Lipids

Lipids are organic small molecules, that are usually hydrophobic or amphiphillic. This group includes fat, fatty acids, waxes, triglycerides, sterols and phospholipids for example. Lipids are the main structural component of biological membranes of all cells. As such bacterial lipid structures and glycolipids can serve as pathogen-associated-molecular-patterns (PAMPs) and are recognized by our immune system. Various lipids of bacterial origin are therefore used as immunostimulants.

Lipids are organic small molecules, that are usually hydrophobic or amphiphillic. This group includes fat, fatty acids, waxes, triglycerides, sterols and phospholipids for example. Lipids are the... read more »
Close window
Lipids

Lipids are organic small molecules, that are usually hydrophobic or amphiphillic. This group includes fat, fatty acids, waxes, triglycerides, sterols and phospholipids for example. Lipids are the main structural component of biological membranes of all cells. As such bacterial lipid structures and glycolipids can serve as pathogen-associated-molecular-patterns (PAMPs) and are recognized by our immune system. Various lipids of bacterial origin are therefore used as immunostimulants.

1 from 300 pages
No results were found for the filter!
(±)14(15)-DiHETE MaxSpec(R) Standard
(±)14(15)-DiHETE MaxSpec(R) Standard

Item number: Cay29140-10

(±)14(15)-DiHETE is an oxylipin and a metabolite of the omega-3 fatty acid eicosapentaenoic acid (EPA, Cay-90110, Cay-90110.1, Cay-21908). It is formed via cytochrome P450-mediated epoxidation of EPA to (±)14(15)-EpETE (Cay-10173), followed by conversion of the epoxide to a diol by soluble epoxide hydrolase....
Keywords: (±)14,15-dihydroxy-5Z,8Z,11Z,17Z-eicosatetraenoic acid, (±)14,15-dihydroxy-eicosa-5,8,11,17-Tetraenoic Acid
Application: MS, Quantitative grade standard
CAS 119433-37-3
MW: 336.5 D
158.00€ *
Review
14(S)-HDHA MaxSpec(R) Standard
14(S)-HDHA MaxSpec(R) Standard

Item number: Cay29142-10

14(S)-HDHA is an oxygenation product formed by 12-lipoxygenase (12-LO) or 15-LO processing of docosahexaenoic acid (DHA, Cay-90310). It is a precursor to the pro-resolving mediator maresin 1 (Cay-10878) and has been found in peritoneal exudates isolated from a mouse model of zymosan-induced peritonitis. 14(S)-HDHA...
Keywords: 14S-hydroxy-4Z,7Z,10Z,12E,16Z,19Z-docosahexaenoic acid, 14(S)-hydroxy Docosahexaenoic Acid, 14(S)-HDoHE
Application: MS, Quantitative grade standard
CAS 119433-37-3
MW: 344.5 D
132.00€ *
Review
Prostaglandin E1
Prostaglandin E1

Item number: Cay13010-5

PGE1 is the theoretical cyclooxygenase metabolite of dihomo-gamma-linolenic acid (DGLA), but it is virtually undetectable in the plasma of normal humans or other animals. Its pharmacology includes vasodilation, hypotension, and anti-platelet activities. The IC50 of PGE1 for the inhibition of ADP-induced human...
Keywords: Alprostadil, PGE1, 9-oxo-11alpha,15S-dihydroxy-prost-13E-en-1-oic acid
Application: Bioactive lipid assays
CAS 745-65-3
MW: 354.5 D
From 22.00€ *
Review
(±)14(15)-EpETE
(±)14(15)-EpETE

Item number: Cay10173-25

EDHF (endothelium-derived hyperpolarizing factor) is an unidentified mediator released from vascular endothelial cells in response to acetylcholine and bradykinin which is distinct from the NOS- (nitric oxide) and COX-derived (prostacyclin) vasodilators. Cytochrome P450 (CYP450) metabolism of polyunsaturated fatty...
Keywords: (±)14,15 EEQ, (±)14,15-epoxy Eicosatetraenoic Acid, (±)14,15-epoxy-5Z,8Z,11Z,17Z-eicosatetraenoic acid
Application: Bioactive lipid assays
CAS 131339-24-7
MW: 318.5 D
From 48.00€ *
Review
Leukotriene E4
Leukotriene E4

Item number: Cay20410-25

Leukotriene E4 (LTE4) is produced by the action of dipeptidase on LTD4, leaving only the cysteinyl group still attached to the fatty acid backbone. It is one of the constituents of slow-reacting substance of anaphylaxis (SRS-A). LTE4 is considerably less active (8 to 12-fold) than LTC4 in the biological activities...
Keywords: LTE4, 5S-hydroxy-6R-(S-cysteinyl)-7E,9E,11Z,14Z-eicosatetraenoic acid
Application: Bioactive lipid assays
CAS 75715-89-8
MW: 439.6 D
From 90.00€ *
Review
8(S),15(S)-DiHETE
8(S),15(S)-DiHETE

