Produkte von BPS Bioscience
Sonne, Meer und Wissenschaft: BPS Bioscience aus San Diego, Kalifornien fördert mit innovativen Lösungen für die Forschung neue wissenschaftliche Entdeckungen und die Entwicklung wirksamer Therapien. BPS ist ein Experte für rekombinante Proteine und Enzyme, Zelllinien, Virus-basierte Tools sowie für biochemische und zelluläre Assay-Systeme. Die hochwertigen Produkte und Services von BPS ermöglichen es Forschenden weltweit, biologische Entdeckungen in einer Vielzahl von Disziplinen voranzutreiben, darunter Epigenetik, Zellsignalübertragung, SARS-CoV-2, Immuntherapie, CRISPR und adoptive Zelltherapien.
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eGFP/Firefly Luciferase BCMA Knockout MM.1S Cell Line
Artikelnummer: BPS-82732
eGFP/Firefly Luciferase BCMA Knockout MM.1S Cell Line is a MM.1S cell Line constitutively expressing firefly (Photinus pyralis) luciferase and the enhanced GFP (eGFP) cassette under the control of a CMV promoter, where BCMA (B-Cell Maturation Antigen, or CD269) has been genetically removed using CRISPR/Cas9 genome...
| Schlagworte: | Luciferase, Luciferin 4-monooxygenase, |
| Anwendung: | Cell killing assay control, CAR-T / CAR-NK cell B-cell target , CAR design optimization |
| Spezies-Reaktivität: | human |
11.023,00 €
Chemi-Verse(TM) PDGFRalpha (D842I) Kinase Assay Kit
Artikelnummer: BPS-82752
The Chemi-Verse(TM) PDGFRalpha (D842I) Kinase Assay Kit is designed to measure PDGFRalpha (platelet-derived growth factor receptor A) (D842I) tyrosine kinase activity for screening and profiling applications using ADP-Glo(TM) as a detection reagent. The assay kit comes in a convenient 96-well format, with enough...
| Schlagworte: | CD140a, PDGFRA, PDGFR2, PDGFR-2, EC=2.7.10.1, PDGFR-alpha, PDGF-R-alpha, CD140a antigen, CD140 antigen-like family member... |
| Anwendung: | Enzyme kinetics, small molecule inhibitor screening, drug discovery, HTS |
| Spezies-Reaktivität: | human |
975,00 €
A-1155463
Artikelnummer: BPS-82803-1
A-1155463 is a highly potent and selective BCL-XL inhibitor with an EC50 of 70 nM in Molt-4 cell.1 A-1155463 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
| Schlagworte: | A-1155463, BCL-XL inhibitor, |
| Anwendung: | Apoptosis studies |
| CAS | 1235034-55-5 |
| MW: | 669,79 D |
ab 421,00 €
c-Myc: WDR5 [Biotinylated] Binding Chemiluminescent Assay...
Artikelnummer: BPS-82851
The c-Myc: WDR5 [Biotinylated] Binding Chemiluminescent Assay Kit is an ELISA designed to measure the binding between c-Myc and WDR5 (WD40 repeat domain 5) protein for screening and profiling applications. This kit comes with enough purified c-Myc (amino acids 2-454(end)) and biotinylated WDR5 (amino acids...
| Schlagworte: | MYC, bHLHe39, BHLHE39, Proto-oncogene c-Myc, Transcription factor p64, Myc proto-oncogene protein, Class E basic... |
| Anwendung: | Inhibitor studies, compound screening, drug discovery, HTS |
| Spezies-Reaktivität: | human |
2.341,00 €
B2M Knockout A549 Cell line
Artikelnummer: BPS-82871
B2M Knockout A549 Cell Line is an A549 cell line where B2M (Beta-2-Microglobulin) has been genetically removed by CRISPR/Cas9 genome editing.
| Schlagworte: | CDABP0092, |
| Anwendung: | B2M knock-down studies, T cell activation studies, antigen presentation, immune response |
| Spezies-Reaktivität: | human |
5.948,00 €
PDE4D7 Assay Kit
Artikelnummer: BPS-82885
The PDE4D7 Assay Kit is a fluorescence polarization (FP), homogeneous, 96-well assay kit designed for the screening and profiling of PDE4D7 (Phosphodiesterase 4D7) inhibitors. This assay takes advantage of a specific fluorescent phosphate-binding nanoparticle. The kit contains enough purified recombinant human...
