Produkte von BellBrook Labs
BellBrook Labs ist ein führender Anbieter von biochemischen Assay-Lösungen für die Wirkstoffforschung und Enzymanalyse. Das Unternehmen entwickelt und vertreibt innovative High-Throughput-Screening-(HTS)-Assays, validierte Enzyme sowie passende Reagenzien und unterstützt Kunden zusätzlich mit Assayentwicklung, Workflow-Validierung und wissenschaftlichen Dienstleistungen. Mit den proprietären Plattformen Transcreener® und AptaFluor® ermöglicht BellBrook Labs sensitive, robuste und anwenderfreundliche Messverfahren für ein breites Spektrum enzymatischer Targets in Pharma-, Biotech- und akademischen Forschungseinrichtungen.
Mehr Informationen unter: www.bellbrooklabs.com
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NEU
Enzolution(R) MDA5 ATPase FI Assay System
Artikelnummer: BBL-3036-10K-FI
The Enzolution(R) MDA5 ATPase Assay System is intended for use with the Transcreener(R) ADP2 Assay Kits to measure the RNA-dependent ATPase activity of MDA5. MDA5 (melanoma differentiation-associated gene 5) is a member of the RLR (RIG-I-like receptors) family of immune sensors that bind double-stranded RNA (dsRNA)...
| Schlagworte: | IFIH1, RIG-I-like receptor 2, Helicase with 2 CARD domains, Murabutide down-regulated protein, RNA helicase-DEAD box... |
| Anwendung: | HTS, drug discovery, enzyme assays |
ab 910,00 €
NEU
Enzolution(R) MDA5 ATPase TR-FRET Assay System
Artikelnummer: BBL-3036-10K-TR
The Enzolution(R) MDA5 ATPase Assay System is intended for use with the Transcreener(R) ADP2 Assay Kits to measure the RNA-dependent ATPase activity of MDA5. MDA5 (melanoma differentiation-associated gene 5) is a member of the RLR (RIG-I-like receptors) family of immune sensors that bind double-stranded RNA (dsRNA)...
| Schlagworte: | IFIH1, RIG-I-like receptor 2, Helicase with 2 CARD domains, Murabutide down-regulated protein, RNA helicase-DEAD box... |
| Anwendung: | HTS, drug discovery, enzyme assays |
ab 910,00 €
NEU
Enzolution(R) DDX5 ATPase TR-FRET Assay System
Artikelnummer: BBL-3039-10K-TR
The Enzolution(R) DDX5 Assay System is intended for use with the Transcreener(R) ADP2 Assay Kits to measure the ATP-dependent RNA helicase activity of DDX5. DDX5, also known as p68, is a DEAD Box helicase protein characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), that catalyzes ATPdependent unwinding of...
| Schlagworte: | DDX5, RNA helicase p68, DEAD box protein 5, Probable ATP-dependent RNA helicase DDX5 |
| Anwendung: | HTS, drug discovery, enzyme assays |
ab 1.207,00 €
NEU
Enzolution(R) DDX41 ATPase FI Assay System
Artikelnummer: BBL-3041-10K-FI
The Enzolution(R) DDX41 Assay System is intended for use with the Transcreener(R) ADP2 Assay Kits to measure the ATP-dependent RNA helicase activity of DDX41. DDX41, a DEAD box protein, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), is an ATP-dependent helicase that unwinds dsRNA and dsDNA. ADP...
| Schlagworte: | DDX41, DEAD box protein 41, DEAD box protein abstrakt homolog, Probable ATP-dependent RNA helicase DDX41 |
| Anwendung: | HTS, drug discovery, enzyme assays |
ab 1.549,00 €
NEU
Enzolution(R) DHX9 ATPase FI Assay System
Artikelnummer: BBL-3042-10K-FI
The Enzolution(R) DHX9 ATPase Assay System is intended for use with the Transcreener(R) ADP2 Assay Kits to measure the ATP-dependent RNA helicase activity of DHX9, a member of the a DExH/D helicase family. Though it is classified as an RNA helicase, DHX9 also has been reported to unwind DNA and DNA:RNA hybrids. ADP...
| Schlagworte: | DHX9 Assay, DHX9 inhibitor screening kit |
| Anwendung: | HTS, drug discovery, enzyme assays |
ab 637,00 €
NEU
Enzolution(R) DHX9 ATPase FP Assay System
Artikelnummer: BBL-3042-10K-FP
The Enzolution(R) DHX9 ATPase Assay System is intended for use with the Transcreener(R) ADP2 Assay Kits to measure the ATP-dependent RNA helicase activity of DHX9, a member of the a DExH/D helicase family. Though it is classified as an RNA helicase, DHX9 also has been reported to unwind DNA and DNA:RNA hybrids. ADP...
