Produkte von BPS Bioscience
Sonne, Meer und Wissenschaft: BPS Bioscience aus San Diego, Kalifornien fördert mit innovativen Lösungen für die Forschung neue wissenschaftliche Entdeckungen und die Entwicklung wirksamer Therapien. BPS ist ein Experte für rekombinante Proteine und Enzyme, Zelllinien, Virus-basierte Tools sowie für biochemische und zelluläre Assay-Systeme. Die hochwertigen Produkte und Services von BPS ermöglichen es Forschenden weltweit, biologische Entdeckungen in einer Vielzahl von Disziplinen voranzutreiben, darunter Epigenetik, Zellsignalübertragung, SARS-CoV-2, Immuntherapie, CRISPR und adoptive Zelltherapien.
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B2M Knockout A549 Cell line
Artikelnummer: BPS-82871
B2M Knockout A549 Cell Line is an A549 cell line where B2M (Beta-2-Microglobulin) has been genetically removed by CRISPR/Cas9 genome editing.
| Schlagworte: | CDABP0092, |
| Anwendung: | B2M knock-down studies, T cell activation studies, antigen presentation, immune response |
| Spezies-Reaktivität: | human |
5.948,00 €
PDE4D7 Assay Kit
Artikelnummer: BPS-82885
The PDE4D7 Assay Kit is a fluorescence polarization (FP), homogeneous, 96-well assay kit designed for the screening and profiling of PDE4D7 (Phosphodiesterase 4D7) inhibitors. This assay takes advantage of a specific fluorescent phosphate-binding nanoparticle. The kit contains enough purified recombinant human...
| Schlagworte: | DPDE3, PDE43, cAMP-specific phosphodiesterase 4D, 3',5'-cyclic-AMP phosphodiesterase 4D, |
| Anwendung: | Enzyme kinetics, small molecule inhibitor screening, drug discovery, HTS |
| Spezies-Reaktivität: | human |
960,00 €
Chemi-Verse(TM) FRK Kinase Assay Kit
Artikelnummer: BPS-82898
The Chemi-Verse(TM) FRK Kinase Assay Kit is designed to measure FRK (Fyn-related kinase) tyrosine kinase activity for screening and profiling applications using ADP-Glo(TM) as a detection reagent. The assay kit comes in a convenient 96-well format, with enough purified recombinant FRK kinase (amino acids 208-505),...
| Schlagworte: | FRK, PTK5, EC=2.7.10.2, FYN-related kinase, Protein-tyrosine kinase 5, Tyrosine-protein kinase FRK, Nuclear tyrosine... |
| Anwendung: | Enzyme kinetics, small molecule inhibitor screening, drug discovery, HTS |
| Spezies-Reaktivität: | human |
819,00 €
ADC Control Human IgG1-vcMMAE
Artikelnummer: BPS-82916-1
ADC Control Human IgG1-vcMMAE is a humanized monoclonal antibody that is an isotype control of ADC human IgG1-vcMMAE and can inhibit tubulin polymerization. The antibody portion is Human IgG1 kappa, Isotype Control, and the drug-linker conjugate for ADC is vcMMAE (HY-15575)1.
| Schlagworte: | Anti-Ig gamma-1 chain C region, Anti-Ig gamma-1 chain C region EU, Anti-Ig gamma-1 chain C region KOL, Anti-Ig gamma-1... |
| Anwendung: | Cancer therapy target studies |
| Spezies-Reaktivität: | human |
ab 1.781,00 €
ADC Control Human IgG1-vcMMAF
Artikelnummer: BPS-82917-1
ADC Control Human IgG1-vcMMAF is a humanized monoclonal antibody that is an isotype control of ADC human IgG1-vcMMAF and can inhibit tubulin polymerization. The antibody portion is Human IgG1 kappa, Isotype Control, and the drug-linker conjugate for ADC is MC-Val-Cit-PAB-MMAF1.
| Schlagworte: | Anti-Ig gamma-1 chain C region, Anti-Ig gamma-1 chain C region EU, Anti-Ig gamma-1 chain C region KOL, Anti-Ig gamma-1... |
| Anwendung: | Cancer therapy target studies |
| Spezies-Reaktivität: | human |
ab 1.894,00 €
Epratuzumab Tesirine
Artikelnummer: BPS-82919-1
Epratuzumab Tesirine (ADCT-602) is a novel CD22-targeted ADC. Epratuzumab Tesirine contains a PBD dimer and a payload SG32491.
