Produkte von BellBrook Labs

BellBrook Labs

BellBrook Labs ist ein führender Anbieter von biochemischen Assay-Lösungen für die Wirkstoffforschung und Enzymanalyse. Das Unternehmen entwickelt und vertreibt innovative High-Throughput-Screening-(HTS)-Assays, validierte Enzyme sowie passende Reagenzien und unterstützt Kunden zusätzlich mit Assayentwicklung, Workflow-Validierung und wissenschaftlichen Dienstleistungen. Mit den proprietären Plattformen Transcreener® und AptaFluor® ermöglicht BellBrook Labs sensitive, robuste und anwenderfreundliche Messverfahren für ein breites Spektrum enzymatischer Targets in Pharma-, Biotech- und akademischen Forschungseinrichtungen.

Mehr Informationen unter: www.bellbrooklabs.com

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Transcreener(R) cGAMP cGAS FP Assay
Transcreener(R) cGAMP cGAS FP Assay

Artikelnummer: BBL-3024-10K

The Transcreener(R) cGAMP cGAS FP Assay is a far-red, competitive fluorescence polarization (FP) assay. The Transcreener(R) assay is designed specifically for high throughput screening (HTS), with a single addition, mix-and-read format. Because the antibody is highly selective for cGAMP, the assay can be used to...
Schlagworte: cGAS Activity Assay, cGAS Inhibitor Screening Assay
Anwendung: HTS, drug discovery, enzyme assays
ab 1.002,00 €
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Transcreener(R) cGAMP cGAS TR-FRET Assay
Transcreener(R) cGAMP cGAS TR-FRET Assay

Artikelnummer: BBL-3025-10K

The Transcreener(R) cGAMP cGAS TR-FRET Assay is a far-red, competitive fluorescence polarization (FP) assay. The Transcreener(R) assay is designed specifically for high throughput screening (HTS), with a single addition, mix-and-read format. Because the antibody is highly selective for cGAMP, the assay can be used...
Schlagworte: cGAS Activity Assay, cGAS Inhibitor Screening Assay
Anwendung: HTS, drug discovery, enzyme assays
ab 1.100,00 €
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Transcreener(R) ADO CD73 FP Assay
Transcreener(R) ADO CD73 FP Assay

Artikelnummer: BBL-3026-10K

The Transcreener(R) CD73 FP Assay is a far-red, competitive fluorescence polarization (FP) assay. The assay is designed to be used with enzymes such as ecto-5'-nucleotidase (also known as 5'-nucleotidase, NT5E, Cluster of Diferentiation 73, or CD73), that produce the product adenosine (ADO) The Transcreener CD73 FP...
Schlagworte: CD73 Activity Assay, CD73 Inhibitor Screening Assay
Anwendung: HTS, drug discovery, enzyme assays
ab 1.134,00 €
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Transcreener(R) dAMP FP Assay
Transcreener(R) dAMP FP Assay

Artikelnummer: BBL-3028-10K

The Transcreener(R) dAMP FP Assay is a far-red, competitive fluorescence polarization (FP) assay. The assay is designed to be used with exonuclease enzymes such as TREX1 (also known as Three Prime Repair Exonuclease 1), that produce the product dAMP (deoxyadenosine monophosphate, deoxyadenylic acid, or...
Schlagworte: Exonuclease Activity Assay, Exonuclease Inhibitor Screening Assay
Anwendung: HTS, drug discovery, enzyme assays
Spezies-Reaktivität: human
ab 827,00 €
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Transcreener(R) ADPR FP Assay
Transcreener(R) ADPR FP Assay

Artikelnummer: BBL-3030-10K

The Transcreener(R) ADPR FP Assay is a biochemical HTS assay for measuring the production of ADP-ribose (ADPR) in enzymatic reactions. The assay uses a coupling enzyme to convert ADPR into AMP, which is then detected using a far-red, competitive fluorescence polarization (FP) assay. As examples, the Transcreener...
Schlagworte: CD38 Activity Assay, CD38 Inhibitor Screening Assay, PARG Activity Assay, PARG Inhibitor Screening Assay, SARM1 Activity...
Anwendung: HTS, drug discovery, enzyme assays
Spezies-Reaktivität: human
ab 1.025,00 €
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Enzolution(R) CD38 Assay System
Enzolution(R) CD38 Assay System

Artikelnummer: BBL-3031-10K

The Enzolution(R) CD38 Assay System is intended for use with the Transcreener(R) ADPR FP Assay Kit (Part #3031) to measure enzymatic activity for CD38 (Also known as Cluster of Differentiation 38). CD38 is a multifunctional, membrane-bound enzyme that modulates beta-Nicotinamide adenine dinucleotide (NAD) levels by...
Schlagworte: T10, CD38, ADP-ribosyl cyclase 1, Cyclic ADP-ribose hydrolase 1, 2'-phospho-ADP-ribosyl cyclase,...
Anwendung: HTS, drug discovery, enzyme assays
ab 626,00 €
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Enzolution(R) WRN Helicase FI Assay System
Enzolution(R) WRN Helicase FI Assay System

