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COVID-19 Research
Remdesivir
Remdesivir

Item number: Cay30354-5

Remdesivir is a prodrug form of the antiviral nucleoside analog GS-441524 (Cay-30469). Upon entry into cells, remdesivir is metabolized into the nucleotide triphosphate GS-441524. Remdesivir is active against Middle East respiratory syndrome coronavirus (MERS-CoV) and severe acute respiratory syndrome CoV...
Keywords: GS-5734, N-[(S)-hydroxyphenoxyphosphinyl)-L-alanine, 2-ethylbutyl ester, 6-ester with...
Application: GS-441524 prodrug, SARS type antiviral
CAS 1809249-37-3
MW: 602.6 D
From 110.00€ *
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COVID-19 Research
SARS-CoV-2 Inhibitor Screening Kit
SARS-CoV-2 Inhibitor Screening Kit

Item number: AG-48B-0001-KI01

To screen compounds that inhibit the binding of the viral protein SARS-CoV-2 Spike Protein (RBD) to its human receptor ACE2. Coronaviruses (CoVs) are enveloped non-segmented positive-sense single-stranded RNA viruses and can infect respiratory, gastrointestinal, hepatic and central nervous system of human and many...
Keywords: COVID-19 Inhibitor Screening Kit, 2019-nCoV Inhibitor Screening Kit, 2019-nCoV Spike Protein S1 (RBD)/ACE2 Inhibitor...
Application: Compound Screening
Reactivity: Human
715.00€ *
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COVID-19 Research
PLpro (SARS Coronavirus) (rec.) (His)
PLpro (SARS Coronavirus) (rec.) (His)

Item number: SBB-DE0024-C050

The severe acute respiratory syndrome coronavirus papain-like protease (SARS-CoV PLpro) is involved in the processing of the viral polyprotein. Proteolytic processing of the coronavirus replicase poly-protein is essential for generating a functional virus replication complex. PLpro possesses both deubiquitinating or...
Keywords: Papain-like Proteinase, SARS Coronavirus Main Proteinase, Non-structural Protein 3, PL2-PRO, Nsp3
Application: Assays
Reactivity: Sars-cov
MW: 37 kD
212.00€ *
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COVID-19 Research
SARS-CoV-2 (2019-nCoV) Papain-Like Protease Protein , recombinant
SARS-CoV-2 (2019-nCoV) Papain-Like Protease Protein ,...

Item number: E-PKSR030472.50

GenBank: QHD43415.1. Nsp3 is responsible for the cleavages located at the N-terminus of the replicase polyprotein. In addition, PL-PRO possesses a deubiquitinating/deISGylating activity and processes both 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains from cellular substrates. Participates together with nsp4 in...
Keywords: Non-structural protein 3, nsp3, PL2-PROPapain-like proteinase, PL-PRO, SARS coronavirus main proteinase
Reactivity: Sars-cov-2
MW: 34 kD
From 243.00€ *
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COVID-19 Research
COVID-19 IgM/IgG Rapid Test
COVID-19 IgM/IgG Rapid Test

Item number: E-UNCOV-40

COVID-19 (Corona Virus Disease) is an infectious disease caused by the most recently discovered coronavirus SARS-CoV-2. This highly contagious new virus and disease were unknown before the outbreak began in Wuhan, China which spread all over the world very quickly. COVID-19 IgG/IgM Rapid Test (Whole Blood/...
Keywords: SARS-CoV-2 antibody test
Application: Lateral flow
Reactivity: Human
245.00€ *
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COVID-19 Research
Anti-ACE2 (human), mAb AC18F (ATTO488)
Anti-ACE2 (human), mAb AC18F (ATTO488)

