Produkte von Cayman Chemical
Cayman Chemical Company ist ein Biotechunternehmen mit Sitz in Ann Arbor, Michigan, das 1980 von Kirk Maxey, M.D. gegründet wurde. Mit seinen biochemischen Produkten unterstützt Cayman Wissenschaftler*innen weltweit bei der Arbeit in den Forschungsfeldern Krebs, NO Signalling, Neurologie, Apoptose, oxidativer Stress, Endokrinologie und vielen weiteren. Cayman Chemical hat sich hierbei besonders auf die Herstellung von Assay-Kits zum Nachweis von Eicosanoiden, freien Radikalen, zyklischen Nukleotiden, Zytokinen, Hormonen und Stickstoffmonoxid spezialisiert. Neben diesen Kits bietet Cayman Chemical ein breites Angebot an Biochemikalien, darunter Eicosanoiden, NO Reagenzien sowie eine Reihe thematisch verwandter Lipide, Fettsäuren, Enzyme und Antikörper.
Mehr Informationen unter: www.caymanchem.com
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Anti-Glycine Receptor
Artikelnummer: Cay10009399-1
Glycine is an important inhibitory transmitter in the brain stem and spinal cord. Glycine receptors are members of the ligand-gated ion channel family (LGICs) that mediate rapid chemical neurotransmission. The binding of glycine to its receptor produces a large increase in chloride conductance, which causes membrane...
| Schlagworte: | Anti-Glyr, Anti-Glra1, Anti-Glycine receptor 48 kDa subunit, Anti-Glycine receptor subunit alpha-1, Anti-Glycine receptor... |
| Anwendung: | WB, IHC (frozen) |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, murine, rat |
645,00 €
Anti-Gap-43 (Phospho-Ser41)
Artikelnummer: Cay10009400-1
Gap-43 is thought to have an important role in development and plasticity because it is expressed at high levels in neuronal growth cones during development and during axonal regeneration. There is also evidence from knockout animals that Gap-43 serves to amplify path finding signals from the growth cone. Gap-43 is...
| Schlagworte: | Anti-phospho-Gap43, Anti-phospho-Protein F1, Anti-phospho-Neuromodulin, Anti-phospho-Growth-associated protein 43,... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | bovine, dog, chicken, human, murine |
645,00 €
Anti-ATF2 (Phospho-Ser490,498)
Artikelnummer: Cay10009410-1
The activating transcription factor 2 (ATF2, also called CRE-BP1) binds to both AP-1 and CRE DNA response elements and is a member of the ATF/CREB family of leucine zipper proteins. ATF2 has been implicated in the transcriptional regulation of a number of genes including cytokines, cell cycle control, and apoptosis....
| Schlagworte: | Activating Transcription Factor 2 |
| Anwendung: | WB, IHC (frozen) |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
645,00 €
Anti-Ribosomal S6 Kinase 2
Artikelnummer: Cay10009411-1
The p90 ribosomal S6 kinases (RSKs) 1-4 are downstream members of the extracellular signal-regulated kinase (ERK)/MAPK cascade. The loss of RSK2 activity in humans leads to Coffin-Lowry syndrome, which is characterized by mental retardation and growth deficits. Recent work suggests that RSK2 exerts a tonic...
| Schlagworte: | RSK2 |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | rat |
645,00 €
Anti-Tyrosine Hydroxylase (Phospho-Ser31)
Artikelnummer: Cay10009413-1
Tyrosine hydroxylase (TH) is the rate-limiting enzyme in the synthesis of the catecholamines dopamine and norepinephrine. TH antibodies can therefore be used as markers for dopaminergic and noradrenergic neurons in a variety of applications including depression, schizophrenia, Parkinson's disease, and drug abuse. TH...
