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Wee1 Inhibitor
Item number: Cay35391-1
Wee1 inhibitor is an inhibitor of the checkpoint kinase Wee1 (IC50 = 11 nM). It is selective for Wee1 over checkpoint kinase 1 (Chk1, IC50 = 440 nM). Wee1 inhibitor also inhibits the ATPase activity of LptB, an enzyme involved in the transport and assembly of LPS (IC50 = 25 µM for the E. coli enzyme).Formal Name:...
| Keywords: | 4-(2-chlorophenyl)-9-hydroxy-pyrrolo[3,4-c]carbazole-1,3(2H,6H)-dione |
| Application: | Wee1 inhibitor |
| CAS | 622855-37-2 |
| MW: | 362.8 D |
401.00€
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WEE1-IN-4
Item number: TGM-T23869-1mg
Description: Wee1 Inhibitor I is an ATP-binding site-targeting Wee1 inhibitor. Target: Others. Smiles: Oc1ccc2[nH]c3cc(c4C(=O)NC(=O)c4c3c2c1)-c1ccccc1Cl. References: Schmidt M, Rohe A, Platzer C, Najjar A, Erdmann F, Sippl W. Regulation of G2/M Transition by Inhibition of WEE1 and PKMYT1 Kinases. Molecules. 2017 Nov...
| Keywords: | Wee1 Inhibitor-I, Wee1 Inhibitor I, Wee1-Inhibitor-I, Wee1-Inhibitor I |
| Application: | Wee1 inhibitor |
| CAS | 622855-37-2 |
| MW: | 362.77 D |
895.00€
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