Products from South Bay Bio

South Bay Bio

South Bay Bio is a biotechnology company dedicated to providing high-troughput screening (HTS)-related products with a focus on the ubiquitin proteasome system. The company was formed in the San Francisco Bay area to support local biotechnology companies. The headquarters is located in San José, California.

More information at: www.adipogen.com/southbaybio

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Z-Leu-Leu-Glu-AMC [Z-LLE-AMC]
Z-Leu-Leu-Glu-AMC [Z-LLE-AMC]

Item number: SBB-PS0006-M002

Lyophilized powder. Soluble in DMSO. Z-LLE-AMC is a fluorogenic peptide substrate for measuring caspase-like activity of the proteasome. Hydrolysis of this substrate by the beta1-subunit of the 20S proteasome is monitored by observing fluorescence at an Excitation wavelength of 345nm and Emission at 445nm. This...
Keywords: Proteasome Substrate II
Application: Fluorogenic peptide substrate
MW: 664,8 D
234.00€ *
Review
Ac-Pro-Ala-Leu-AMC [Ac-PAL-AMC]
Ac-Pro-Ala-Leu-AMC [Ac-PAL-AMC]

Item number: SBB-PS0007-M002

Lyophilized powder. Soluble in DMSO. Ac-PAL-AMC is a fluorogenic peptide substrate for measuring caspase-like activity of the immunoproteasome. Hydrolysis of this substrate by the beta1i-subunit of the immunoproteasome is monitored by observing fluorescence at an Excitation wavelength of 345nm and Emission at 445nm....
Keywords: Proteasome Substrate
Application: Fluorogenic peptide substrate
MW: 498,6 D
234.00€ *
Review
Ac-Ala-Asn-Trp-AMC [Ac-ANW-AMC]
Ac-Ala-Asn-Trp-AMC [Ac-ANW-AMC]

Item number: SBB-PS0009-M002

Lyophilized powder. Soluble in DMSO. Ac-ANW-AMC is a fluorogenic peptide substrate for measuring chymotrypsin-like activity of the immunoproteasome. Hydrolysis of this substrate by the beta5i-subunit of the immunoproteasome is monitored by observing fluorescence at an Excitation wavelength of 345nm and Emission at...
Keywords: Proteasome Substrate
Application: Fluorogenic peptide substrate
MW: 588,6 D
234.00€ *
Review
Suc-Leu-Leu-Val-Tyr-AMC [Suc-LLVY-AMC]
Suc-Leu-Leu-Val-Tyr-AMC [Suc-LLVY-AMC]

Item number: SBB-PS0010-M002

Lyophilized powder. Soluble in DMSO. Suc-LLVY-AMC is a fluorogenic substrate for measuring the chymotrypsin-like peptidase activity of the 20S and 26S proteasome, calpains and other chymotrypsin-like proteases. Cleavage of the peptide by the enzymes liberates the fluorophore AMC which generates strong increase in...
Keywords: Proteasome Substrate
Application: Fluorogenic peptide substrate
MW: 763,9 D
117.00€ *
Review
SUMO1 (human) (rec.) (Rhodamine 110)
SUMO1 (human) (rec.) (Rhodamine 110)

Item number: SBB-PS0028-C050

SUMO1 is a ubiquitin-like protein that can be covalently attached to proteins as a monomer or a lysine-linked polymer. Covalent attachment via an isopeptide bond to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I and can be promoted by E3 ligases such as...
Keywords: Small Ubiquitin-related Modifier 1, GAP-modifying Protein 1, SMT3C, SMT3H3, UBL1, Sentrin, Ubiquitin-homology Domain...
Application: Assays
Expressed in: E.coli
Origin: human
MW: 12 kD
497.00€ *
Review
20S Constitutive Proteasome Assay Kit
20S Constitutive Proteasome Assay Kit

Item number: SBB-KP0038-KI01

South Bay Bio's kit is designed to test for specific activity of 20S proteasome. The kit provides purified 20S proteasome and is designed to test for Chymotrypsin-like activity (Suc-LLVY-AMC), Caspase-like activity of the proteasome subunits beta1/PSMB6 (LLE-AMC) and Chymotrypsin-like activity of beta5/PSMB5...
Application: Compound Screening
717.00€ *
Review
UbcH5c [UBE2D3] (human) (rec.) (untagged)
UbcH5c [UBE2D3] (human) (rec.) (untagged)

