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Item number: Cay39728-1
Buccalin A is a neuropeptide that is found in gastropod motor neurons and is involved in neuromuscular signaling. It reduces current-induced muscle contraction amplitude but not muscle relaxation rate in isolated and washed A. californica accessory radula closer (ARC) muscle fibers when used at a concentration of 10...
Keywords: | (3S,6S,9S,12S,15S,18S,27S)-3-((S)-2-(2-aminoacetamido)-4-(methylthio)butanamido)-15-benzyl-27-carbamoyl-6,18-bis(hydroxyme... |
Application: | Neuropeptide |
MW: | 1053.2 D |
From 39.00€
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Item number: Cay40142-1
PF-05190457 is an inverse agonist of the growth hormone secretagogue receptor (GHS-R), which is also known as the ghrelin receptor. It selectively binds to GHS-R (Ki = 4.37 nM) over M2 muscarinic acetylcholine receptors (mAChRs, Ki = 1,950 nM) and the serotonin (5-HT) receptor subtype 5-HT2B (IC50 = 3,700 nM)....
Keywords: | 1-[2-[(1R)-2,3-dihydro-5-(6-methyl-4-pyrimidinyl)-1H-inden-1-yl]-2,7-diazaspiro[3.5]non-7-yl]-2-(2-methylimidazo[2,1-b]thi... |
Application: | GHS-R inverse agonist |
CAS | 1334782-79-4 |
MW: | 512.7 D |
From 47.00€
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Item number: Cay40149-1
[pGlu4]-Myelin basic protein peptide is a substrate for PKC. It is selectively phosphorylated by PKC over PKA and phosphorylase kinase.Formal Name: 5-oxo-L-prolyl-L-lysyl-L-arginyl-L-prolyl-L-seryl-L-glutaminyl-L-arginyl-L-seryl-L-lysyl-L-tyrosyl-L-leucine, trifluoroacetate salt. Synonyms: [pGlu4]-MBP Peptide....
Keywords: | [pGlu4]-MBP Peptide,... |
Application: | PKC peptide substrate |
MW: | 1373.6 D |
From 34.00€
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Item number: Cay40150-1
Malantide is a synthetic peptide derived from the beta-subunit of human phosphorylase kinase and is a fluorescent substrate for PKA and PKC. Upon phosphorylation by PKA or PKC, the intrinsic tyrosine fluorescence decreases and can be used to quantify PKA and PKC activity. Malantide displays an emission at 302 nm...
Keywords: | L-arginyl-L-threonyl-L-lysyl-L-arginyl-L-serylglycyl-L-seryl-L-valyl-L-tyrosyl-L-alpha-glutamyl-L-prolyl-L-leucyl-L-lysyl-... |
Application: | Fluorescent PKA / PKC substrate |
MW: | 1633.9 D |
From 61.00€
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Item number: Cay40151-1
Myomodulin A is a gastropod neuropeptide. It is found in gastropod ventral lobe neurons, neural elements of the accessory radula closer (ARC) muscle, and penis nerve. Myomodulin A is biosynthesized by ARC motor neurons in A. californica and potentiates motor neuron-elicited contractions of the A. californica buccal...
Keywords: | MMa, MYOMOD1, Pro-Met-Ser-Met-Leu-Arg-Leu-NH2, L-prolyl-L-methionyl-L-seryl-L-methionyl-L-leucyl-L-arginyl-L-leucinamide,... |
Application: | Gastropod neuropeptide |
MW: | 846.1 D |
From 34.00€
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Item number: Cay40170-10
Semaglutide is an agonist of glucagon-like peptide 1 receptor (GLP-1R, EC50 = 6.2 pM in a reporter assay using BHK cells expressing the human receptor). It decreases blood glucose levels in the db/db mouse model of type 2 diabetes (ED50 = 98%. Formulation: (Request formulation change), A solid. Solubility:...
Keywords: | L-histidyl-2-methylalanyl-L-alpha-glutamylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-alpha-aspartyl-L-valyl-L-s... |
Application: | GLP-1R agonist |
CAS | 2924330-56-1 |
MW: | 4113.6 D |
From 117.00€
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Item number: Cay40231-1
Semaglutide is an agonist of glucagon-like peptide 1 receptor (GLP-1R, EC50 = 6.2 pM in a reporter assay using BHK cells expressing the human receptor). It decreases blood glucose levels in the db/db mouse model of type 2 diabetes (ED50 = 98%. Formulation: (Request formulation change), A solid. Solubility: Methanol:...
Application: | GLP-1R agonist |
CAS | 910463-68-2 |
MW: | 4113.6 D |
From 34.00€
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Item number: BOT-10402
NucView(R) 488 Caspase-3 Substrate is a novel cell membrane-permeable fluorogenic caspase substrate designed for detecting caspase-3/7 activity within live cells in real time. Unlike conventional caspase assays, NucView(R) 488 Caspase-3 Substrate detects caspase-3/7 activity within individual intact cells without...
From 111.00€
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Item number: BOT-10403
NucView(R) 488 Caspase-3 Substrate is a novel fluorogenic caspase substrate for real-time detection of caspase-3/7 activity in live cells. In apoptotic cells, the substrate is cleaved to release a DNA dye that stains the nucleus with bright green fluorescence. 1 mM in PBS, 100 uL.
From 111.00€
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Item number: BOT-10404
Ac-DEVD-CHO is a synthetic tetrapeptide competitive inhibitor for Caspase-3/7, and contains the amino acid sequence of the PARP cleavage site. Ac-DEVD-CHO can be used to inhibit Caspase-3/7 activity in apoptotic cells, and to study events downstream of Caspase-3/7 activation.Soluble in DMSOStore at 4°CC20H30N4O11MW:...
From 121.00€
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Item number: BOT-10405
NucView(R) 405 Caspase-3 Substrate, 1 mM in DMSO, provides a convenient tool for detecting apoptosis in intact cells based on caspase-3/7 activity using either confocal microscopy or flow cytometry. In contrast to other fluorogenic caspase substrates or fluorescent caspase inhibitor based (FLICA) assays, NucView(R)...
From 111.00€
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Item number: BOT-10406
NucView 530 Caspase-3 Substrate, 1 mM in DMSO, provides a convenient tool for detecting caspase activity in intact cells in real time by either fluorescence microscopy or flow cytometry, the substrate stains apoptotic cell nuclei with orange fluorescence (Ex/Em 528/563 nm).
From 111.00€
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