| Schlagworte: | DHX9 Assay, DHX9 inhibitor screening kit |
| Anwendung: | HTS, drug discovery, enzyme assays |
ab 637,00 €
NEU
Transcreener(R) pADPr PARP TR-FRET Assay
Artikelnummer: BBL-3044-10K
The Transcreener(R) pADPr PARP TR-FRET Assay is a biochemical HTS assay for measuring the production of poly(ADP-ribose) (pADPr) in poly(ADP-ribose) polymerase (PARP) reactions. The assay relies on pADPr Coupling Enzymes (CE) to convert pADPr into AMP, which is then detected using a far-red, timeresolved...
| Schlagworte: | PARP Activity Assay, PARP Inhibitor Screening Assay |
| Anwendung: | HTS, drug discovery, enzyme assays |
| Spezies-Reaktivität: | human |
ab 1.310,00 €
NEU
Heliscreener(TM) RNA Helicase Unwinding Assay
Artikelnummer: BBL-3051-10K
The Heliscreener RNA Unwinding Assay is a biochemical assay designed to measure the RNA unwinding activity of RNA helicases in the DExH/D-box family. The assay utilizes a labeled double-stranded RNA (dsRNA) substrate that is quenched when intact and emits far-red fluorescence following unwinding. The assay can be...
| Schlagworte: | RNA Helicase Unwinding Assay, RNA Unwinding Assay |
| Anwendung: | HTS, drug discovery, enzyme assays |
ab 911,00 €
NEU
Enzolution(R) eIF4A1 ATPase FP Assay System
Artikelnummer: BBL-3055-10K-FP
The Enzolution EIF4A1 ATPase Assay System is intended for use with the Transcreener(R) ADP Assay Kits to measure the RNA-dependent ATPase activity of EIF4A1 (eukaryotic initiation factor 4A-I), a member of the DEAD-box family of RNA helicase family (DDX2A). EIF4A1 functions as a core component of the EIF4F...
| Schlagworte: | EIF4A1, Eukaryotic initiation factor 4A-I, ATP-dependent RNA helicase eIF4A-1 |
| Anwendung: | HTS, drug discovery, enzyme assays |
| Spezies-Reaktivität: | human |
ab 899,00 €
NEU
Enzolution(R) eIF4A1 ATPase TR-FRET Assay System
Artikelnummer: BBL-3055-10K-TR
The Enzolution EIF4A1 ATPase Assay System is intended for use with the Transcreener(R) ADP Assay Kits to measure the RNA-dependent ATPase activity of EIF4A1 (eukaryotic initiation factor 4A-I), a member of the DEAD-box family of RNA helicase family (DDX2A). EIF4A1 functions as a core component of the EIF4F...
| Schlagworte: | EIF4A1, Eukaryotic initiation factor 4A-I, ATP-dependent RNA helicase eIF4A-1 |
| Anwendung: | HTS, drug discovery, enzyme assays |
| Spezies-Reaktivität: | human |
ab 922,00 €
NEU
Heliscreener(TM) WRN Helicase Unwinding Assay
Artikelnummer: BBL-5054-10K
The Heliscreener WRN Helicase DNA Unwinding Assay is a biochemical assay designed to measure the DNA unwinding activity of BLM helicase (BLM-H). The assay utilizes a labeled double-stranded DNA substrate that is quenched when intact and emits far-red fluorescence following unwinding. The assay can be performed in...
| Schlagworte: | WRN, RecQ protein-like 2, Werner syndrome protein, DNA helicase, RecQ-like type 3, Bifunctional 3'-5'... |
| Anwendung: | HTS, drug discovery, enzyme assays |
ab 854,00 €
NEU
Recombinant cGAS Enzyme, Active, Human, Full-Length
Artikelnummer: BBL-2227
Active, full-length Human Cyclic GMP-AMP synthase enzyme, His-tagged protein expressed and purified from E.coli. The enzyme has been thoroughly validated with Transcreener cGAS Activity Assays. For specific activity, please refer to the Certificate of Analysis for each individual enzyme lot. Purity is >90% in a 20mM...
| Schlagworte: | CGAS, 2'3'-cGAMP synthase, Cyclic GMP-AMP synthase, Mab-21 domain-containing protein 1 |
| Anwendung: | HTS, drug discovery, enzyme assays |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
ab 500,00 €