Item number: SBB-CE0019-C100

UBE2D3 [UbcH5c] is an E2 ubiquitin conjugating enzyme. An E1 activating enzyme is required to attach ubiquitin to UBE2D3 via an active site cysteine. The mechanism of ubiquitin transfer involves the breaking of a E1-Ub thioester linkage, followed by a reformation of a UBE2D3-Ub thioester. UBE2D3 is capable of...
Keywords: Ubiquitin-conjugating Enzyme H5c, PUBC, UBC5C, Ubiquitin-protein Ligase D3, p53-regulated Ubiquitin-conjugating Enzyme
Application: Assays
Expressed in: E.coli
Origin: human
MW: 17 kD
396.00€ *
Review
UbcH7 [UBE2L3] (human) (rec.) (untagged)
UbcH7 [UBE2L3] (human) (rec.) (untagged)

Item number: SBB-CE0020-C100

UBE2L3 (UbcH7) is an E2 ubiquitin conjugating enzyme and accepts ubiquitin from an E1 activating enzyme via an active site cysteine. The mechanism of ubiquitin transfer involves the breaking of a E1-Ub thioester linkage, followed by a reformation of a UBE2L3-Ub thioester. UBE2L3 transfers active ubiquitin molecules...
Keywords: Ubiquitin-conjugating Enzyme E2 L3, E2-F1, L-UBC, UBCE7, UbcM4, UBE2L3, Ubiquitin-protein Ligase L3
Application: Assays
Expressed in: E.coli
Origin: human
MW: 18 kD
396.00€ *
Review
20S Immunoproteasome (human) (untagged)
20S Immunoproteasome (human) (untagged)

Item number: SBB-PP0004-C025

The 20S immunoproteasome is structurally similar to constitutive 26S proteasome. The 20S core of immunoproteasome contains two outer rings composed of alpha-subunits, and two internal 7-subunit containing rings each possessing 3 specific subunits responsible for proteasome catalytic activity. In immunoproteasomes...
Application: Assays
Expressed in: Human cells
Origin: human
MW: 700 kD
464.00€ *
Review
ISG15 (human) (rec.) (Rhodamine 110)
ISG15 (human) (rec.) (Rhodamine 110)

Item number: SBB-PS0002-C050

ISG15 (Interferon Stimulated Gene, 15kDa) is a ubiquitin-like modifier which initiates innate immune response by activating RIG-I signaling, stimulating NK-cell proliferation, inhibiting viral budding and acting as an IFNgamma-inducing cytokine. ISG15 contains two tandem ubiquitin homology domains and is...
Keywords: ISG15 Ubiquitin-like Modifier, G1P2, IFI15, IP17, UCRP
Application: Assays
Expressed in: E.coli
Origin: human
MW: 18 kD
497.00€ *
Review
Ac-Trp-Leu-Ala-AMC [Ac-WLA-AMC]
Ac-Trp-Leu-Ala-AMC [Ac-WLA-AMC]

Item number: SBB-PS0008-M002

Lyophilized powder. Soluble in DMSO. Ac-WLA-AMC is a fluorogenic peptid substrate for measuring chymotrypsin-like activity of the proteasome. Hydrolysis of this substrate by the beta5-subunit of the 20S proteasome is monitored by observing fluorescence at an Excitation wavelength of 345nm and Emission at 445nm. This...
Keywords: Proteasome Substrate
Application: Fluorogenic peptide substrate
MW: 587,7 D
234.00€ *
Review
SUMO2 (human) (rec.) (Rhodamine 110)
SUMO2 (human) (rec.) (Rhodamine 110)

Item number: SBB-PS0029-C050

SUMO2 is a Ubiquitin-like protein (UBL) that can be covalently attached to proteins as a monomer or as a lysine-linked polymer. Covalent attachment via an isopeptide bond to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, and can be promoted by an E3 ligase...
Keywords: Small Ubiquitin-related Modifier 2, HSMT3, SMT3 Homolog 2, Sentrin-2, Ubiquitin-like Protein SMT3A
Application: Assays
Expressed in: E.coli
Origin: human
MW: 11 kD
497.00€ *
Review
2 from 7 pages