Produkte von BPS Bioscience
Sonne, Meer und Wissenschaft: BPS Bioscience aus San Diego, Kalifornien fördert mit innovativen Lösungen für die Forschung neue wissenschaftliche Entdeckungen und die Entwicklung wirksamer Therapien. BPS ist ein Experte für rekombinante Proteine und Enzyme, Zelllinien, Virus-basierte Tools sowie für biochemische und zelluläre Assay-Systeme. Die hochwertigen Produkte und Services von BPS ermöglichen es Forschenden weltweit, biologische Entdeckungen in einer Vielzahl von Disziplinen voranzutreiben, darunter Epigenetik, Zellsignalübertragung, SARS-CoV-2, Immuntherapie, CRISPR und adoptive Zelltherapien.
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MAT2A Inhibitor Screening Assay Kit
Artikelnummer: BPS-71402-1
The MAT2a Inhibitor Screening Assay Kit is designed to measure MAT2A activity for screening and profiling applications. The MAT2A assay kit comes in a convenient 384-well format, with purified recombinant MAT2A enzyme, L-Methionine, ATP, MAT2A assay buffer, and Colorimetric detection reagent for 384 enzyme reactions.
| Schlagworte: | AMS2, MAT2A, MAT 2, MAT-II, AdoMet synthase 2, Methionine adenosyltransferase 2, Methionine adenosyltransferase II,... |
| Anwendung: | Enzyme kinetics, drug discovery, HTS |
| Spezies-Reaktivität: | human |
ab 1.049,00 €
Androgen Receptor Luciferase Reporter Lentivirus
Artikelnummer: BPS-78763
Androgen Receptor Luciferase Reporter Lentivirus are replication incompetent, HIV-based, VSV-G pseudotyped lentiviral particles that are ready to transduce most mammalian cells, including primary and non-dividing cells. These viruses contain a firefly luciferase reporter driven by multiple copies of androgen...
| Schlagworte: | androgen, AR, Dihydrotestosterone, DHT, prostate cancer, conditional luciferase reporter, NR3C4, castration,... |
| Anwendung: | Modulator screening/characterization, cell pool/stable cell line generation |
1.417,00 €
Estrogen Response Element (ERE) Luciferase Reporter...
Artikelnummer: BPS-78764
Estrogen Response Element (ERE) Luciferase Reporter Lentivirus are replication incompetent, HIV-based, VSV-G pseudotyped lentiviral particles that are ready to transduce most mammalian cells, including primary and non-dividing cells. These viruses contain a firefly luciferase reporter driven by multiple copies of...
| Schlagworte: | Estrogen Response Element, ERE, ER, estrogen receptor, |
| Anwendung: | Modulator screening/characterization, cell pool/stable cell line generation |
1.270,00 €
PD-1 Lentivirus
Artikelnummer: BPS-82348
The PD-1 Lentivirus are replication incompetent, HIV-based, VSV-G pseudotyped lentiviral particles ready to transduce almost all types of mammalian cells, including primary and non-dividing cells. These viruses transduce cells with human PD-1 (Programmed Death Protein 1) (NM_005018.3) driven by a CMV promoter. The...
| Schlagworte: | PD-1, PD1, Programmed Death 1, |
| Anwendung: | Human PD-1 expression in cells of interest, cell pool/stable cell line (Blasticidin selection) |
1.417,00 €
Estrogen Luciferase Reporter T47D Cell Line
Artikelnummer: BPS-82349
Estrogen Luciferase Reporter T47D Cell Line is a human breast cancer, ERalpha (estrogen receptor alpha)-positive luminal A cell line, with a stably integrated Firefly luciferase reporter under the control of an estrogen response element (ERE). This cell line monitors the activity of the ER signaling pathway. This...
| Schlagworte: | Estrogen receptor, ER-alpha, Estradiol receptor, Nuclear receptor subfamily 3 group A member 1, ESR1, ESR, NR3A1, |
| Anwendung: | Modulator screening/characterization, otential drug candidate evaluation (ER-directed therapies) |
3.959,00 €
NF-kappaB Luciferase-eGFP Reporter HEK293 Cell Line
Artikelnummer: BPS-82389
NF-kappaB Luciferase-eGFP Reporter HEK293 Cell Line is a HEK293 cell line designed to monitor nuclear factor Kappa B (NF-kappaB) activity. It contains a firefly luciferase-eGFP (enhanced green fluorescent protein) reporter driven by multiple copies of the NF-kappaB response element located upstream of the minimal...
