Products from TargetMol
TargetMol, based in Boston, Massachusetts, was founded in 2015 and is a drug screening expert in the life science community. The company offers diverse compound libraries, including FDA-approved libraries, and covers a broad spectrum of small molecule compounds such as inhibitors and agonists as well as recombinant proteins and natural products. TargetMol's products are used by researchers worldwide in areas such as cancer research, neurobiology, inflammation, immunology and metabolism.
More information at: www.targetmol.com
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2-Ketoglutaric acid Sodium
Item number: TGM-T4920-200mg
Description: 2-Ketoglutaric acid Sodium (AKG) is a key molecule in the TCA cycle. It can be produced from glutamate by oxidative deamination via glutamate dehydrogenase and as a product of pyridoxal phosphate-dependent transamination reactions (mediated by branched-chain amino acid transaminases) in which glutamate...
| Keywords: | alpha-Ketoglutaric acid sodium salt , 2-oxoglutarate monobasic , Oxoglutaric acid , AKG |
| MW: | 168.08 D |
From 30.00€
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Dihydroxyfumaric acid hydrate
Item number: TGM-T4931-100mg
Description: Dihydroxyfumaric acid is a known generator of superoxide anions and by hydroxyl free radicals. Dihydroxyfumarate exposure can cause insulin inhibitory effects. It can spontaneously convert to hydroxypyruvate or to oxaloglycolate. Target: Endogenous Metabolite. Smiles: O.OC(=O)C(\O)=C(/O)C(O)=O
| MW: | 166.09 D |
From 20.00€
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steviolbioside
Item number: TGM-T4964-100mg
Description: Steviolbioside (CCRIS-6025) is a natural sweetener, it presents notable inhibition on human hepatocarcinoma cell Hep3B, human breast cancer cell MDA-MB-231 and human pancreatic cancer cell BxPC-3, thus, steviolbioside(CCRIS-6025) could be a potential remedy for human breast cancer. Steviolbioside...
| Keywords: | CCRIS-6025 |
| MW: | 642.73 D |
From 30.00€
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Sofalcone
Item number: TGM-T4977-50mg
Description: Sofalcone (SU-88), a gastric antiulcer agent in clinical use, is known to induce the expression of Heme oxygenase-1 (HO-1) in gastric epithelium. Target: Antibacterial, Autophagy. Smiles: O(CC(O)=O)C1=C(C(C=CC2=CC=C(OCC=C(C)C)C=C2)=O)C=CC(OCC=C(C)C)=C1. References: Onda K, et al. Sofalcone upregulates...
| Keywords: | SU-88 |
| MW: | 450.52 D |
34.00€
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Linoleic acid
Item number: TGM-T4P2931-10g
Description: Linoleic acid (9,12-octadecadienoic acid) is a naturally occurring polyunsaturated fatty acid found in animal and vegetable oils. Linoleic acid is an essential fatty acid that is part of membrane phospholipids. Target: Endogenous Metabolite. Smiles: C(C/C=C\C/C=C\CCCCC)CCCCCC(O)=O. References: Belal SA,...
| Keywords: | 9,12-octadecadienoic acid , acidelinoleique , 9,12-Linoleic acid |
| MW: | 280.45 D |
From 32.00€
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Toddalolactone
Item number: TGM-T4S0592-100mg
Description: Toddalolactone ((+)-Toddalolactone) is an anti-inflammatory and analgesic. Target: PAI-1. Smiles: COc1cc2oc(=O)ccc2c(OC)c1C[C@@H](O)C(C)(C)O. References: Bo Y , Guangping Z , Lingling J , et al. Inhibition of PAI-1 Activity by Toddalolactone as a Mechanism for Promoting Blood Circulation and Removing...
| Keywords: | (+)-Toddalolactone |
| MW: | 308.33 D |
From 32.00€
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Tubeimoside III
Item number: TGM-T4S1849-100mg
Description: Tubeimoside III has anti-inflammatory, anti-tumor, and anti-tumorigenic activities, stronger than those of tubeimoside II. Target: Others. Smiles:...
| MW: | 1365.46 D |
From 35.00€
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10-Deacetyltaxol
Item number: TGM-T5165-100mg
Description: 10-Deacetyltaxol (10-DAT) is extracted from Taxus brevifolia barks. Target: Microtubule Associated. Smiles: CC(=O)O[C@@]12CO[C@@H]1C[C@H](O)[C@]1(C)[C@@H]2[C@H](OC(=O)c2ccccc2)[C@]2(O)C[C@H](OC(=O)[C@H](O)[C@@H](NC(=O)c3ccccc3)c3ccccc3)C(C)=C([C@@H](O)C1=O)C2(C)C. References: Grobosch T, et al. J Anal...
| Keywords: | Deacetyltaxol , 10-deacetyl-paclitaxel , Deacetyl Paclitaxel , 10-Desacetyl Paclitaxel , 10-DAT |
| MW: | 811.87 D |
From 31.00€
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Indirubin-3'-monoxime
Item number: TGM-T5200-200mg
Description: Indirubin-3'-monoxime (Indirubin-3'-oxime) is a potent inhibitor of GSK3beta (IC50: 22 nM) and also inhibits CDKs ( (IC50s: 100/180/250 nM for Cdk5/p35, Cdk1/cyclin B, Cdk2/cyclin E). Target: Lipoxygenase, GSK-3, CDK. Smiles: ON=C1C(Nc2ccccc12)=C1C(=O)Nc2ccccc12. References: Leclerc S, et al....
| Keywords: | Indirubin-3'-oxime |
| MW: | 277.28 D |
From 31.00€
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Glycoursodeoxycholic acid
Item number: TGM-T5234-100mg
Description: Glycoursodeoxycholic acid (Ursodeoxycholylglycine) is an acyl glycine and a bile acid-glycine conjugate. It is a secondary bile acid produced by the action of enzymes existing in the microbial flora of the colonic environment. In hepatocytes, both primary and secondary bile acids undergo amino acid...
| Keywords: | Ursodeoxycholylglycine , GUDCA |
| MW: | 449.62 D |
From 30.00€
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CFTR corrector 2
Item number: TGM-T5312-200mg
Description: CFTR corrector 2 (FDL169) is a novel and potent CFTR (Cystic fibrosis transmembrane conductance regulator) corrector for treating cystic fibrosis (CF) patients who carry the F508del mutation. Target: CFTR, Autophagy. Smiles: CCOc1ccc2c(nn(CC(=O)N(C)c3ccc4nc(C)oc4c3)c(=O)c2c1)-c1cccc(F)c1. References:...
| Keywords: | FDL169 |
| MW: | 486.49 D |
From 32.00€
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V-9302
Item number: TGM-T5345-200mg
Description: V-9302 (V9302) is a competitive antagonist of transmembrane glutamine flux that selectively and potently targets the amino acid transporter ASCT2 (IC50: 9.6 uM). Target: ASCT, Others. Smiles: Cc1cccc(COc2ccccc2CN(CC[C@H](N)C(O)=O)Cc2ccccc2OCc2cccc(C)c2)c1. References: 1. Schulte ML, et al....
| MW: | 538.68 D |
From 34.00€
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