Item number: Cay35370-25

8(S),15(S)-DiHETE is formed when 15(S)-HETE is subjected to further oxidation by 15-LO. It causes eosinophil chemotaxis with an ED50 value of 1.5 µM but is not chemotactic for neutrophils. 8(S),15(S)-DiHETE antagonizes the hyperalgesic activity of 8(R),15(S)-DiHETE and LTB4 in the rat hind paw pain model.
Keywords: 8S,15S-dihydroxy-5Z,9E,11Z,13E-eicosatetraenoic acid
Application: Bioactive lipid studies
CAS 80234-65-7
MW: 336.5 D
From 97.00€ *
Review
Docosapentaenoic Acid
Docosapentaenoic Acid

Item number: Cay90165-1

Docosapentaenoic acid is an omega-3 fatty acid found in fish oils. It is a minor constituent of the total serum unsaturated fatty acids in humans, ranging from 0.1 to 1%, and increases on dietary supplementation.
Keywords: DPA, 7Z,10Z,13Z,16Z,19Z-docosapentaenoic acid
Application: Bioactive lipid assays
CAS 24880-45-3
MW: 330.5 D
From 32.00€ *
Review
Prostaglandin A1
Prostaglandin A1

Item number: Cay10010-50

Prostaglandin A1 (PGA1) was first isolated as a dehydration product of the PGE1 compounds found in human semen. It has been shown to cause renal vasodilation, increased urine sodium excretion, and lowered arterial pressure in hypertensive patients. It also has growth-inhibitory activity on tumor cells, the IC50...
Keywords: PGA1, 9-oxo-15S-hydroxy-prosta-10,13E-dien-1-oic acid
Application: Bioactive lipid assays
CAS 14152-28-4
MW: 336.5 D
From 35.00€ *
Review
Prostaglandin D2
Prostaglandin D2

Item number: Cay12010-1

Prostaglandin D2 (PGD2) is the major eicosanoid product of mast cells and is released in large quantities during allergic and asthmatic anaphylaxis. Mastocytosis patients produce excessive amounts of PGD2, which causes vasodilation, flushing, hypotension, and syncopal episodes. PGD2 is also produced in the brain via...
Keywords: PGD2, 9alpha,15S-dihydroxy-11-oxo-prosta-5Z,13E-dien-1-oic acid
Application: Bioactive lipid assays
CAS 41598-07-6
MW: 352.5 D
From 49.00€ *
Review
Prostaglandin E2
Prostaglandin E2

Item number: Cay14010-1

PGE2 is one of the primary COX products of arachidonic acid (Cay-90010) and one of the most widely investigated prostaglandins. Its activity influences inflammation, fertility and parturition, gastric mucosal integrity, and immune modulation. The effects of PGE2 are transduced by at least four distinct receptors...
Keywords: Dinoprostone, PGE2, 9-oxo-11alpha,15S-dihydroxy-prosta-5Z,13E-dien-1-oic acid
Application: Bioactive lipid assays
CAS 363-24-6
MW: 352.5 D
From 25.00€ *
Review
16,16-dimethyl Prostaglandin E2
16,16-dimethyl Prostaglandin E2

Item number: Cay14750-1

16,16-dimethyl PGE2 is a competitive inhibitor of 15-hydroxy PGDH, but it is not a substrate for the enzyme. Because of its resistance to metabolism by 15-hydroxy PGDH, it has a prolonged half-life in vivo. 16,16-dimethyl PGE2 acts as an agonist on most EP receptor subtypes, and has been used experimentally to...
Keywords: 16,16-dimethyl PGE2, 9-oxo-11alpha,15R-dihydroxy-16,16-dimethyl-prosta-5Z,13E-dien-1-oic acid
Application: PGDH inhibitor
CAS 39746-25-3
MW: 380.5 D
From 87.00€ *
Review
6-keto Prostaglandin F1alpha-d4
6-keto Prostaglandin F1alpha-d4

Item number: Cay315210-25

6-keto Prostaglandin F1alpha-d4 (6-keto PGF1alpha-d4) contains four deuterium atoms at the 3, 3', 4, and 4' positions. It is intended for use as an internal standard for the quantification of 6-keto PGF1alpha (Cay-15210) by GC- or LC-MS. 6-keto PGF1alpha is the inactive, non-enzymatic hydrolysis product of PGI2....
Keywords: 6-keto PGF1alpha-d4, 6-oxo-9alpha,11alpha,15S-trihydroxy-prost-13E-en-1-oic-3,3,4,4-d4 acid
Application: Standard
CAS 82414-64-0
MW: 374.5 D
From 65.00€ *
Review
1 from 300 pages
Viewed