Products from South Bay Bio
South Bay Bio is a biotechnology company dedicated to providing high-troughput screening (HTS)-related products with a focus on the ubiquitin proteasome system. The company was formed in the San Francisco Bay area to support local biotechnology companies. The headquarters is located in San José, California.
More information at: www.adipogen.com/southbaybio
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Ubiquitin (human) (rec.) (Europium-Cryptate)
Item number: SBB-TR0014-C020
Ubiquitin is a highly conserved protein that plays a major role in the ubiquitination pathway, which is conserved from yeast to mammals. Ubiquitination, the conjugation of ubiquitin to other proteins through a covalent bond between its C-terminal glycine and the epsilon-amino group of lysine residues or the...
| Keywords: | UBB, Ubiquitin B |
| Application: | Assays |
| Expressed in: | E.coli |
| Origin: | human |
| MW: | 10 kD |
5,035.00€
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TRF-Ubiquitin Mix (100X) (2000 reactions)
Item number: SBB-TR0051-2K-1
Ubiquitin is a highly conserved protein that plays a major role in the ubiquitination pathway, which is conserved from yeast to mammals. Ubiquitination, the conjugation of ubiquitin to other proteins through a covalent bond between its C-terminal glycine and the epsilon-amino group of lysine residues or the...
| Keywords: | TRF-Ub Mix, UBB |
| Application: | Ubiquitination studies |
| Expressed in: | E.coli |
| Origin: | human |
| MW: | 8.5-8.9 kD |
6,030.00€
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![Ubiquitin Activating Enzyme E1 [UBA1] (human) (rec.) (His)](https://www.biomol.com/media/image/84/ec/2d/SBB-CE0058-C050_200x200.png "Ubiquitin Activating Enzyme E1 [UBA1] (human) (rec.) (His)")
Ubiquitin Activating Enzyme E1 [UBA1] (human) (rec.) (His)
Item number: SBB-CE0058-C050
Protein. Human UBA1 (aa12-1058) is fused at the N-terminus to a His-tag. Source: Sf21 cells. Liquid. In 50mM HEPES pH 7.5, 150mM sodium chloride, 10% glycerol, 2mM TCEP. Purity: >95% (SDS-PAGE). UBA1, the canonical ubiquitin E1 activating enzyme is a 118kDa protein, which forms a homodimer in its active state and...
| Keywords: | Ubiquitin E1 Enzyme, Ubiquitin-like Modifier-activating Enzyme 1, A1S9T, AMCX1, GXP1, POC20, SMAX2 |
| Expressed in: | Insect cells |
| Origin: | human |
| MW: | 120 kD |
334.00€
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Cullin4a/Rbx1/DDB1/CRBN E3 Ligase Complex TR-FRET Kit
Item number: SBB-KF0120-KI01
South Bay Bio's Cullin4a/Rbx1/DDB1/CRBN Neddylated E3 Ligase TR-FRET Kit provides a fast and sensitive method monitoring ubiquitin conjugation onto the E3 complex in solution, resulting from an enzymatic ubiquitin cascade without the need of running and staining an SDS gel. The kit enables continuous TR-FRET...
| Keywords: | CUL4A, CUL-4A, Cullin-4A |
| Application: | Compound Screening |
| Species reactivity: | human |
1,433.00€
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HA-Ubiquitin-vinyl methyl ester (human) (rec.) (HA)
Item number: SBB-PS0123-C050
Protein. Human ubiquitin (aa1-76) (Accession Nr. P0CG47) with a C-terminal vinyl methyl ester group and a N-terminal HA-Tag. Source: E. coli. Liquid. In 50mM MES pH 6.0, 100mM sodium chloride. Purity: >97% (LCMS). Ubiquitin is a small (8.5kDa) regulatory protein that has been found in almost all tissues of...
| Keywords: | HA-Ub-VME, HA-Ubiquitin-VME, HA-Ubiquitin-Vinyl methyl ester |
| Expressed in: | E. coli |
| Origin: | human |
| MW: | 10 kD |
420.00€
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HA-Ubiquitin-propargylamide (human) (rec.) (HA)
Item number: SBB-PS0124-C050
Protein. Human ubiquitin (aa1-76) (Accession Nr. P0CG47) with a C-terminal propargylamide group and a N-terminal HA-tag. Source: E. coli. Liquid. In 50mM MES pH 6.0, 100mM sodium chloride. Purity: >97% (LCMS). Ubiquitin is a small (8.5kDa) regulatory protein that has been found in almost all tissues of eukaryotic...
