Products from TargetMol

TargetMol

TargetMol, based in Boston, Massachusetts, was founded in 2015 and is a drug screening expert in the life science community. The company offers diverse compound libraries, including FDA-approved libraries, and covers a broad spectrum of small molecule compounds such as inhibitors and agonists as well as recombinant proteins and natural products. TargetMol's products are used by researchers worldwide in areas such as cancer research, neurobiology, inflammation, immunology and metabolism.

More information at: www.targetmol.com

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12268 from 12274 pages
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MS117
MS117

Item number: TGM-T60662-100mg

Description: MS117 is a first-in-class, cell-active, irreversible covalent inhibitor of protein arginine methyltransferase 6 (PRMT6) with an IC50 of 18 nM [1]. Target: Others
MW: 298.38 D
From 1,023.00€ *
Review
GSD-11
GSD-11

Item number: TGM-T60672-100mg

Description: GSD-11 inhibits the Akt/mTOR signaling pathway. GSD-11 inhibits the PANC-1 cells migration and colony formation. GSD-11 is a potent and selective anti-austerity agent that has the potential for the pancreatic cancer research [1]. Target: Others
MW: 300.44 D
From 1,440.00€ *
Review
FPDT
FPDT

Item number: TGM-T60676-100mg

Description: FPDT shows anti-glioblastoma activity which is linked to downregulation of the AKT pathway. FPDT has the IC 50 values >100 µM for astrocytes and 45-68 µM for GBM cells [1]. Target: Others
MW: 301.34 D
From 1,440.00€ *
Review
Elongation factor P-IN-2
Elongation factor P-IN-2

Item number: TGM-T60682-100mg

Description: Elongation factor P-IN-2, a beta-lysine derivative, is a potent inhibitor of elongation factor P (EFP) that affects E. coli proliferation rates [1]. Target: Others
MW: 301.47 D
From 1,440.00€ *
Review
A1AR antagonist 1
A1AR antagonist 1

Item number: TGM-T60687-100mg

Description: A1AR antagonist 1 (compound 18g) is a potent A1 adenosine receptor (AR) antagonist with Ki values of 2.08, 6.91, and 31.2 nM for hA1, hA2A, and hA2B, respectively [1]. Target: Others
MW: 302.33 D
From 1,440.00€ *
Review
Glutamate-5-kinase-IN-1
Glutamate-5-kinase-IN-1

Item number: TGM-T60693-100mg

Description: Glutamate-5-kinase-IN-1 (compound 50) is a potent G5K inhibitor that modifies the ATP binding site architecture for enzyme recognition (MIC = 4.1 µM) and has potential for anti-TB research [1]. Target: Others
MW: 302.37 D
From 1,440.00€ *
Review
Cedazuridine hydrochloride
Cedazuridine hydrochloride

Item number: TGM-T60708-100mg

Description: Cedazuridine (E7727) (Compound 7a) hydrochloride, an orally active cytidine deaminase (CDA) inhibitor with an IC50 of 0.4 µM, can be used for cancer research [1]. Target: Others
MW: 304.68 D
From 1,440.00€ *
Review
TK-129
TK-129

Item number: TGM-T60713-100mg

Description: TK-129 is an orally active, potent inhibitor of KDM5B with an IC50 of 44 nM and is low-toxicity. TK-129 exhibits cardioprotective effects by inhibiting KDM5B and blocking the KDM5B-associated Wnt pathway. TK-129 can be used in cardiovascular disease studies to reduce isoprenaline-induced myocardial...
MW: 305.38 D
From 747.00€ *
Review
Prohibitin ligand 1
Prohibitin ligand 1

Item number: TGM-T60722-100mg

Description: Prohibitin ligand 1 (Compound 22i) is a cardioprotective prohibitin ligand that shows in vitro cardioprotective activities at nanomolar concentrations, inducing the pro-survival factor STAT3 phosphorylation [1]. Target: Others
MW: 306.4 D
From 1,440.00€ *
Review
URAT1 inhibitor 3
URAT1 inhibitor 3

Item number: TGM-T60724-100mg

Description: URAT1 inhibitor 3 is a potent, orally active, selective inhibitor of URAT1 (IC50 = 0.8 nM) demonstrating urate-lowering efficacy, suitable for research in gout and hyperuricemia [1]. Target: Others
MW: 307.13 D
From 1,440.00€ *
Review
TMX-4113
TMX-4113

Item number: TGM-T60740-100mg

Description: TMX-4113 has potential to be used in cancer that is a phosphodiesterase 6D(PDE6D) and casein kinase 1alpha(CK1alpha) degrader [1]. Target: Others
MW: 308.38 D
From 1,327.00€ *
Review
HDAC10-IN-2
HDAC10-IN-2

Item number: TGM-T60760-100mg

Description: HDAC10-IN-2 (compound 10c) is a potent and highly selective HDAC10 inhibitor (IC50 = 20 nM) that regulates autophagy in aggressive FLT3-ITD positive acute myeloid leukemia cells [1]. Target: Others
MW: 310.39 D
From 1,440.00€ *
Review
12268 from 12274 pages