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Anti-NKX3.1 (Metastatic Prostate Adenocarcinoma Marker) Monoclonal Antibody (Clone: NKX3.1/2836)
Anti-NKX3.1 (Metastatic Prostate Adenocarcinoma Marker)...

Item number: ABE-36-2859-100

NKX3.1 is a prostate specific gene encoding a transcription factor that plays an important role in normal prostate development and carcinogenesis. It is a prostatic tumor suppressor gene located on chromosome 8p21.2, which frequently undergoes a loss of heterozygosity. NKX3.1 expression is highly restricted in...
Keywords: Anti-NKX3.1, Anti-NKX3-1, Anti-Homeobox protein Nkx-3.1, Anti-Homeobox protein NK-3 homolog A, Anti-NKX3.1 (Metastatic...
Application: ELISA, IHC
Host: Mouse
Species reactivity: human
From 375.00€ *
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Gefitinib-based PROTAC 3
Gefitinib-based PROTAC 3

Item number: Cay28597-10

Gefitinib-based PROTAC 3 is a proteolysis-targeting chimera (PROTAC) comprised of the EGF receptor (EGFR) inhibitor gefitinib (Cay-13166) linked to the von Hippel-Lindau (VHL) E3 ubiquitin ligase ligand VHL ligand 1 (Cay-21591). In cell-based assays, gefitinib-based PROTAC 3 induces degradation of EGFR containing...
Keywords: Gefitinib-based Proteolysis-targeting Chimera 3,...
Application: EGFR-L858R degradation
CAS 2230821-27-7
MW: 934.5 D
From 32.00€ *
Review