Artikelnummer: BBL-3032-10K-FI

The Enzolution(R) WRN Helicase Assay System is intended for use with the Transcreener(R) ADP2 Assay Kits to measure enzymatic activity for WRN Helicase (Also known as Werner Syndrome ATP-dependent Helicase). WRN is a multifunctional enzyme that has both magnesium and ATP-dependent DNA-helicase activity and 3'->5'...
Schlagworte: WRN, RecQ protein-like 2, Werner syndrome protein, DNA helicase, RecQ-like type 3, Bifunctional 3'-5'...
Anwendung: HTS, drug discovery, enzyme assays
ab 626,00 €
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Enzolution(R) WRN Helicase FP Assay System
Enzolution(R) WRN Helicase FP Assay System

Artikelnummer: BBL-3032-10K-FP

The Enzolution(R) WRN Helicase Assay System is intended for use with the Transcreener(R) ADP2 Assay Kits to measure enzymatic activity for WRN Helicase (Also known as Werner Syndrome ATP-dependent Helicase). WRN is a multifunctional enzyme that has both magnesium and ATP-dependent DNA-helicase activity and 3'->5'...
Schlagworte: WRN, RecQ protein-like 2, Werner syndrome protein, DNA helicase, RecQ-like type 3, Bifunctional 3'-5'...
Anwendung: HTS, drug discovery, enzyme assays
ab 865,00 €
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Enzolution(R) WRN Helicase TR-FRET Assay System
Enzolution(R) WRN Helicase TR-FRET Assay System

Artikelnummer: BBL-3032-10K-TR

The Enzolution(R) WRN Helicase Assay System is intended for use with the Transcreener(R) ADP2 Assay Kits to measure enzymatic activity for WRN Helicase (Also known as Werner Syndrome ATP-dependent Helicase). WRN is a multifunctional enzyme that has both magnesium and ATP-dependent DNA-helicase activity and 3'->5'...
Schlagworte: WRN, RecQ protein-like 2, Werner syndrome protein, DNA helicase, RecQ-like type 3, Bifunctional 3'-5'...
Anwendung: HTS, drug discovery, enzyme assays
ab 626,00 €
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Enzolution(R) POLQ ATPase FI Assay System
Enzolution(R) POLQ ATPase FI Assay System

Artikelnummer: BBL-3034-10K-FI

The Enzolution(R) POLQ Helicase ATPase Assay System is intended for use with the Transcreener(R) ADP2 Assay Kits to measure the DNA-dependent ATPase activity of the POLQ Helicase domain. POLQ (also known as DNA Polymerase Theta), is a multifunctional enzyme with template-dependent DNA polymerase, ATPdependent...
Schlagworte: POLQ, DNA polymerase eta, DNA polymerase theta
Anwendung: HTS, drug discovery, enzyme assays
ab 626,00 €
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Enzolution(R) RIG-I ATPase FI Assay System
Enzolution(R) RIG-I ATPase FI Assay System

Artikelnummer: BBL-3035-10K-FI

The Enzolution(R) RIG-I ATPase Assay System is intended for use with the Transcreener(R) ADP2 Assay Kits to measure the RNA-dependent ATPase activity of RIG-I. RIG-I (retinoic acid-inducible gene I), is a cytosolic pattern recognition receptor (PRR) that induces type-I interferon (IFN1) in response to dsRNA. ADP...
Schlagworte: RIGI, RNA sensor RIG-I, DEAD box protein 58, RIG-I-like receptor 1, ATP-dependent RNA helicase DDX58, Retinoic...
Anwendung: HTS, drug discovery, enzyme assays
ab 827,00 €
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Enzolution(R) RIG-I ATPase FP Assay System
Enzolution(R) RIG-I ATPase FP Assay System

Artikelnummer: BBL-3035-10K-FP

The Enzolution(R) RIG-I ATPase Assay System is intended for use with the Transcreener(R) ADP2 Assay Kits to measure the RNA-dependent ATPase activity of RIG-I. RIG-I (retinoic acid-inducible gene I), is a cytosolic pattern recognition receptor (PRR) that induces type-I interferon (IFN1) in response to dsRNA. ADP...
Schlagworte: RIGI, RNA sensor RIG-I, DEAD box protein 58, RIG-I-like receptor 1, ATP-dependent RNA helicase DDX58, Retinoic...
Anwendung: HTS, drug discovery, enzyme assays
ab 827,00 €
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