| Keywords: | HA-Ub-PA, HA-Ubiquitin-PA, HA-Ubiquitin-Propargylamide |
| Expressed in: | E. coli |
| Origin: | human |
| MW: | 10 kD |
420.00€
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![UbcH1 [UBE2K, E2-25K] (human) (rec.) (His)](https://www.biomol.com/media/image/5f/ea/64/SBB-CE0022-C100_200x200.png "UbcH1 [UBE2K, E2-25K] (human) (rec.) (His)")
UbcH1 [UBE2K, E2-25K] (human) (rec.) (His)
Item number: SBB-CE0022-C100
UBE2K (UbcH1) is an E2 ubiquitin conjugating enzyme. An E1 activating enzyme is required to attach ubiquitin to UBE2K via an active site cysteine. The mechanism of ubiquitin transfer involves the breaking of a E1-Ub thioester linkage, followed by a reformation of a UBE2K-Ub thioester. UBE2K is capable of...
| Keywords: | Ubiquitin-conjugating Enzyme E2, E2-25K, Hip2, HYPG, LIG, UBE2K, UBE2K-25K, Huntingtin-interacting Protein 2 |
| Application: | Assays |
| Expressed in: | E.coli |
| Origin: | human |
| MW: | 22 kD |
396.00€
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![UbcH5b [UBE2D2] (human) (rec.) (untagged)](https://www.biomol.com/media/image/0d/6f/b3/SBB-CE0027-C100_200x200.png "UbcH5b [UBE2D2] (human) (rec.) (untagged)")
UbcH5b [UBE2D2] (human) (rec.) (untagged)
Item number: SBB-CE0027-C100
UBE2D2 (UbcH5b) is an E2 ubiquitin conjugating enzyme. An E1 activating enzyme is required to attach ubiquitin to UBE2D2 via an active site cysteine. The mechanism of ubiquitin transfer involves the breaking of a E1-Ub thioester linkage, followed by a reformation of a UBE2D2-Ub thioester. UBE2D2 is capable of...
| Keywords: | Ubiquitin-conjugating Enzyme H5b, PUBC1, UBC5B, Ubiquitin-protein Ligase D2, p53-regulated Ubiquitin-conjugating Enzyme 1 |
| Application: | Assays |
| Expressed in: | E.coli |
| Origin: | human |
| MW: | 17 kD |
396.00€
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UcH-L3 (human) (rec.) (untagged)
Item number: SBB-DE0023-C050
UCHL3 (Ubiquitin C-terminal Hydrolase L3) is a deubiquitinating enzyme (DUB) that controls levels of cellular ubiquitin through processing of ubiquitin precursors and ubiquitinated proteins. It is a thiol protease that recognizes and hydrolyzes a peptide bond at the C-terminal glycine of either ubiquitin or NEDD8....
| Keywords: | Ubiquitin C-terminal Hydrolase L3, Ubiquitin Thioesterase L3 |
| Application: | Assays |
| Expressed in: | E.coli |
| Origin: | human |
| MW: | 26 kD |
319.00€
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![NEDP1 [SENP8] (human) (rec.) (His)](https://www.biomol.com/media/image/df/17/95/SBB-DE0025-C050_200x200.png "NEDP1 [SENP8] (human) (rec.) (His)")
NEDP1 [SENP8] (human) (rec.) (His)
Item number: SBB-DE0025-C050
NEDP1 is a deconjugating enzyme with specificity towards NEDDylated substrates. NEDP1 discriminates between ubiquitinated and NEDDylated targets, despite similar C-terminal regions. NEDP1 is a protease which hydrolyzes the isopeptide bond between the C-terminus of NEDD8 and the respective lysine of the substrate...
| Keywords: | NEDD8-specific Protease 1, Sentrin-specific Protease 8, Deneddylase-1, Sentrin/SUMO-specific Protease SENP8, DEN1, PRSC2 |
| Application: | Assays |
| Expressed in: | E.coli |
| Origin: | human |
| MW: | 27 kD |
278.00€
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SENP1 (catalytic domain) (human) (rec.) (His)
Item number: SBB-DE0026-C050
SUMO/Sentrin Specific Peptidase 1 (SENP1) is a member of the SENP family of proteases, which belong to the group of cysteine-type peptidases. SENP1 is a SUMO-specific enzyme that catalyzes two essential functions. Processing the full-length versions of SUMO1, SUMO2 and SUMO3 into its mature forms and the...
| Keywords: | Sentrin-specific Protease 1, Sentrin/SUMO-specific Protease SENP1 |
| Application: | Assays |
| Expressed in: | E.coli |
| Origin: | human |
| MW: | 32 kD |
316.00€
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Parkin E3 Ligase TR-FRET Kit
Item number: SBB-KF0036-KI01
South Bay Bio's Parkin TR-FRET Ubiquitin Kit provides a fast and sensitive method monitoring ubiquitin conjugation onto both wild-type Parkin and a more active mutant W403A in solution, resulting from an enzymatic ubiquitin cascade without the need of running and staining an SDS gel. The kit enables continuous...
| Keywords: | PRKN, PARK2, Parkin, Parkinson disease protein 2, E3 ubiquitin-protein ligase parkin, Parkinson juvenile disease protein 2 |
| Application: | Enzyme assays |
| Species reactivity: | human |
1,433.00€
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