Item number: AG-20A-0032-C100

Recognizes human ACE2. Liquid. 0.2µm-filtered solution in PBS, pH 7.4. Contains no preservatives. ACE2 has direct effects on cardiac functions. It is expressed predominantly in vascular endothelial cells of the heart and kidney. ACE2 converts angiotensin I to angiotensin 1-9. ACE2 was also identified as a functional...
Keywords: SARS Receptor, Angiotensin-converting Enzyme 2, ACEH
Application: ELISA, FC, WB
Reactivity: Human
From 187.00€ *
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COVID-19 Research
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Anti-SARS-CoV Nucleocapsid (N) Protein
Anti-SARS-CoV Nucleocapsid (N) Protein

Item number: 200-401-A50

Protein function: Major structural component of virions that associates with genomic RNA to form a long, flexible, helical nucleocapsid. [The UniProt Consortium]
Keywords: Anti-N, Anti-NC, Anti-9a, Anti-Protein N, Anti-Nucleoprotein, Anti-Nucleocapsid protein
Application: ELISA, WB, IF
577.00€ *
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COVID-19 Research
E-64
E-64

Item number: 51363.10

Purity: >99% (HPLC). Cell-permeable and irreversible inhibitor of calpain and other cystein proteases. Soluble in aqueous solutions. Stock solution: 1 mM, stable for months at -20 °C. Effective concentration: 1-10 µM.
Keywords: E-64, Aloxistatin
Application: Inhibitor of cysteine proteases
CAS 66701-25-5
From 72.00€ *
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COVID-19 Research
Ruxolitinib
Ruxolitinib

Item number: AG-CR1-3624-M025

White to off-white solid. Soluble in DMSO or ethanol. Insoluble in water. Antineoplastic, anti-inflammatory and immunomodulating agent, Orally bioavailable potent ATP mimetic that inhibits both JAK1 and JAK2 with IC50 values of 2.7 and 4.5nM, respectively and is less selective for JAK3 (IC50 = 322nM), Affects DC...
Keywords: INCB018424, INC 424
Application: JAK1 inhibitor, JAK2 inhibitor
CAS 941678-49-5
MW: 306,4 D
From 72.00€ *
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COVID-19 Research
E-64d
E-64d

Item number: Cay13533-1

Cysteine proteases are a class of enzymes containing an active-site cysteine residue that is important in protein degradation pathways. E-64d, a synthetic analog of E-64 and ethyl ester of E-64c, is an irreversible, membrane-permeable inhibitor of lysosomal and cytosolic cysteine proteases. E-64d inhibits calpain...
Keywords: Aloxistatin, E-64c ethyl ester, EP 453, EST, Loxistatin, NSC 694281,...
Application: Protease inhibitor
CAS 88321-09-9
MW: 342.4 D
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COVID-19 Research
Auranofin
Auranofin

Item number: Cay15316-25

Auranofin is a gold-thiol complex with anti-inflammatory and immunosuppressive actions. It potently inhibits thioredoxin reductase (IC50 = 0.2 µM), preventing reduction of thioredoxin and altering oxidative signaling relevant to DNA synthesis, transcription, apoptosis, and disease. Auranofin blocks LPS-mediated...
Keywords: NSC 321521, Ridauragold thiol, SKF 39162, [1-(thio-kappaS)-beta-D-glucopyranose 2,3,4,6-tetraacetato](triethylphosphine)-gold
Application: Thioredoxin reductase inhibitor
CAS 34031-32-8
MW: 678.5 D
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COVID-19 Research
Hydroxychloroquine (sulfate)
Hydroxychloroquine (sulfate)

Item number: Cay17911-50

Hydroxychloroquine (HCQ) is a synthetic quinine derivative commonly used as an antimalarial drug. It is also useful in managing systemic lupus erythematosus, rheumatoid arthritis, and other diseases. HCQ inhibits autophagy and induces autophagic cell death (IC50 = 30 µM), suggesting potential applications in...
Keywords: HCQ, NSC 4375, 2-[[4-[(7-chloro-4-quinolinyl)amino]pentyl]ethylamino]-ethanol, monosulfate
Application: Antimalarial, Lupus erythematosus suppressant
CAS 747-36-4
MW: 434 D
From 32.00€ *
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