Produkte von BellBrook Labs
BellBrook Labs ist ein führender Anbieter von biochemischen Assay-Lösungen für die Wirkstoffforschung und Enzymanalyse. Das Unternehmen entwickelt und vertreibt innovative High-Throughput-Screening-(HTS)-Assays, validierte Enzyme sowie passende Reagenzien und unterstützt Kunden zusätzlich mit Assayentwicklung, Workflow-Validierung und wissenschaftlichen Dienstleistungen. Mit den proprietären Plattformen Transcreener® und AptaFluor® ermöglicht BellBrook Labs sensitive, robuste und anwenderfreundliche Messverfahren für ein breites Spektrum enzymatischer Targets in Pharma-, Biotech- und akademischen Forschungseinrichtungen.
Mehr Informationen unter: www.bellbrooklabs.com
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NEU
Recombinant IRE1a, Active, Human
Artikelnummer: BBL-2373
Recombinant human IRE1a (amino acids 547-977), N-terminal 6xHis tag, 50.47 kDa, expressed and purified from baculovirus-infected insect cells. The enzyme has been thoroughly validated with the Transcreener ADP2 Kinase Assay Kits. For specific activity, please refer to the Certificate of Analysis for each individual...
| Schlagworte: | ERN1, Ire1-alpha, Inositol-requiring protein 1, Endoplasmic reticulum-to-nucleus signaling 1, Serine/threonine-protein... |
| Anwendung: | HTS, drug discovery, enzyme assays |
| Exprimiert in: | Insect cells |
| Ursprungsart: | human |
ab 443,00 €
NEU
Recombinant eIF4A1 Enzyme, Active, Human
Artikelnummer: BBL-2383
Active, human, full-length eIF4A1 protein expressed and purified from E.coli. The enzyme has been thoroughly validated with the Transcreener ADP Assay Kit. For specific activity, please refer to the Certificate of Analysis for each individual enzyme lot. Purity is >90% in a composition of 50 mM Tris-HCl, 500 mM...
| Schlagworte: | EIF4A1, Eukaryotic initiation factor 4A-I, ATP-dependent RNA helicase eIF4A-1 |
| Anwendung: | HTS, drug discovery, enzyme assays |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
454,00 €
NEU
Recombinant eIF4A3 Enzyme, Active, Human
Artikelnummer: BBL-2385
Active, human, full-length eIF4A3 protein expressed and purified from E.coli. The enzyme has been thoroughly validated with the Transcreener ADP Assay Kit. For specific activity, please refer to the Certificate of Analysis for each individual enzyme lot. Purity is >85% in a composition of 50 mM Tris-HCl, 150 mM...
| Schlagworte: | EIF4A3, DEAD box protein 48, Nuclear matrix protein 265, ATP-dependent RNA helicase DDX48, ATP-dependent RNA helicase... |
| Anwendung: | HTS, drug discovery, enzyme assays |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
557,00 €
NEU
Transcreener(R) ADP2 FP Assay
Artikelnummer: BBL-3010-10K
The Transcreener(R) HTS Assay platform overcomes the need for time-consuming, one-off assay development for individual members within a group transfer enzyme family by utilizing a single set of assay reagents that detect an invariant product. The generic nature of the Transcreener HTS Assay platform eliminates...
| Schlagworte: | Kinase Activity Assay, Kinase Inhibitor Screening Assay, ATPase Activity Assay, ATPase Inhibitor Screening Assay |
| Anwendung: | HTS, drug discovery, enzyme assays |
ab 865,00 €
NEU
Transcreener(R) ADP2 FI Assay
Artikelnummer: BBL-3013-10K
The Transcreener(R) HTS Assay platform overcomes the need for time-consuming, one-off assay development for individual members within a group transfer enzyme family by utilizing a single set of assay reagents that detect an invariant product. The generic nature of the Transcreener HTS Assay platform eliminates...
| Schlagworte: | Kinase Activity Assay, Kinase Inhibitor Screening Assay, ATPase Activity Assay, ATPase Inhibitor Screening Assay |
| Anwendung: | HTS, drug discovery, enzyme assays |
ab 432,00 €
NEU
Transcreener(R) GDP FI Assay
Artikelnummer: BBL-3014-10K
The Transcreener(R) GDP FI Assay is a competitive immunoassay for GDP with a red fluorescent intensity (FI) readout. Designed specifically for HTS and featuring a single addition mix-and-read format and room temperature reagent stability, the Transcreener GDP FI Assay is compatible with plate readers typically found...