| Schlagworte: | DPDE3, PDE43, cAMP-specific phosphodiesterase 4D, 3',5'-cyclic-AMP phosphodiesterase 4D, |
| Anwendung: | Enzyme kinetics, small molecule inhibitor screening, drug discovery, HTS |
| Spezies-Reaktivität: | human |
960,00 €
ADC Control Human IgG1-vcMMAE
Artikelnummer: BPS-82916-1
ADC Control Human IgG1-vcMMAE is a humanized monoclonal antibody that is an isotype control of ADC human IgG1-vcMMAE and can inhibit tubulin polymerization. The antibody portion is Human IgG1 kappa, Isotype Control, and the drug-linker conjugate for ADC is vcMMAE (HY-15575)1.
| Schlagworte: | Anti-Ig gamma-1 chain C region, Anti-Ig gamma-1 chain C region EU, Anti-Ig gamma-1 chain C region KOL, Anti-Ig gamma-1... |
| Anwendung: | Cancer therapy target studies |
| Spezies-Reaktivität: | human |
ab 1.781,00 €
ADC Control Human IgG1-vcMMAF
Artikelnummer: BPS-82917-1
ADC Control Human IgG1-vcMMAF is a humanized monoclonal antibody that is an isotype control of ADC human IgG1-vcMMAF and can inhibit tubulin polymerization. The antibody portion is Human IgG1 kappa, Isotype Control, and the drug-linker conjugate for ADC is MC-Val-Cit-PAB-MMAF1.
| Schlagworte: | Anti-Ig gamma-1 chain C region, Anti-Ig gamma-1 chain C region EU, Anti-Ig gamma-1 chain C region KOL, Anti-Ig gamma-1... |
| Anwendung: | Cancer therapy target studies |
| Spezies-Reaktivität: | human |
ab 1.894,00 €
Loncastuximab Tesirine
Artikelnummer: BPS-82918-1
Loncastuximab tesirine is a human cluster of differentiation 19 (CD19)-directed antibody-drug conjugate (ADC). Once bound to CD19 on the cell membrane, loncastuximab tesirine is rapidly internalised and triggers cell death. Loncastuximab tesirin induces cell apoptosis, it can be used for the research of diffuse...
| Schlagworte: | Anti-CD19, Anti-B-lymphocyte antigen CD19, Anti-Differentiation antigen CD19, Anti-T-cell surface antigen Leu-12,... |
| Anwendung: | Cancer therapy target studies |
| Spezies-Reaktivität: | human |
| CAS | 1879918-31-6 |
| MW: | ~147 kD |
ab 1.997,00 €
Epratuzumab Tesirine
Artikelnummer: BPS-82919-1
Epratuzumab Tesirine (ADCT-602) is a novel CD22-targeted ADC. Epratuzumab Tesirine contains a PBD dimer and a payload SG32491.
| Schlagworte: | Anti-CD22, Anti-BL-CAM, Anti-SIGLEC2, Anti-Siglec-2, Anti-B-cell receptor CD22, Anti-T-cell surface antigen Leu-14,... |
| Anwendung: | Cancer therapy target studies |
| Spezies-Reaktivität: | human |
ab 8.850,00 €
Telisotuzumab Vedotin
Artikelnummer: BPS-82922-1
Telisotuzumab vedotin (ABBV-399) is an antibody-drug conjugate (ADCs) targeting c-Met. Telisotuzumab vedotin consists of Monomethyl Auristatin E (MMAE), Telisotuzumab antibody and a cleavable mc-val-cit-PABC type linker. Telisotuzumab vedotin can be used to study non-small cell lung cancer expressing c-Met protein1,2.
| Schlagworte: | Anti-MET, Anti-SF receptor, EC=2.7.10.1, Anti-HGF receptor, Anti-HGF/SF receptor, Anti-Proto-oncogene c-Met, Anti-Scatter... |
| Anwendung: | Cancer therapy target studies |
| Spezies-Reaktivität: | human |
| CAS | 1714088-51-3 |
| MW: | ~145 kD |
ab 805,00 €
Trastuzumab Emtansine
Artikelnummer: BPS-82923-1
Trastuzumab emtansine (Ado-Trastuzumab emtansine) is an antibody-drug conjugate (ADC) that incorporates the HER2-targeted antitumor properties of trastuzumab with the cytotoxic activity of the microtubule-inhibitory agent DM1 (derivative of maytansine). Trastuzumab emtansine can be used for the research of advanced...
| Schlagworte: | Anti-HER2, Anti-CD340, Anti-ERBB2, Anti-MLN 19, Anti-p185erbB2, EC=2.7.10.1, Anti-Proto-oncogene Neu, Anti-Proto-oncogene... |
| Anwendung: | Cancer therapy target studies |
| Spezies-Reaktivität: | human |
| CAS | 1018448-65-1 |
| MW: | ~148 kD |
ab 1.915,00 €
