- Search results for Q8WXC3
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9 products were found matching "Q8WXC3"!
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Item number: ABE-20-1006-50
ASC2/POP1 is a PAAD domain only protein originally identified in a bioinformatics screen aimed at understanding molecular apoptosis mechanisms .Human ASC2/POP1 is an 89 amino acid protein and migrates at ~10-12 kDa on SDS-PAGE gels. ASC2/POP1 has high amino acid sequence homology with ASC (64%), hence it was...
Keywords: | Anti-cPOP1, Anti-cellular POP1, Anti-PAAD-only protein 1, Anti-Pyrin-only protein 1, Anti-Pyrin domain-containing protein... |
Application: | IP, IHC, WB |
Host: | Rabbit |
Species reactivity: | rat, mouse, human |
373.00€
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Item number: ELK-ES13847.100
Protein function: Associates with PYCARD/ASC and modulates its ability to collaborate with MEFV/pyrin and NLRP3/cryopyrin in NF-kappa-B and pro- caspase-1 activation. Suppresses kinase activity of NF-kappa-B inhibitor kinase (IKK) complex, expression of NF-kappa-B inducible genes and inhibits NF-kappa-B activation...
Keywords: | Anti-cPOP1, Anti-cellular POP1, Anti-PAAD-only protein 1, Anti-Pyrin-only protein 1, Anti-Pyrin domain-containing protein... |
Application: | IHC, IF |
Host: | Rabbit |
Species reactivity: | human, rat, mouse, |
From 169.00€
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Item number: AG-40B-0123-C010
Human POP1 (aa 2-89) is fused at the N-terminus to a GST tag. Lyophilized. Contains PBS. The inflammasome is a multiprotein complex that mediates the activation of caspase-1, which promotes, amongst others, the secretion of the proinflammatory cytokines interleukin (IL)-1beta and IL-18. Members of the Nod-like...
Keywords: | ASC2, PYDC1, PAAD-only protein 1, Pyrin-only protein 1, Pyrin domain-containing protein 1 |
Application: | Bioassay |
Expressed in: | E.coli |
Origin: | human |
MW: | 38 kD |
From 171.00€
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Item number: VHPS-7521
Primers are provided as a 40 µl solution containing both primers at a final concentration of 50 µM in 10 mM Tris-HCl (pH 7.5), 0.1 mM EDTA. Dilute with water as needed prior to use. This amount is sufficient for 1000 x 20µl PCR reactions assuming a final primer concentration of 0.1 µM. Add cDNA template....
Keywords: | ASC2, PYDC1, PAAD-only protein 1, Pyrin-only protein 1, Pyrin domain-containing protein 1 |
Application: | RNA quantification |
43.00€
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Item number: 040708-APC.200
PYDC1 associates with apoptosis-associated specklike protein containing a CARD domain (ASC) and modulates its ability to collaborate with pyrin and cryopyrin in NF-kappa-B and pro-caspase-1 activation. Suppresses kinase activity of NF-kappa-B inhibitor kinase (IKK) complex, expression of NF-kappa-B inducible genes...
Keywords: | Anti-ASC2, Anti-PYDC1, Anti-PAAD-only protein 1, Anti-Pyrin-only protein 1, Anti-Pyrin domain-containing protein 1 |
Application: | FLISA, WB |
Host: | Rabbit |
Species reactivity: | human |
993.00€
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Item number: 040708-Biotin.200
PYDC1 associates with apoptosis-associated specklike protein containing a CARD domain (ASC) and modulates its ability to collaborate with pyrin and cryopyrin in NF-kappa-B and pro-caspase-1 activation. Suppresses kinase activity of NF-kappa-B inhibitor kinase (IKK) complex, expression of NF-kappa-B inducible genes...
Keywords: | Anti-ASC2, Anti-PYDC1, Anti-PAAD-only protein 1, Anti-Pyrin-only protein 1, Anti-Pyrin domain-containing protein 1 |
Application: | ELISA, WB |
Host: | Rabbit |
Species reactivity: | human |
993.00€
*
Item number: 040708-FITC.200
PYDC1 associates with apoptosis-associated specklike protein containing a CARD domain (ASC) and modulates its ability to collaborate with pyrin and cryopyrin in NF-kappa-B and pro-caspase-1 activation. Suppresses kinase activity of NF-kappa-B inhibitor kinase (IKK) complex, expression of NF-kappa-B inducible genes...
Keywords: | Anti-ASC2, Anti-PYDC1, Anti-PAAD-only protein 1, Anti-Pyrin-only protein 1, Anti-Pyrin domain-containing protein 1 |
Application: | FLISA, WB |
Host: | Rabbit |
Species reactivity: | human |
993.00€
*
Item number: 040708.200
PYDC1 associates with apoptosis-associated specklike protein containing a CARD domain (ASC) and modulates its ability to collaborate with pyrin and cryopyrin in NF-kappa-B and pro-caspase-1 activation. Suppresses kinase activity of NF-kappa-B inhibitor kinase (IKK) complex, expression of NF-kappa-B inducible genes...
Keywords: | Anti-ASC2, Anti-PYDC1, Anti-PAAD-only protein 1, Anti-Pyrin-only protein 1, Anti-Pyrin domain-containing protein 1 |
Application: | ELISA, WB |
Host: | Rabbit |
Species reactivity: | human |
728.00€
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Item number: P9522-75.50
ASC2/POP1 is a PAAD domain only protein originally identified in a bioinformatics screen aimed at understanding molecular apoptosis mechanisms (Pawtokski et al, 2001, reviewed in Fabiola et al, 2006, and Mariathasan and Vuvic, 2003.). ASC2/POP1 has high aa sequence homology with ASC (64%), hence it was originally...
Keywords: | Anti-PAAD-only protein 1, Anti-Pyrin-only protein 1, Anti-Pyrin domain-containing protein 1 |
Application: | IHC, IP, WB |
Host: | Rabbit |
Species reactivity: | human, mouse, rat |
516.00€
*