| Schlagworte: | GTPase Activity Assay, GTPase Inhibitor Screening Assay |
| Anwendung: | HTS, drug discovery, enzyme assays |
ab 432,00 €
NEU
Transcreener(R) AMP2/GMP2 FP Assay
Artikelnummer: BBL-3015-10K
The Transcreener(R)AMP2/GMP2 FP Assay is a universal biochemical HTS assay for enzymes that produce AMP or GMP, including ubiquitin, SUMO, nucleic acid and protein ligases, phosphodiesterases (PDEs), and synthetases. Enzyme activity is signaled by a decrease in fluorescence polarization as the bound tracer is...
| Schlagworte: | Phosphodiesterase Activity Assay, PDE Inhibitor Screening Assay |
| Anwendung: | HTS, drug discovery, enzyme assays |
ab 865,00 €
NEU
Transcreener(R) EPIGEN SAH Methyltransferase Assay
Artikelnummer: BBL-3017-10K
The Transcreener(R) EPIGEN Methyltransferase Assay is a universal biochemical HTS assay for enzymes that produce S-adenosylhomocysteine (SAH), including all enzymes within the histone (HMTs) and DNA (DNMTs) methyltransferase families. It combines the extensively validated Transcreener AMP2/GMP2 Assay, which relies...
| Schlagworte: | Methyltransferase Activity Assay, Methyltransferase Inhibitor Screening Assay |
| Anwendung: | HTS, drug discovery, enzyme assays |
ab 1.230,00 €
NEU
Transcreener(R) UDP2 FI Assay
Artikelnummer: BBL-3019-10K
The Transcreener(R) UDP2 FI Assay is a universal biochemical HTS assay for enzymes that produce UDP, including glycosyltransferase, galactosyltransferase, glucuronyltransferase, N-acetylglucosamyltransferase, N-acetlygalactosyltransferase, xylosyltransferase, and glycogen, cellulose, lactose and hyaluronan...
| Schlagworte: | Glycosyltransferase Activity Assay, Glycosyltransferase Inhibitor Screening Assay |
| Anwendung: | HTS, drug discovery, enzyme assays |
ab 432,00 €
NEU
Transcreener(R) GDP TR-FRET Assay
Artikelnummer: BBL-3021-10K
The Transcreener(R) GDP TR-FRET Red Assay is a competitive immunoassay for GDP with a far-red, time-resolved Förster-resonance-energy-transfer (TR-FRET) readout. Because it is highly selective for GDP, the assay can be used with any enzyme that converts GTP to GDP, regardless of what other substrates are used....
| Schlagworte: | GTPase Activity Assay, GTPase Inhibitor Screening Assay |
| Anwendung: | HTS, drug discovery, enzyme assays |
ab 774,00 €
NEU
Transcreener(R) UDP2 TR-FRET Assay
Artikelnummer: BBL-3022-10K
The Transcreener(R) UDP2 TR-FRET Red Assay is a competitive immunoassay for UDP with a far-red, time-resolved Förster-resonance-energy-transfer (TR-FRET) readout. Because it is highly selective for UDP, the assay can be used with any enzyme that generates UDP from a UDP-sugar donor. Examples include...
| Schlagworte: | Glycosyltransferase Activity Assay, Glycosyltransferase Inhibitor Screening Assay |
| Anwendung: | HTS, drug discovery, enzyme assays |
ab 945,00 €
NEU
AptaFluor(R) SAH Methyltransferase Assay
Artikelnummer: BBL-3023-10K
The AptaFluor(R) SAH Methyltransferase TR-FRET Assay is a universal assay for enzymes that convert S-adenosylmethionine (SAM) to S-adenosylhomocysteine (SAH), with a far-red, time-resolved Förster-resonance-energy-transfer (TR-FRET) readout. The assay can be used for all enzymes within the histone methyltransferase...
| Schlagworte: | Methyltransferase Activity Assay, Methyltransferase Inhibitor Screening Assay |
| Anwendung: | HTS, drug discovery, enzyme assays |
ab 478,00 €