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Item number: ABD-13401
A fluorogenic substrate for caspase 3. The 7-amido-4-trifluoromethylcoumarin derivatives have better membrane permeability than the 7-amido-4-methylcoumarin derivatives.
Application: | Caspase-3 substrate |
CAS | 201608-14-2 |
139.00€
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Item number: ABD-13430
Cleavage of R110 peptides by caspases generates strongly fluorescent R110 that can be monitored fluorimetrically at 510-530 nm with excitation of 488 nm.This R110 substrate is specific for caspases 3 and 7.
Application: | Caspase-3 substrate, Caspase-7 substrate |
139.00€
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Item number: ABD-13402
A fluorogenic substrate for caspase 3, a protease that is rapidly activated when cells are exposed to apoptotic conditions and that cleaves poly(ADP-ribose) polymerase.
Application: | Caspase-3 substrate |
CAS | 169332-61-0 |
139.00€
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Item number: ABD-13467
The non-fluorescent R110 substrates generate the bright green fluorescent rhodamine 110 product that has Ex/Em = 494/521 nm, and can be easily detected with a FITC filter set. In general, R110 substrates are much more sensitive than the AMC-, AFC- or 4-nitroaniline-based substrates. This R110 substrate is used for...
Application: | Protease substrate |
139.00€
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Item number: Cay17598-50
3,3',5'-Triiodo-L-thyronine, also known as reverse T3 (rT3), is a thyroid hormone generated by deiodination of the prohormone thyroxine. It is about 1,000-fold less active at the thyroid hormone receptors TRalpha and TRbeta than 3,3',5-triiodo-L-thyronine (Cay-16028) and commonly described as inactive. However, high...
Keywords: | 3,3',5'-T3, Reverse T3, rT3, O-(4-hydroxy-3,5-diiodophenyl)-3-iodo-L-tyrosine |
Application: | TR Delta alpha1 activator |
CAS | 5817-39-0 |
MW: | 651 D |
From 114.00€
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Item number: Cay17150-25
Angiotensin II is a peptide hormone known best as a vasoconstrictor with central roles in chronic hypertension, heart failure, and stroke. It is an octapeptide typically generated by the removal of two residues from angiotensin I by angiotensin-converting enzyme (ACE). Angiotensin II is a ligand for at least two...
Keywords: | 5-L-isoleucine-angiotensin II, acetate |
Application: | Peptide hormone |
CAS | 68521-88-0 |
MW: | 1046.2 D |
From 34.00€
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Item number: Cay24204-1
Glucagon is a peptide hormone produced from proglucagon in pancreatic alpha cells that has a role in the regulation of glucose metabolism. Pulsatile application of glucagon to rat hepatocytes stimulates glucose production ex vivo. It also stimulates glucose output from perfused rat livers via increases in...
Keywords: | glucagon (swine) |
Origin: | swine |
CAS | 19179-82-9 |
MW: | 3482.8 D |
From 117.00€
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Item number: BPS-40560
PI/PS (4:1, w/w) unilamellar vesicle, prepared with L-alpha-phosphatidylinositol (Liver, Bovine) (sodium salt) and L-alpha-phosphatidylserine (Brain, Porcine) (sodium salt). Lipid monolayer was formed by sonication. Application: Useful as a substrate for PI-3 kinase activity assays and other lipid kinases....
Application: | PI-3 kinase substrate |
569.00€
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NEW
Item number: Cay35692-100
Sulfo-SMCC is a water-soluble protein cross-linking reagent that contains an anime-reactive sulfo-N-hydroxysuccinimide (sulfo-NHS) ester and a sulfhydryl-reactive maleimide group that can be used in the conjugation of proteins. It has been used to conjugate anti-programmed cell death ligand 1 (PD-L1) antibodies to...
Keywords: | Sulfosuccinimidyl 4-(N-maleimidomethyl)cyclohexane-1-carboxylate,... |
Application: | Water-soluble protein cross-linking reagent |
CAS | 92921-24-9 |
MW: | 436.4 D |
From 92.00€
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NEW
Item number: Cay36949-1
LL-37 (13-37) is an anticancer peptide fragment of LL-37 (Cay-24461). It inhibits the ATPase activity of ATP-binding cassette transporter 2, subfamily G (ABCG2) when used at a concentration of 1 µM. LL-37 (13-37) induces cytotoxicity in wild-type SW620 cells and SW620 cells overexpressing P-glycoprotein (P-gp), also...
Keywords: | CAP-18, Cathelicidin, FALL-39, hCAP-18, IG-25, LL-13, LL-25,... |
Application: | LL-37 anticancer peptide fragment |
MW: | 3043.6 D |
From 53.00€
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NEW
Item number: Cay38849-1
Chemokine (C-X-C motif) ligand 9 (CXCL9) (74-103) is a C-terminal fragment of mature CXCL9. It binds to the glycosaminoglycan heparin in a cell-free assay (Kd = 3.1 nM). CXCL9 (74-103) inhibits the binding of CXCL8 or CXCL11 to heparin, as well as chemokine (C-C motif) ligand 2 (CCL2) binding to heparan sulfate, in...
Keywords: | Chemokine (C-X-C motif) Ligand 9 (74-103), MIG30, Monokine Induced by Interferon-gamma (74-103) |
Application: | CXCL9-derived peptide |
MW: | 3661.4 D |
From 66.00€
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NEW
Item number: Cay39017-1
[Ala1,3,11,15]-Endothelin-1 is an endothelin receptor type B (ETB) agonist and linear synthetic peptide derivative of endothelin-1 in which all four cysteine residues have been substituted with alanine. It selectively binds to ETB over ETA receptors (IC50s = 0.33 and 570 nM, respectively, for the porcine receptors)....
Keywords: | [Ala1,3,11,15]-ET-1, 4-Ala-ET-1,... |
Application: | ETB receptor agonist |
MW: | 2367.7 D |
From 53.00€
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