Produkte von Cayman Chemical
Cayman Chemical Company ist ein Biotechunternehmen mit Sitz in Ann Arbor, Michigan, das 1980 von Kirk Maxey, M.D. gegründet wurde. Mit seinen biochemischen Produkten unterstützt Cayman Wissenschaftler*innen weltweit bei der Arbeit in den Forschungsfeldern Krebs, NO Signalling, Neurologie, Apoptose, oxidativer Stress, Endokrinologie und vielen weiteren. Cayman Chemical hat sich hierbei besonders auf die Herstellung von Assay-Kits zum Nachweis von Eicosanoiden, freien Radikalen, zyklischen Nukleotiden, Zytokinen, Hormonen und Stickstoffmonoxid spezialisiert. Neben diesen Kits bietet Cayman Chemical ein breites Angebot an Biochemikalien, darunter Eicosanoiden, NO Reagenzien sowie eine Reihe thematisch verwandter Lipide, Fettsäuren, Enzyme und Antikörper.
Mehr Informationen unter: www.caymanchem.com
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N1,N11-Diethylnorspermine (hydrochloride)
Artikelnummer: Cay41393-10
An anticancer polyamine, inhibits the proliferation of PC3, TSU-pr1, DU145, and JCA-1 cells (IC50s = 65, 62, 3, and 21 µM, respectively), reduces ODC activity and increases diamine acetyltransferase 1 activity in PC3, DU145, and JCA-1 cells at 100 µM, increases H2O2 levels and disrupts the mitochondrial membrane...
| Schlagworte: | BE-333, DENSPM, N1,N11-Bis(ethyl)norspermine, N1,N3-bis[3-(ethylamino)propyl]-1,3-propanediamine, tetrahydrochloride |
| Anwendung: | Anticancer polyamine |
| CAS | 156886-85-0 |
| MW: | 390.3 D |
ab 40,00 €
Fluorescent Brightener 28
Artikelnummer: Cay41995-1
A fluorescent probe, has been used to image chitin in pale grass blue butterfly (Z. maha) wings and beta-glucans and glycans in the cell walls of cucumber plant stem and root tissues, displays an emission maximum of 430 nm upon excitation at 360 nm. Formulation: A solid. InChI:...
| Schlagworte: | C.I. 40622, Calcofluor White LRP, Calcofluor White M2R, Calcofluor White ST, Cellufluor, CFW, FB28, Fluostain I, UNPA-GX,... |
| Anwendung: | Fluorescent probe |
| CAS | 4193-55-9 |
| MW: | 960.9 D |
ab 45,00 €
KI-696
Artikelnummer: Cay42039-1
A Keap1-Nrf2 protein-protein interaction inhibitor, binds to the Keap1 Kelch domain (Kd = 1.3 nM) and increases the accumulation of Nrf2 in isolated human bronchial epithelial cells in a concentration-dependent manner, increases the expression of NQO1, GCLM, HMOX1, and TXNRD1 in bronchial epithelial cells isolated...
| Schlagworte: | betaS-[3-[[(4R)-3,4-dihydro-4-methyl-1,1-dioxido-2H-5,1,2-benzoxathiazepin-2-yl]methyl]-4-methylphenyl]-7-methoxy-1-methyl... |
| Anwendung: | Keap1-Nrf2 protein-protein interaction inhibitor |
| CAS | 1799974-70-1 |
| MW: | 550.63 D |
ab 60,00 €
FM(TM)1-43
Artikelnummer: Cay42094-1
A styryl dye and an inhibitor of mechanosensitive ion channels, reversibly binds to cell membranes and has been used to monitor synaptogenesis and reinnervation, endocytosis, and vacuole formation in vitro, inhibits rapidly and slowly adapting mechanically activated currents in both capsaicin-insensitive and...
| Schlagworte: | 4-[2-[4-(dibutylamino)phenyl]ethenyl]-1-[3-(triethylammonio)propyl]-pyridinium, dibromide |
| Anwendung: | Mechanosensitive ion channel inhibitor, styryl dye |
| CAS | 149838-22-2 |
| MW: | 611.5 D |
ab 83,00 €
H3B-8800
Artikelnummer: Cay42106-1
An inhibitor of the SF3B complex, binds to SF3B complexes containing wild-type SF3B (IC50 = 1.4 nM) or various SF3B mutations (IC50s = 0.3-1.8 nM), inhibits SF3B1-induced splicing of canonical and aberrant pre-mRNA junctions in HEK293T nuclear extracts overexpressing SF3B1K700E, selectively inhibits the growth of,...