| Schlagworte: | NF-kB reporter, NFkappaB reporter, NFkB, nfkb, nf-kb, |
| Anwendung: | NF-kappaB activity monitoring, NF-kappaB signaling pathway agent screeninng/characterization |
2.569,00 €
MAGE-A4 TCR-T Cells
Artikelnummer: BPS-82390
The MAGE-A4 TCR-T Cells are generated by high-titer lentiviral transduction of human primary CD4+ and CD8+ T cells with MAGE-A4-Specific TCR Lentivirus (#78935). These ready-to-use TCR (T cell receptor)-T cells express the human TCR that specifically recognizes antigen MAGE-A4 (Melanoma-associated antigen 4). These...
| Schlagworte: | MAGEA4, Melanoma-associated antigen 4, Cancer/testis antigen 1.4 (CT1.4), MAGE-4 antigen, MAGE-41 antigen, MAGE-X2... |
| Anwendung: | Positive control, MAGE-A4 TCR-T cell-driven cytotoxicity modulator screening |
2.710,00 €
PRAME TCR-T cells
Artikelnummer: BPS-82391
The PRAME TCR-T Cells are generated by high-titer lentiviral transduction of human primary CD4+ and CD8+ T cells with PRAME-Specific TCR Lentivirus (#78959). These ready-to-use TCR (T cell receptor)-T cells express the human TCR that specifically recognizes antigen PRAME (Preferentially Expressed Antigen in...
| Schlagworte: | Opa-interacting protein 4, OIP-4 1, publication Preferentially expressed antigen of melanoma, MAPE, |
| Anwendung: | Positive control, PRAME TCR-T cell-driven cytotoxicity modulator screening |
2.710,00 €
TCR Knockout Electroporation Kit
Artikelnummer: BPS-82394
The TCR Knockout Electroporation Kit is suitable for Jurkat cell line and primary T cell engineering using electroporation. The kit contains both the Cas9 enzyme (Streptococcus pyogenes) and the gRNAs targeting TRAC (T-Cell Receptor Alpha Constant) and TRBC (targets both T Cell Receptor Beta Constant 1 and T Cell...
| Schlagworte: | CRISPR, TCR knockout, CAR-T, T cell receptor, |
| Anwendung: | TCR alpha/beta knockout in cells of interest |
461,00 €
Untransduced T Cells (MAGE-A4 TCR-T Negative Control)
Artikelnummer: BPS-82396
The Untransduced T Cells (MAGE-A4 TCR-T Negative Control) were produced by mock lentiviral transduction of human primary CD4+ and CD8+ T cells. These cells are subjected to comparable manipulations as TCR (T cell receptor)-T cells: activation, spinoculation (without lentivirus), and antigen specific stimulation....
| Schlagworte: | MAGEA4, Melanoma-associated antigen 4, Cancer/testis antigen 1.4 (CT1.4), MAGE-4 antigen, MAGE-41 antigen, MAGE-X2... |
| Anwendung: | Negative control (lentivirus-transduced TCR-T cells expressing MAGE-A4) |
1.417,00 €
Untransduced T Cells (PRAME TCR-T Negative Control)
Artikelnummer: BPS-82397
The Untransduced T Cells (PRAME TCR-T Negative Control) were produced by mock lentiviral transduction of human primary CD4+ and CD8+ T cells. These cells are subjected to comparable manipulations as TCR (T cell receptor)-T cells: activation, spinoculation (without lentivirus), and antigen specific stimulation. These...
| Schlagworte: | PRAME, MAPE. OIP4, Opa-interacting protein 4, Preferentially expressed antigen of melanoma,, |
| Anwendung: | Negative control (lentivirus-transduced PRAME TCR-T cells) |
1.417,00 €
KRAS (G12C) Isoform A Coupled Nucleotide Exchange...
Artikelnummer: BPS-82709
The KRAS (G12C) Isoform A Coupled Nucleotide Exchange TR-FRET Assay Kit is a TR-FRET (Time-Resolved Fluorescence Resonance Energy Transfer) assay kit designed for screening and profiling of KRAS (Kirsten rat sarcoma) (G12C) antagonists/inhibitors. It monitors the binding of an effector protein such as the Ras...
| Schlagworte: | KRAS2, RASK2, |
| Anwendung: | Small molecule inhibitor/antagonist screening, HTS |
1.708,00 €
