1.68 kg/ha, induces ROS production in V79 fibroblasts and genotoxicity in...
| Schlagworte: | 2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)-benzenamine |
| Anwendung: | Dinitroaniline herbicide |
| CAS | 1582-09-8 |
| MW: | 335.3 D |
ab 208,00 €
5-Hexynoic Acid
Artikelnummer: Cay35507-1
A protein labeling compound, has been used to label proteins at acylation sites in a fatty acid synthase-dependent manner, can be further conjugated to fluorescent probes or biotin via click chemistry for protein identification. Formulation: A neat liquid. InChI: InChI=1S/C6H8O2/c1-2-3-4-5-6(7)8/h1H,3-5H2,(H,7,8)....
| Schlagworte: | 5-Hexynoate, ALK-4 |
| Anwendung: | Protein labeling compound, click chemistry |
| CAS | 53293-00-8 |
| MW: | 112.1 D |
ab 40,00 €
Lisuride (maleate)
Artikelnummer: Cay36140-1
An analytical reference standard categorized as a lysergamide, does not induce the HTR in mice, indicating a lack of hallucinogenic potential, intended for research and forensic applications. Formulation: A solid. InChI:...
| Schlagworte: | Lysenyl, N'-[(8a)-9,10-didehydro-6-methylergolin-8-yl]-N,N-diethyl-urea, 2Z-butenedioate |
| Anwendung: | Analytical reference standard, lysergamide |
| CAS | 19875-60-6 |
| MW: | 454.5 D |
ab 229,00 €
NPD4928
Artikelnummer: Cay36598-1
An FSP1 inhibitor and ferroptosis enhancer, binds to FSP1 and inhibits its activity in a cell-free NADH consumption assay, synergistically enhances RSL3-induced cytotoxicity in PANC-1 prostate cancer cells at 3 µM, induces cytotoxicity in PC3, MKN74, DU145, MIA PaCa-2, and A549 cells (IC50s = 95-155 nM,...
| Schlagworte: | 2-[(9,10-dihydro-3,4,8,8-tetramethyl-2-oxo-2H,8H-benzo[1,2-b:3,4-b']dipyran-5-yl)oxy]-N-[2-(5-methoxy-1H-indol-3-yl)ethyl]... |
| Anwendung: | FSP1 inhibitor, ferroptosis enhancer |
| CAS | 956965-61-0 |
| MW: | 504.57 D |
ab 76,00 €