| Schlagworte: | 4-methyl-1-piperazinecarboxylic acid,... |
| Anwendung: | SF3B complex inhibitor |
| CAS | 1825302-42-8 |
| MW: | 555.71 D |
ab 183,00 €
N-Lithocholyl-L-Alanine
Artikelnummer: Cay40929-100
A bile acid conjugate and an EPHA2 inhibitor (IC50 = 19.95 µM). Formulation: A solid. InChI: InChI=1S/C27H45NO4/c1-16(5-10-24(30)28-17(2)25(31)32)21-8-9-22-20-7-6-18-15-19(29)11-13-26(18,3)23(20)12-14-27(21,22)4/h16-23,29H,5-15H2,1-4H3,(H,28,30)(H,31,32)/t16-,17+,18-,19-,20+,21-,22+,23+,26+,27-/m1/s1. InChIKey:...
| Schlagworte: | N-[(3a,5beta)-3-hydroxy-24-oxocholan-24-yl]-L-alanine |
| Anwendung: | Bile acid conjugate, EPHA2 inhibitor |
| CAS | 1428095-28-6 |
| MW: | 447.65 D |
ab 110,00 €
CP-LC-1422
Artikelnummer: Cay41923-10
Lipid CP-LC-1422 is an ionizable cationic amino lipid derived from homocysteine, a naturally occurring amino acid. This lipid has demonstrated an efficient delivery and high protein expression of different kinds of RNA (mRNA, cRNA and saRNA) in vivo. Moreover, using a typical LNP formulation (IL/Ch/DOPE/PEG:...
| Anwendung: | Ionizable cationic amino lipid, homocysteine derivative |
| MW: | 976.53 D |
ab 229,00 €
Delta4-iso-THC
Artikelnummer: Cay33862-1
An analytical reference standard that is structurally similar to known phytocannabinoids, a potential impurity in the conversion of cannabidiol to Delta8-THC or Delta9-THC, has been found in Delta8-THC vape cartridges, intended for research and forensic applications. Formulation: A solution in acetonitrile. InChI:...
| Schlagworte: | Delta4-iso-Tetrahydrocannabinol, (2R,6R)-3,6-dihydro-2-methyl-5-(1-methylethyl)-9-pentyl-2,6-methano-2H-1-benzoxocin-7-ol |
| Anwendung: | Analytical reference standard, structurally similar to known phytocannabinoids |
| MW: | 314.5 D |
ab 95,00 €
hSMG-1 Inhibitor 11j
Artikelnummer: Cay41724-5
An SMG1 inhibitor (IC50 = 0.11 nM), selective for SMG1 over mTOR, Cdk1, Cdk2, PI3Kalpha, and PI3Kgamma (IC50s = 0.05, 32, 7.1, 0.092 and 0.06 µM, respectively) and a panel of 25 additional kinases (IC50s = >10 µM) but does inhibit GSKalpha and GSKbeta (IC50s = 0.26 and 0.33 µM, respectively), decreases the...
| Schlagworte: | 2-chloro-N,N-diethyl-5-[[4-[2-[4-[[(methylamino)carbonyl]amino]phenyl]-4-pyridinyl]-2-pyrimidinyl]amino]-benzenesulfonamide |
| Anwendung: | SMG1 inhibitor |
| CAS | 1402452-15-6 |
| MW: | 566.1 D |
ab 498,00 €
Tiglyl Glycine
Artikelnummer: Cay41836-5
An amino acid conjugate and intermediate in isoleucine catabolism, urinary levels are increased in patients with beta-ketothiolase deficiency, propionate metabolism disorders, or respiratory chain disorders. Formulation: A solid. InChI: InChI=1S/C7H11NO3/c1-3-5(2)7(11)8-4-6(9)10/h3H,4H2,1-2H3,(H,8,11)(H,9,10)/b5-3+....
| Schlagworte: | N-Tigloylglycine, N-[(2E)-2-methyl-1-oxo-2-buten-1-yl]-glycine |
| Anwendung: | Amino acid conjugate, isoleucine catabolism intermediate |
| CAS | 35842-45-6 |
| MW: | 157.2 D |
ab 55,00 €
BSA-Eicosapentaenoate Polyunsaturated Fatty Acid Complex...
Artikelnummer: Cay43473-5
A fatty acid substrate, can be used for efficient fatty acid delivery to cells in culture for monitoring fatty acid oxidation or similar processes in various cellular metabolic studies
| Schlagworte: | Bovine Serum Albumin-Eicosapentaenoate, Bovine Serum Albumin-EPA, BSA-EPA |
| Anwendung: | Fatty acid substrate, cell culture |
254,00 €
BSA-Oleate-d17 Monounsaturated Fatty Acid Complex (5 mM)
Artikelnummer: Cay43888-5
Protein function: Binds water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc. Major calcium and magnesium transporter in plasma, binds...
| Schlagworte: | BSA-OA-d17 |
| Anwendung: | Fatty acid substrate, cell culture |
| Exprimiert in: | Bovine |
319,00 €