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Item number: AG-CN2-0031-M001
Isolated from Latrunculia magnifica. Cell permeable marine toxin. Disrupts microfilament-mediated processes. Actin polymerization inhibitor in vitro and in vivo by the formation of a 1:1 complex with monomeric G-actin. Less potent than Latrunculin A. May have fewer unwanted effects than latrunculin A and may be...
|Keywords:||LAT-B, NSC 339663|
|Application:||Actin polymerization inhibitor|
From 99.00€ *
Item number: AG-CR1-3615-M001
Crystalline solid. Soluble in water (10mg/ml), DMSO (10mg/ml), dimethyl formamide or ethanol (1mg/ml). Chemical. CAS: 256373-96-3. Formula: C20H23N2NaO5S. MW: 426.5. Synthetic. Potent, selective and orally available NLRP3 inflammasome inhibitor. Blocks the release of IL-1beta in macrophages primed with LPS and...
|Keywords:||MCC950, CP-456,773, CRID3, 1-(1,2,3,5,6,7-Hexahydro- s-indacen-4-yl)-3-[4-(1-hydroxy-1-methyl-ethyl)-furan-2-sulfonyl]urea|
|Application:||NLRP3 inflammasome inhibitor|
From 39.00€ *
Item number: Cay82220-50
As the active metabolite of molsidomine, SIN-1 (chloride) is a potent vasorelaxant and inhibitor of platelet aggregation. It produces both NO and superoxide and can therefore be used to generate peroxynitrite under physiological conditions.
|Keywords:||3-Morpholino-sydnonimine, Linsidomine, 5-amino-3-(4-morpholinyl)-1,2,3-oxadiazolium chloride|
From 18.00€ *
Item number: Cay30354-5
Remdesivir is a prodrug form of the antiviral nucleoside analog GS-441524 (Cay-30469). Upon entry into cells, remdesivir is metabolized into the nucleotide triphosphate GS-441524. Remdesivir is active against Middle East respiratory syndrome coronavirus (MERS-CoV) and severe acute respiratory syndrome CoV (SARS-CoV)...
|Keywords:||GS-5734, N-[(S)-hydroxyphenoxyphosphinyl)-L-alanine, 2-ethylbutyl ester, 6-ester with...|
|Application:||GS-441524 prodrug, SARS type antiviral|
From 219.00€ *
Item number: Cay16039-100
Imipenem is an intravenous beta-lactam antibiotic effective against a wide range of Gram-positive and Gram-negative bacteria (MICs range from 0.5-2 µg/ml for E. cloacae and P. aeruginosa), including several multi-drug resistant bacterial species. Imipenem acts by interfering with bacterial cell wall synthesis.
|Application:||Antibacterial antibiotic, Peptidoglycan biosynthesis inhibitor|
From 57.00€ *
Item number: 12136.100
Purity: >96.5%, A reversible inhibitor of trypsin-like proteases and cysteine proteases. Soluble in water, ethanol, acetic acid and DMF. Stock solution: 10 mM in water, stable for 1 month at -20 °C. Effective conc.: 1-10 µM.
From 83.00€ *
Item number: 02291.250
Soluble in DMF, hardly soluble in water. Use as alkaline phosphatase substrate forming a water insoluble blue reaction product. Often used together with NBT (Art.-Nr. 06428) for immunocytochemistry.
|Application:||Substrate for alkaline phosphatase|
From 53.00€ *
Item number: 15655.1
The water soluble MTT yields a yellowish solution. It is converted by mitochondrial dehydrogenases of metabolically active cells to an insoluble formazan product, which can be solubilized with DMSO. Read at 510 nm.
|Application:||Cell viability assay|
From 28.00€ *