| Schlagworte: | TH |
| Anwendung: | WB, IF (frozen), IHC (frozen) |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | rat |
645,00 €
Anti-Raf-1 (Phospho-Ser301)
Artikelnummer: Cay10009504-1
The Ras pathway is a critical signal transduction cascade involved in regulating cellular proliferation, differentiation, survival, and oncogenic transformation. Members of the Raf serine/threonine kinase family are key intermediates in this cascade, functioning to relay signals from activated Ras to the downstream...
| Schlagworte: | Anti-phospho-Raf, Anti-phospho-cRaf, Anti-phospho-Raf1, Anti-phospho-Raf-1, EC=2.7.11.1, Anti-phospho-Proto-oncogene... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | rat |
645,00 €
Anti-Raf-1 (Phospho-Ser642)
Artikelnummer: Cay10009505-1
The Ras pathway is a critical signal transduction cascade involved in regulating cellular proliferation, differentiation, survival, and oncogenic transformation. Members of the Raf serine/threonine kinase family are key intermediates in this cascade, functioning to relay signals from activated Ras to the downstream...
| Schlagworte: | Anti-phospho-Raf, Anti-phospho-cRaf, Anti-phospho-Raf1, Anti-phospho-Raf-1, EC=2.7.11.1, Anti-phospho-Proto-oncogene... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | rat |
645,00 €
Anti-PSD95
Artikelnummer: Cay10009506-1
PSD95 is a very prominent component of the postsynaptic densities of synapses. It contains three PDZ domains which play key roles in its interactions with other proteins in the synapse. It has been proposed that these PDZ domains organize glutamate receptors and their associated signaling proteins and determine the...
| Schlagworte: | Postsynaptic Density Protein of 95 |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | rat |
645,00 €
Anti-MEK1 (Phospho-Thr386)
Artikelnummer: Cay10009517-1
MAP kinase kinase 1 (MEK1) is an integral component of the MAP kinase cascade that regulates cell growth and differentiation . This pathway also plays a key role in synaptic plasticity in the brain . Activated MEK1 acts as a dual specificity kinase phosphorylating both a threonine and a tyrosine residue on MAP...
| Schlagworte: | MAP Kinase Kinase 1, MAPKK1, Mitogen-activated Protein Kinase Kinase 1 |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | rat |
645,00 €
Anti-MEK1 (Phospho-Thr292)
Artikelnummer: Cay10009518-1
MAP kinase kinase 1 (MAPKK1) is an integral component of the MAP kinase cascade that regulates cell growth and differentiation . This pathway also plays a key role in synaptic plasticity in the brain . Activated MEK1 acts as a dual specificity kinase phosphorylating both a threonine and a tyrosine residue on MAP...
| Schlagworte: | MAP Kinase Kinase 1, MAPKK1, Mitogen-activated Protein Kinase Kinase 1 |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
645,00 €
Anti-NMDA Receptor NR2B Subunit (Phospho-Tyr1252)
Artikelnummer: Cay10009759-1
The NMDA receptor (NMDAR) plays an essential role in memory, neuronal development, and it has also been implicated in several disorders of the central nervous system including Alzheimer's disease, epilepsy, and ischemic neuronal death. The NR1 protein can form NMDA activated channels when expressed in Xenopus...
| Schlagworte: | Anti-phospho-NR3, Anti-phospho-NR2B, Anti-phospho-hNR3, Anti-phospho-GRIN2B, Anti-phospho-NMDAR2B,... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
645,00 €
Anti-NMDA Receptor NR2B Subunit (Phospho-Tyr1336)
Artikelnummer: Cay10009760-1
The NMDA receptor (NMDAR) plays an essential role in memory, neuronal development, and it has also been implicated in several disorders of the central nervous system including Alzheimer's disease, epilepsy, and ischemic neuronal death. The NR1 protein can form NMDA activated channels when expressed in Xenopus...
| Schlagworte: | Anti-phospho-NR3, Anti-phospho-NR2B, Anti-phospho-hNR3, Anti-phospho-GRIN2B, Anti-phospho-NMDAR2B,... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
645,00 €