Produkte von BPS Bioscience
Sonne, Meer und Wissenschaft: BPS Bioscience aus San Diego, Kalifornien fördert mit innovativen Lösungen für die Forschung neue wissenschaftliche Entdeckungen und die Entwicklung wirksamer Therapien. BPS ist ein Experte für rekombinante Proteine und Enzyme, Zelllinien, Virus-basierte Tools sowie für biochemische und zelluläre Assay-Systeme. Die hochwertigen Produkte und Services von BPS ermöglichen es Forschenden weltweit, biologische Entdeckungen in einer Vielzahl von Disziplinen voranzutreiben, darunter Epigenetik, Zellsignalübertragung, SARS-CoV-2, Immuntherapie, CRISPR und adoptive Zelltherapien.
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Futibatinib
Artikelnummer: BPS-83938-1
Futibatinib, also known as TAS-120 is an orally bioavailable, highly selective, and irreversible FGFR1-4 inhibitor, currently being used in the treatment of intrahepatic cholangiocarcinoma, a bile duct cancer in the liver. Fibroblast growth factor 21 (FGF-21) is a member of the FGF family that lacks the...
| Anwendung: | Cell based assays |
| CAS | 1448169-71-8 |
| MW: | 418.25 D |
ab 292,00 €
Icotrokinra
Artikelnummer: BPS-83942-1
Icotrokinra, also known as JNJ-77242113, is a selective antagonist of the IL-23 receptor, with anti-inflammatory properties. As of 2025 it was under regulatory review for the treatment of plaque psoriasis. Further applications can include UC (ulcerite colitis) and other autoimmune disorders. IL-23, a heterodimeric...
| Schlagworte: | IL23R, Interleukin-23 receptor |
| Anwendung: | Cell based assays |
| CAS | 2763602-16-8 |
| MW: | 1898.17 D |
ab 720,00 €
Zolbetuximab (Claudiximab)
Artikelnummer: BPS-83955-1
Zolbetuximab, also known as IMAB362 and Claudiximab, is a recombinant monoclonal antibody targeting claudin 18 isoform 2 (claudin 18-2). It is currently used in the treatment of gastric cancer. Claudins are integral membrane proteins and components of tight junction strands which serve as a physical barrier to...
| Schlagworte: | CLDN18, Claudin-18 |
| Anwendung: | ELISA, FC, FA |
| Wirt: | Human |
| Spezies-Reaktivität: | human |
| CAS | 1496553-00-4 |
ab 816,00 €
Gresonitamab (Anti-Human CD3xClaudin18 2)
Artikelnummer: BPS-83964-1
Gresonitamab, also known as AMG 910 is a half-life extended (HLE) bispecific T-cell engager (BiTE) antibody that targets CD3 in T cells and Claudin 18 isoform 2 (CLDN18.2) in cancer cells. Gresonitamab is being studied for cancer treatment. Claudins are integral membrane proteins and components of tight junction...
| Schlagworte: | CD3E, T-cell surface glycoprotein CD3 epsilon chain, T-cell surface antigen T3/Leu-4 epsilon chain |
| Anwendung: | ELISA, FC, FA |
| Wirt: | Human |
| Spezies-Reaktivität: | human |
| CAS | 2413817-97-5 |
ab 869,00 €
Nivolumab (Anti-PD-1 Antibody)
Artikelnummer: BPS-83965-1
Nivolumab, also known as BMS-936558, is a programmed death receptor-1 (PD-1) blocking human IgG4 antibody. This antibody is used in the treatment of several cancer types, from melanoma to Hodgkin lymphoma. PD-1 (Programmed Death Protein 1, CD279) is a transmembrane protein expressed on the surface of immune cells...
| Schlagworte: | PDCD1, Programmed cell death protein 1 |
| Anwendung: | ELISA, FC, FA |
| Wirt: | Human |
| Spezies-Reaktivität: | human |
| CAS | 946414-94-4 |
ab 774,00 €
Trastuzumab (Anti-HER2 Antibody)
Artikelnummer: BPS-83967-1
Trastuzumab is a humanized IgG1 recombinantmonoclonal antibody that selectively binds to HER2 (eceptor tyrosine-protein kinase ErbB-2) with high affinity. Trastuzumab can be used for the research of HER2-positive metastatic breast and gastric cancer. Trastuzumab consists of two antigen-specific sites that bind to...
| Schlagworte: | ERBB2, Receptor tyrosine-protein kinase erbB-2, Metastatic lymph node gene 19 protein, Proto-oncogene Neu, Proto-oncogene... |
| Anwendung: | ELISA, FC, FA |
| Wirt: | Human |
| Spezies-Reaktivität: | human |
| CAS | 180288-69-1 |
ab 560,00 €
Alirocumab Biosimilar (Human Proprotein Convertase...
