Produkte von BPS Bioscience
Sonne, Meer und Wissenschaft: BPS Bioscience aus San Diego, Kalifornien fördert mit innovativen Lösungen für die Forschung neue wissenschaftliche Entdeckungen und die Entwicklung wirksamer Therapien. BPS ist ein Experte für rekombinante Proteine und Enzyme, Zelllinien, Virus-basierte Tools sowie für biochemische und zelluläre Assay-Systeme. Die hochwertigen Produkte und Services von BPS ermöglichen es Forschenden weltweit, biologische Entdeckungen in einer Vielzahl von Disziplinen voranzutreiben, darunter Epigenetik, Zellsignalübertragung, SARS-CoV-2, Immuntherapie, CRISPR und adoptive Zelltherapien.
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Farletuzumab Ecteribulin
Artikelnummer: BPS-82929-1
Farletuzumab ecteribulin (MORAb-202) is an antibody-drug conjugate (ADC), consisting of the humanized anti-human folate receptor alpha (FRA) antibody Farletuzumab conjugated via reduced interchain disulfide bonds to Mal-PEG2-Val-Cit-PAB-eribulin. Farletuzumab ecteribulin has a agent-to-antibody ratio of 4.0....
| Schlagworte: | Anti-FBP, Anti-FOLR, Anti-FOLR1, Anti-FR-alpha, Anti-KB cells FBP, Anti-Folate receptor 1, Anti-Folate receptor alpha,... |
| Anwendung: | Cancer therapy target studies |
| Spezies-Reaktivität: | human |
| CAS | 2407465-18-1 |
| MW: | ~149 kD |
ab 2.761,00 €
Cofetuzumab Pelidotin
Artikelnummer: BPS-82930-1
Cofetuzumab pelidotin (PF-06647020) is a PTK7-targeting ADC comprising a humanized anti-PTK7 mAb (hu6M024, IgG1) joined to an auristatin microtubule inhibitor payload, auristatin-0101 (Aur0101), by a cleavable valine-citrulline (vc)-based linker. Cofetuzumab pelidotin has a DAR of 4. Cofetuzumab pelidotin binds to...
| Schlagworte: | Anti-PTK7, Anti-CCK4, Anti-CCK-4, Anti-Colon carcinoma kinase 4, Anti-Protein-tyrosine kinase 7, Anti-Tyrosine-protein... |
| Anwendung: | Cancer therapy target studies |
| Spezies-Reaktivität: | human |
| CAS | 1869937-48-3 |
ab 1.594,00 €
SGN-B6A
Artikelnummer: BPS-82933-1
SGN-B6A is an ADC, which targets integrin beta-6 (ITGB6) through human IgG1 monoclonal antibody Sigvotatug, and exhibits cytotoxicity against multiple integrin beta-6-positive cancer cell through mitotic inhibitor MMAE1.
| Schlagworte: | Anti-ITGB6, Anti-Integrin beta-6, |
| Anwendung: | Cancer therapy target studies |
| Spezies-Reaktivität: | human |
ab 2.069,00 €
Tusamitamab Ravtansine
Artikelnummer: BPS-82934-1
Tusamitamab ravtansine (SAR-408701) is a targeted ADC against tumor cells expressing CEACAM5, composed of a humanized anti-CEACAM5 monoclonal antibody covalently linked to the potent cytotoxic agent, maytansinoid DM4 , via a cleavable linker. Tusamitamab ravtansine has an average drug-to-antibody ratio (DAR) of...
| Schlagworte: | Anti-CEA, Anti-CD66e, Anti-Meconium antigen 100, Anti-Carcinoembryonic antigen, Anti-CEA cell adhesion molecule 5,... |
| Anwendung: | Cancer therapy target studies |
| Spezies-Reaktivität: | human |
| CAS | 2254086-60-5 |
ab 2.253,00 €
ORM-5029
Artikelnummer: BPS-82935-1
ORM-5029 is a first-in-class human epidermal growth factor receptor 2 (HER2)-targeted antibody-drug conjugate (ADC) comprised of SMol006, a highly potent GSPT1 degrader, conjugated to Pertuzumab. ORM-5029 can be used for study of cancer1.
| Schlagworte: | Anti-HER2, Anti-CD340, Anti-ERBB2, Anti-MLN 19, Anti-p185erbB2, EC=2.7.10.1, Anti-Proto-oncogene Neu, Anti-Proto-oncogene... |
| Anwendung: | Cancer therapy target studies |
| Spezies-Reaktivität: | human |
ab 3.072,00 €
Assay Medium 1E
Artikelnummer: BPS-82938-1
This liquid assay medium is optimized for use in cellular assays in select BPS Bioscience cell lines.
