Produkte von BellBrook Labs

BellBrook Labs

BellBrook Labs ist ein führender Anbieter von biochemischen Assay-Lösungen für die Wirkstoffforschung und Enzymanalyse. Das Unternehmen entwickelt und vertreibt innovative High-Throughput-Screening-(HTS)-Assays, validierte Enzyme sowie passende Reagenzien und unterstützt Kunden zusätzlich mit Assayentwicklung, Workflow-Validierung und wissenschaftlichen Dienstleistungen. Mit den proprietären Plattformen Transcreener® und AptaFluor® ermöglicht BellBrook Labs sensitive, robuste und anwenderfreundliche Messverfahren für ein breites Spektrum enzymatischer Targets in Pharma-, Biotech- und akademischen Forschungseinrichtungen.

Mehr Informationen unter: www.bellbrooklabs.com

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Recombinant SIRT3 Enzyme, Active, Human
Recombinant SIRT3 Enzyme, Active, Human

Artikelnummer: BBL-2367

Active, human SIRT3 (AA 101-399) protein expressed and purified from E.Coli with an N-Terminal His tag. The enzyme has been thoroughly validated with the Transcreener OAADPr Assay Kit. For specific activity, please refer to the Certificate of Analysis for each individual enzyme lot. Purity is 95% in a composition of...
Schlagworte: SIRT3, SIR2-like protein 3, Regulatory protein SIR2 homolog 3, NAD-dependent protein delactylase sirtuin-3, NAD-dependent...
Anwendung: HTS, drug discovery, enzyme assays
Exprimiert in: E.coli
Ursprungsart: human
ab 454,00 €
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NEU
Recombinant VPS4B, Active, Human
Recombinant VPS4B, Active, Human

Artikelnummer: BBL-2371

Active, human VPS4B (AA 1-444) full-length protein expressed and purified from E.Coli. The enzyme has been thoroughly validated with the Transcreener ADP Assay Kit. For specific activity, please refer to the Certificate of Analysis for each individual enzyme lot. Purity is 95% in a composition of 50 mM Tris-HCl, 500...
Schlagworte: VPS4B, Cell migration-inducing gene 1 protein, Suppressor of K(+) transport growth defect 1, Vacuolar protein...
Anwendung: HTS, drug discovery, enzyme assays
Exprimiert in: E.coli
Ursprungsart: human
ab 557,00 €
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NEU
Recombinant APE2 Enzyme, Active, Human
Recombinant APE2 Enzyme, Active, Human

Artikelnummer: BBL-2381

Active, human APE2 enzyme, full-length, His-tagged protein expressed and purified from baculovirus-infected insect cells. The enzyme has been thoroughly validated with the Transcreener dAMP Assay Kit. For specific activity, please refer to the Certificate of Analysis for each individual enzyme lot. Purity is >70% in...
Schlagworte: APEX2, APEX nuclease 2, AP endonuclease XTH2, APEX nuclease-like 2, Apurinic-apyrimidinic endonuclease 2, DNA-(apurinic or...
Anwendung: HTS, drug discovery, enzyme assays
Exprimiert in: Insect cells
Ursprungsart: human
ab 671,00 €
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NEU
Transcreener(R) GDP FP Assay
Transcreener(R) GDP FP Assay

Artikelnummer: BBL-3009-10K

The Transcreener(R) HTS Assay platform overcomes the need for time-consuming, one-off assay development for individual members within a group transfer enzyme family by utilizing a single set of assay reagents that detect an invariant product. The generic nature of the Transcreener HTS Assay platform eliminates...
Schlagworte: GTPase Activity Assay, GTPase Screening Assay
Anwendung: HTS, drug discovery, enzyme assays
ab 671,00 €
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NEU
Transcreener(R) ADP2 TR-FRET Assay
Transcreener(R) ADP2 TR-FRET Assay

Artikelnummer: BBL-3011-10K

The Transcreener(R) ADP2 TR-FRET Red Assay is a competitive immunoassay for ADP with a far-red, time-resolved Förster-resonance-energy-transfer (TR-FRET) readout. Because it is highly selective for ADP, the assay can be used with any enzyme that converts ATP to ADP, regardless of what other substrates are used....
Schlagworte: Kinase Activity Assay, Kinase Inhibitor Screening Assay, ATPase Activity Assay, ATPase Inhibitor Screening Assay
Anwendung: HTS, drug discovery, enzyme assays
ab 945,00 €
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NEU
Transcreener(R) UDP2 FP Assay
Transcreener(R) UDP2 FP Assay

