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N-(2-phenylethyl)-Indomethacin amide
N-(2-phenylethyl)-Indomethacin amide

Item number: Cay70272-1

N-(2-phenylethyl)-indomethacin amide (N-2PIA) is one of several aromatic amides of indomethacin reported to be potent and selective reversible inhibitors of COX-2. N-2PIA inhibits human recombinant and ovine COX-2 with IC50 values of 0.06 and 0.125 µM, respectively. It is over 400 times less potent as an inhibitor...
Keywords: N-2PIA, N-(2-phenylethyl)-1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetamide
Application: COX-2 inhibitor
CAS 261766-32-9
MW: 461 D
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