| Anwendung: | Cellular assay medium |
ab 197,00 €
Human TCRalpha/beta T Cell Depletion Kit
Artikelnummer: BPS-82941-1
The Human TCRalpha/beta T Cell Depletion Kit is designed to magnetically deplete human TCRalpha/beta+ T cells from a complex immune cell population. This kit is optimized for the positive selection of TCRalpha/beta T cells from normal human peripheral blood mononuclear cells (PBMCs). First, TCRalpha/beta+ cells are...
| Schlagworte: | pTa, pT-alpha, pT-alpha-TCR, Pre T-cell antigen receptor alpha, |
| Anwendung: | TCRalpha/beta+ T cells depletion/isolation |
| Spezies-Reaktivität: | human |
ab 220,00 €
HLA-A/B/C Knockout HEK293T Cell Line
Artikelnummer: BPS-82943
The HLA-A/B/C Knockout HEK293T Cell Line is a clonal HEK293T cell line that does not express Human Leukocyte Antigen (HLA)-A, HLA-B, and HLA-C. This knockout cell line was generated by CRISPR/Cas9 genome editing using sgRNAs that target regions common to all three genes. This cell line has been validated by flow...
| Schlagworte: | HLAA, HLA-A, Human leukocyte antigen A, HLA class I histocompatibility antigen, A alpha chain, |
| Anwendung: | Specific HLA-A, B, or C allele expression, antigen presentation |
| Spezies-Reaktivität: | human |
9.955,00 €
Loncastuximab Tesirine
Artikelnummer: BPS-82918-1
Loncastuximab tesirine is a human cluster of differentiation 19 (CD19)-directed antibody-drug conjugate (ADC). Once bound to CD19 on the cell membrane, loncastuximab tesirine is rapidly internalised and triggers cell death. Loncastuximab tesirin induces cell apoptosis, it can be used for the research of diffuse...
| Schlagworte: | Anti-CD19, Anti-B-lymphocyte antigen CD19, Anti-Differentiation antigen CD19, Anti-T-cell surface antigen Leu-12,... |
| Anwendung: | Cancer therapy target studies |
| Spezies-Reaktivität: | human |
| CAS | 1879918-31-6 |
| MW: | ~147 kD |
ab 1.997,00 €
KAT6B (MORF), FLAG-Tag Recombinant
Artikelnummer: BPS-102175
Recombinant human KAT6B (lysine acetyltransferase 6B) isoform 1, also known as MORF, encompassing amino acids 710-1020. This construct contains the catalytic domain and an N-terminal FLAG-tag. The recombinant protein was affinity purified.
| Schlagworte: | KAT6B, MYST-4, KIAA0383, Histone acetyltransferase MOZ2, Histone acetyltransferase KAT6B, MOZ, YBF2/SAS3, SAS2 and TIP60... |
| Anwendung: | Acetylation assays |
| Exprimiert in: | human cells |
| Ursprungsart: | human |
| MW: | 38 kD |
678,00 €
PARP1 (Mouse), GST-Tag Recombinant
Artikelnummer: BPS-102596-1
Recombinant mouse PARP1 (poly-(ADP-ribose) polymerase 1), full-length, encompassing amino acids 2-1014(end). This construct contains an N-terminal GST-tag followed by a Thrombin Cleavage Site. The recombinant protein was affinity purified.
| Schlagworte: | Adprp, Parp1, |
| Anwendung: | Enzyme kinetics, inhibitor screening, selectivity profiling |
| Exprimiert in: | insect cells |
| Ursprungsart: | mouse |
| MW: | 139 kD |
ab 446,00 €
CD125 (IL-5Ra), N-Terminal Avi-Tag, Fc-Fusion (lgG1),...
Artikelnummer: BPS-102645-1
Recombinant CD125, or IL-5Ra (Interleukin 5 receptor subunit alpha), transcript variant 1, encompassing amino acids 21-342. The protein is fused at the N-terminus with an Avi-Tag(TM) followed by the Fc fragment of a human IgG1. The recombinant protein was affinity purified.
| Schlagworte: | IL5R, IL5RA, CD125, CDw125, IL-5RA, IL-5R-alpha, IL-5R subunit alpha, IL-5 receptor subunit alpha, Interleukin-5 receptor... |
| Anwendung: | Binding assays |
| Exprimiert in: | human cells |
| Ursprungsart: | human |
| MW: | 65+glyc kD |
ab 416,00 €