Artikelnummer: BPS-83968-1
Alirocumab, also known as REGN 727, is a recombinant monoclonal antibody that targets PCSK9 (proprotein convertase subtilisin/kexin type 9). It increases the ability of the liver to bind LDL-cholesterol (LDL-C) and reduces levels of LDL-C in blood. Alirocumab improves atherosclerosis and inflammation and is used in...
| Schlagworte: | PCSK9, Proprotein convertase subtilisin/kexin type 9, Neural apoptosis-regulated convertase 1, Proprotein convertase 9,... |
| Anwendung: | ELISA, FC, FA |
| Wirt: | Human |
| Spezies-Reaktivität: | human |
| CAS | 1245916-14-6 |
ab 827,00 €
Narsoplimab (Anti-MASP2 Antibody)
Artikelnummer: BPS-83974-1
Narsoplimab, also known as OMS 721, is a high-affinity fully human immunoglobulin gamma 4 (IgG4) monoclonal antibody that binds to MASP2 (Mannan-binding lectin serine protease 2) and blocks lectin pathway activation. Narsoplimab can be used in research of hematopoietic stem-cell (HSC) transplantation and SARS-CoV-2....
| Schlagworte: | MASP2, Mannan-binding lectin serine protease 2, MBL-associated serine protease 2, Mannose-binding protein-associated... |
| Anwendung: | ELISA, FC, FA |
| Wirt: | Human |
| Spezies-Reaktivität: | human |
| CAS | 2108782-45-0 |
ab 869,00 €
CM-338 (Anti-MASP2 Antibody)
Artikelnummer: BPS-83977-1
M-338 is a human recombinant monoclonal antibody (mAb) targeting MASP2 (Mannan-binding lectin serine protease 2). CM-338 can be used in IgA nephropathy research. MASP2 (Mannan-binding lectin serine protease 2) is a serine protease involved in the activation of the lectin pathway (LP) of the complement system. The...
| Schlagworte: | MASP2, Mannan-binding lectin serine protease 2, MBL-associated serine protease 2, Mannose-binding protein-associated... |
| Anwendung: | ELISA, FC, FA |
| Wirt: | Human |
| Spezies-Reaktivität: | human |
| MW: | 143.44 kD |
ab 943,00 €
IL-9, His-Tag Recombinant
Artikelnummer: BPS-83983-1
Recombinant human Il-9 (interleukin-9), encompassing amino acids 19-144, corresponding to the mature full lenght protein. This construct contains a C-terminal His-tag (6xHis). This protein was affinity purified.
| Schlagworte: | IL9, Interleukin-9, Cytokine P40, T-cell growth factor P40 |
| Anwendung: | Cellular assays |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | ~25-40 kD |
ab 324,00 €
IDH1(R132H) Assay Kit
Artikelnummer: BPS-79376
The IDH1(R132H) Assay Kit is designed to measure IDH1(R132H) activity for screening and profiling applications by measuring NADPH consumption.
| Schlagworte: | Isocitrate Dehydrogenase 1, IDH1, Oxalosuccinate Decarboxylase, IDHM, |
| Anwendung: | Drug discovery, HTS |
| Spezies-Reaktivität: | human |
842,00 €
Anti-IL-31Ra Antibody
Artikelnummer: BPS-102378-1
Recombinant anti-IL-31Ra (interleukin 31 receptor subunit alpha) antibody recognizing human IL-31Ra protein. This anti-IL-31Ra antibody is a purified, humanized recombinant monoclonal antibody. This antibody has been tested in a binding assay. It is similar to Nemolizumab. IL-31 (interleukin 31) is a four-helix...
| Schlagworte: | IL31RA, Interleukin-31 receptor subunit alpha, Cytokine receptor-like 3, GLM-R, Gp130-like monocyte receptor, ZcytoR17 |
| Anwendung: | Binding assays |
| Wirt: | Human |
| Spezies-Reaktivität: | human |
ab 144,00 €