Artikelnummer: BBL-3018-10K

The Transcreener(R) UDP2 FP Assay is a universal biochemical HTS assay for enzymes that produce UDP, including glycosyltransferase, galactosyltransferase, glucuronyltransferase, N-acetylglucosamyltransferase, N-acetlygalactosyltransferase, xylosyltransferase, and glycogen, cellulose, lactose and hyaluronan...
Schlagworte: Glycosyltransferase Activity Assay, Glycosyltransferase Inhibitor Screening Assay
Anwendung: HTS, drug discovery, enzyme assays
ab 865,00 €
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NEU
Transcreener(R) AMP2/GMP2 TR-FRET Assay
Transcreener(R) AMP2/GMP2 TR-FRET Assay

Artikelnummer: BBL-3020-10K

The Transcreener(R) AMP2/GMP2 TR-FRET Red Assay is a competitive immunoassay for enzymes that produce AMP or GMP with a far-red, time-resolved Förster-resonance-energy-transfer (TR-FRET) readout. The assay relies on a highly specific monoclonal antibody that recognizes AMP or GMP with more than 1,000-fold...
Schlagworte: Phosphodiesterase Activity Assay, PDE Inhibitor Screening Assay
Anwendung: HTS, drug discovery, enzyme assays
ab 945,00 €
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NEU
Transcreener(R) 2-5A OAS FP Activity Assay
Transcreener(R) 2-5A OAS FP Activity Assay

Artikelnummer: BBL-3027-10K

The Transcreener(R) OAS FP Assay is a far-red, competitive fluorescence polarization (FP) assay. The assay is designed to be used with the 2'-5'-oligoadenylate synthase (OAS) family of enzymes, such as OAS1, OAS2, and OAS3), that produce the product 2-5A. The Transcreener OAS FP Assay is a simple biochemical assay...
Schlagworte: OAS Activity Assay, OAS Inhibitor Screening Assay
Anwendung: HTS, drug discovery, enzyme assays
ab 1.134,00 €
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NEU
Enzolution(R) TREX1 Assay System
Enzolution(R) TREX1 Assay System

Artikelnummer: BBL-3029-10K

The Enzolution(R) TREX1 Assay System is intended for use with the Transcreener(R) dAMP FP Assay Kit (Part #3028) to measure enzymatic activity for TREX1 (also known as Three Prime Repair Exonuclease 1). TREX1 is the major exonuclease responsible for degrading cytosolic DNA, and it plays an important role in...
Schlagworte: TREX1, Deoxyribonuclease III, 3'-5' exonuclease TREX1, Three-prime repair exonuclease 1
Anwendung: HTS, drug discovery, enzyme assays
ab 626,00 €
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NEU
Enzolution(R) PARG Assay System
Enzolution(R) PARG Assay System

Artikelnummer: BBL-3033-10K

The Enzolution(R) PARG Assay System is intended for use with the Transcreener(R) ADPR FP Assay Kit (Part #3030) to measure enzymatic activity for PARG (poly(ADP-ribose) glycohydrolase). PARG produces ADPR from the breakdown of poly(ADP-ribose) (polyADPR). It plays an important role in DNA damage repair and has been...
Schlagworte: PARG, Poly(ADP-ribose) glycohydrolase
Anwendung: HTS, drug discovery, enzyme assays
ab 1.127,00 €
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NEU
Enzolution(R) POLQ ATPase FP Assay System
Enzolution(R) POLQ ATPase FP Assay System

Artikelnummer: BBL-3034-10K-FP

The Enzolution(R) POLQ Helicase ATPase Assay System is intended for use with the Transcreener(R) ADP2 Assay Kits to measure the DNA-dependent ATPase activity of the POLQ Helicase domain. POLQ (also known as DNA Polymerase Theta), is a multifunctional enzyme with template-dependent DNA polymerase, ATPdependent...
Schlagworte: POLQ, DNA polymerase eta, DNA polymerase theta
Anwendung: HTS, drug discovery, enzyme assays
ab 626,00 €
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NEU
Enzolution(R) POLQ ATPase TR-FRET Assay System
Enzolution(R) POLQ ATPase TR-FRET Assay System

Artikelnummer: BBL-3034-10K-TR

The Enzolution(R) POLQ Helicase ATPase Assay System is intended for use with the Transcreener(R) ADP2 Assay Kits to measure the DNA-dependent ATPase activity of the POLQ Helicase domain. POLQ (also known as DNA Polymerase Theta), is a multifunctional enzyme with template-dependent DNA polymerase, ATPdependent...
Schlagworte: POLQ, DNA polymerase eta, DNA polymerase theta
Anwendung: HTS, drug discovery, enzyme assays
ab 626,00 €
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