| Schlagworte: | Anti-CD22, Anti-BL-CAM, Anti-SIGLEC2, Anti-Siglec-2, Anti-B-cell receptor CD22, Anti-T-cell surface antigen Leu-14,... |
| Anwendung: | Cancer therapy target studies |
| Spezies-Reaktivität: | human |
ab 8.850,00 €
Datopotamab Deruxtecan
Artikelnummer: BPS-82921-1
Datopotamab deruxtecan (DS-1062, Dato-DXd) is a trophoblast cell surface antigen 2 (TROP2)-directed antibody-drug conjugate (ADC). Datopotamab deruxtecan has a potent antitumor activity.1
| Schlagworte: | Anti-TACSTD2, Anti-GA733-1, Anti-Cell surface glycoprotein Trop-2, Anti-Pancreatic carcinoma marker protein GA733-1,... |
| Anwendung: | Cancer therapy target studies |
| Spezies-Reaktivität: | human |
| CAS | 2238831-60-0 |
| MW: | ~149 kD |
ab 2.921,00 €
Telisotuzumab Vedotin
Artikelnummer: BPS-82922-1
Telisotuzumab vedotin (ABBV-399) is an antibody-drug conjugate (ADCs) targeting c-Met. Telisotuzumab vedotin consists of Monomethyl Auristatin E (MMAE), Telisotuzumab antibody and a cleavable mc-val-cit-PABC type linker. Telisotuzumab vedotin can be used to study non-small cell lung cancer expressing c-Met protein1,2.
| Schlagworte: | Anti-MET, Anti-SF receptor, EC=2.7.10.1, Anti-HGF receptor, Anti-HGF/SF receptor, Anti-Proto-oncogene c-Met, Anti-Scatter... |
| Anwendung: | Cancer therapy target studies |
| Spezies-Reaktivität: | human |
| CAS | 1714088-51-3 |
| MW: | ~145 kD |
ab 805,00 €
Trastuzumab Emtansine
Artikelnummer: BPS-82923-1
Trastuzumab emtansine (Ado-Trastuzumab emtansine) is an antibody-drug conjugate (ADC) that incorporates the HER2-targeted antitumor properties of trastuzumab with the cytotoxic activity of the microtubule-inhibitory agent DM1 (derivative of maytansine). Trastuzumab emtansine can be used for the research of advanced...
| Schlagworte: | Anti-HER2, Anti-CD340, Anti-ERBB2, Anti-MLN 19, Anti-p185erbB2, EC=2.7.10.1, Anti-Proto-oncogene Neu, Anti-Proto-oncogene... |
| Anwendung: | Cancer therapy target studies |
| Spezies-Reaktivität: | human |
| CAS | 1018448-65-1 |
| MW: | ~148 kD |
ab 1.915,00 €
Trastuzumab Duocarmazine
Artikelnummer: BPS-82924-1
Trastuzumab duocarmazine ((vic)-Trastuzumab duocarmazine) is a HER2-targeting ADC that is recognized and cleaved by histone B in tumor cells and selectively targets tumor cells. Trastuzumab duocarmazine has anti-tumor activity and can be used in cancer research related to uterine and ovarian sarcomas1.
| Schlagworte: | Anti-HER2, Anti-CD340, Anti-ERBB2, Anti-MLN 19, Anti-p185erbB2, EC=2.7.10.1, Anti-Proto-oncogene Neu, Anti-Proto-oncogene... |
| Anwendung: | Cancer therapy target studies |
| Spezies-Reaktivität: | human |
| CAS | 1642152-40-6 |
| MW: | ~149 kD |
ab 2.233,00 €
Depatuxizumab MMAE
Artikelnummer: BPS-82927-1
Depatuxizumab MMAE is an antibody-drug conjugate (ADC) comprising an anti EGFR monoclonal antibody (Depatuxizumab) and the cytotoxic agent Monomethyl auristatin E (MMAE). Depatuxizumab inhibits the growth of xenograft models of mutant EGFRvIII and wild-type EGFR1.
| Schlagworte: | Anti-ERBB, EC=2.7.10.1, Anti-Proto-oncogene c-ErbB-1, Anti-Epidermal growth factor receptor, Anti-Receptor... |
| Anwendung: | Cancer therapy target studies |
| Spezies-Reaktivität: | human |
ab 1.573,00 €
Trastuzumab MMAE
Artikelnummer: BPS-82928-1
Trastuzumab MMAE is an anti-human epidermal growth factor receptor 2 (HER2) antibody-drug conjugate (ADC). Trastuzumab MMAE is composed of a humanized anti-HER2 antibody Trastuzumab, an enzymatically cleavable peptide-linker Valine-citrulline, a tubulin inhibitor Monomethyl auristatin E (MMAE). Trastuzumab MMAE can...
| Schlagworte: | Anti-HER2, Anti-CD340, Anti-ERBB2, Anti-MLN 19, Anti-p185erbB2, EC=2.7.10.1, Anti-Proto-oncogene Neu, Anti-Proto-oncogene... |
| Anwendung: | Cancer therapy target studies |
| Spezies-Reaktivität: | human |
ab 869,00 €
